Faculty Opinions recommendation of Role of the Nav1.7 R1150W amino acid change in susceptibility to symptomatic knee osteoarthritis and multiple regional pain.

2011 ◽  
Author(s):  
Jason McDougall
Keyword(s):  
Amino Acid ◽  
Knee Osteoarthritis ◽  
Amino Acid Change ◽  
Symptomatic Knee Osteoarthritis ◽  
Symptomatic Knee

scholarly journals Role of the NaV1.7 R1150W amino acid change in susceptibility to symptomatic knee osteoarthritis and multiple regional pain

2010 ◽  
pp. n/a-n/a ◽  
Author(s):  
Ana M Valdes ◽  
Nigel K Arden ◽  
Frances L Vaughn ◽  
Sally A Doherty ◽  
Paul E Leaverton ◽  
...  
Keyword(s):  
Amino Acid ◽  
Knee Osteoarthritis ◽  
Amino Acid Change ◽  
Symptomatic Knee Osteoarthritis ◽  
Symptomatic Knee

Role of ultrasound guided injection of platelet rich plasma (PRP) in knee osteoarthritis patients

QJM ◽  
2021 ◽  
Vol 114 (Supplement_1) ◽  
Author(s):  
Ahmed Emad Mahdy Mohamed ◽  
Mohamed Sobhy Hassan ◽  
Mohamed Gamal Eldin AbdelMotelib
Keyword(s):  
Knee Osteoarthritis ◽  
Platelet Rich Plasma ◽  
Oxford Knee Score ◽  
Reduction Ratio ◽  
Knee Score ◽  
Ultrasound Guided ◽  
Symptomatic Knee Osteoarthritis ◽  
Symptomatic Knee ◽  
The Mean

Abstract Background Multiple promising researches were done regarding using platelet rich plasma (PRP) injection aiming at establishing new minimally invasive treatment option for knee OA and avoiding surgical procedures hazards which could be an option in advanced cases. Thus, our study will be directed towards ultrasound guided injecting of PRP trying to confirm the efficacy of the procedure as a therapeutic option. Objective The study aims to assess of the role of ultrasound guided PRP injection in cases of knee osteoarthritis and follow up of the symptoms outcome. Methods and material Twenty patients with different knee osteoarthritis grades were injected with PRP under ultrasound guidance and the symptoms outcome were followed up by using visual analogue scale (VAS), WOMAC osteoarthritis index, OXFORD knee score, LYSHOLM knee scoring scale at periods of , and weeks post procedure. Results A total of patients were included with the age ranging from - years old, the mean was . years old (SD ± . ). Among them patients ( ) were females and patients ( ) were males. There was statistically significant difference between the different knee pain scoring scales , and weeks after the procedure compared to before injection, where according to VAS score the mean score was . . pre procedure and became . . , . . and . . after , and weeks respectively with mean reduction ratio of . % after months. The extent of the difference over the periods through WOMAC in knee osteoarthritis patients was . . ,. . and . . after , and weeks respectively, compared to . . before the procedure with a mean reduction ratio of . % after months. While according to OXFORD knee score, the patient’s scores were . . before the procedure Vs . . , . . and . . at , and weeks after injection with symptoms mean reduction ratio of . %. According to LYSHOLM knee scoring scale, the mean score was . . pre procedure and became . . , . . and . . after , and weeks respectively with months mean reduction ratio of . %. Conclusion PRP injection in symptomatic knee osteoarthritis patients cause statistically significant improvement of the symptoms.

scholarly journals The role of cumulative physical work load in symptomatic knee osteoarthritis - a case-control study in Germany

2008 ◽  
Vol 3 (1) ◽  
pp. 14 ◽  
Author(s):  
Andreas Seidler ◽  
Ulrich Bolm-Audorff ◽  
Nasreddin Abolmaali ◽  
Gine Elsner ◽  
Knee osteoarthritis Study-group
Keyword(s):  
Knee Osteoarthritis ◽  
Case Control Study ◽  
Work Load ◽  
Case Control ◽  
Physical Work ◽  
Physical Work Load ◽  
Symptomatic Knee Osteoarthritis ◽  
Symptomatic Knee ◽  
Control Study

THE EFFECT OF A TRIPOD CANE ON THE FUNCTIONAL MOBILITY OF PATIENTS WITH KNEE OSTEOARTHRITIS

2020 ◽  
Vol 5 (1) ◽  
pp. 29
Author(s):  
Nelson Sudiyono
Keyword(s):  
Knee Osteoarthritis ◽  
Cross Sectional Study ◽  
Functional Mobility ◽  
Cross Sectional ◽  
Knee Oa ◽  
Walking Aids ◽  
Symptomatic Knee Osteoarthritis ◽  
Symptomatic Knee ◽  
Contralateral Hand ◽  
Painful Knee

Background: Canes have been recommended as walking aids for knee osteoarthritis to reduce the loading on the affected knee. Patients are usually recommended to hold the cane in the contralateral hand to the affected knee. Nevertheless, some patients prefer to hold the cane ipsilateral to the affected knee. However, the effect of using ipsilateral or contralateral tripod cane on functional mobility in patients with knee osteoarthritis is still unknown Objective: To compare the immediate effect of ipsilateral and contralateral tripod cane usage on functional mobility in patients with symptomatic knee osteoarthritis Method: This cross-sectional study involved 30 overweight or obese patients with symptomatic unilateral or bilateral knee osteoarthritis (Kellgren Lawrence grade 2 and 3) who never use a cane. Functional mobility was evaluated with Time Up and Go test in three conditions; without walking aid, with tripod cane contralateral and ipsilateral to the more painful knee. Results: The TUG time of aid-free walking is 4.75 (p < 0.001, 95% CI 3.79 - 5.71) seconds faster than ipsilateral cane use and 6.69 (p < 0.001, 95%CI 5.35 - 8.03) seconds faster than contralateral cane use. The TUG time of ipsilateral cane use is 1,94 (95% CI, 1.13 - 2.79) seconds faster than contralateral. Conclusion: Patients with symptomatic knee OA who use tripod cane ipsilateral to the more painful knee have higher functional mobility than the contralateral.

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