Faculty Opinions recommendation of Two cases of multidrug-resistant genitourinary Mycoplasma genitalium infection successfully eradicated with minocycline.

Author(s):  
Catriona Bradshaw
2018 ◽  
Vol 62 (5) ◽  
Author(s):  
Susanne Paukner ◽  
Astrid Gruss ◽  
Jørgen Skov Jensen

ABSTRACT The pleuromutilin antibiotic lefamulin demonstrated in vitro activity against the most relevant bacterial pathogens causing sexually transmitted infections (STI), including Chlamydia trachomatis (MIC 50/90 , 0.02/0.04 mg/liter; n = 15), susceptible and multidrug-resistant Mycoplasma genitalium (MIC range, 0.002 to 0.063 mg/liter; n = 6), and susceptible and resistant Neisseria gonorrhoeae (MIC 50/90 , 0.12/0.5 mg/liter; n = 25). The results suggest that lefamulin could be a promising first-line antibiotic for the treatment of STI, particularly in populations with high rates of resistance to standard-of-care antibiotics.


2017 ◽  
Vol 36 (9) ◽  
pp. 1565-1567 ◽  
Author(s):  
J. F. Braam ◽  
L. van Dommelen ◽  
C. J. M. Henquet ◽  
J. H. B. van de Bovenkamp ◽  
J. G. Kusters

2017 ◽  
Vol 66 (5) ◽  
pp. 796-798 ◽  
Author(s):  
Jodie Dionne-Odom ◽  
William M Geisler ◽  
Kristal J Aaron ◽  
Ken B Waites ◽  
Andrew O Westfall ◽  
...  

2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Romain Palich ◽  
Marie Gardette ◽  
Cécile Bébéar ◽  
Éric Caumes ◽  
Sabine Pereyre ◽  
...  

2019 ◽  
Vol 30 (5) ◽  
pp. 512-514 ◽  
Author(s):  
Allison M Glaser ◽  
William M Geisler ◽  
Amy E Ratliff ◽  
Li Xiao ◽  
Ken B Waites ◽  
...  

Mycoplasma genitalium (MG) infection is a sexually transmitted infection that causes up to 25% of nongonococcal urethritis (NGU). MG strains carrying genetic markers of antimicrobial resistance that may affect treatment outcomes are increasingly recognized as a public health concern. We present two cases of persistent MG NGU with strains carrying both macrolide and quinolone resistance-associated mutations that were eradicated successfully by an extended course of minocycline.


2010 ◽  
Vol 44 (7) ◽  
pp. 16
Author(s):  
MARY ANNE JACKSON
Keyword(s):  

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