scholarly journals Doenças causadas por enterobacteriaceae morganella morganii e a resistência aos fármacos beta lactâmicos. / Diseases caused by enterobacteriaceae morganella morganii and resistance to beta lactamic drugs.

2021 ◽  
Vol 7 (12) ◽  
pp. 112426-112439
Author(s):  
Yasmin Leilane Oliveira Nascimento ◽  
Helma Gabriele Mugraby Vasconcelos Aguia ◽  
Neuza Biguinati De Barros ◽  
Luan Felipo Botelho Souza
Keyword(s):  
Morganella Morganii

Introdução: Morganella morganii uma bactéria gram-negativa, que se encontra normalmente na flora intestinal normal tanto de humanos quanto em mamíferos. Faz parte da maior família de bactérias gram-negativas de importância clínica as Enterobacteriaceae, ela e conhecida por causar diversas patologias em humanos. Objetivos: A bactéria em discursão tem muita importância clinica pelo fato de causar diversas patologias. Este estudo pretende explorar a resistência aos fármacos beta-lactâmicos, e as diversas doenças que a Morganella morganii causam nos seres humanos. Metodologia: É um estudo básico, que tem como objetivo um estudo exploratório, que tem como finalidade unir informações sobre o tema abordado. Quanto à abordagem trata-se de uma pesquisa qualitativa, no que se refere aos procedimentos técnicos é uma pesquisa bibliográfica que tem como base a pesquisa de materiais já publicados. Conclusão: Com o aumento do número de relatos de doenças a cerca da Morganella morganii e preciso desenvolver um método rápido de detecção e mais estudos a respeito dessa bactéria, pois ela esta se tornando cada vez mais resistente aos antibióticos. Este patógeno deveria ser clinicamente significativo, e os médicos deveriam colocar essa bactéria na lista de possíveis causas das infecções, na hora do atendimento medico ao paciente. Sugerem-se mais estudos a respeito desse microrganismo para ser possivelmente classificada como um patógeno Negligenciado.

Endophtalmie à Morganella morganii après Vitrectomie: Cas Clinique et Revue de la Litérature

2003 ◽  
Vol 220 (3) ◽  
pp. 207-209 ◽  
Author(s):  
Marc Zaninetti ◽  
Edoardo Baglivo ◽  
Avinoam B. Safran
Keyword(s):  
Morganella Morganii ◽  
Cas Clinique

Paraneoplastic pemphigus associated with rapidly progressing endophthalmitis caused by Morganella Morganii: A case report

2021 ◽  
pp. 112067212110334
Author(s):  
Abdullah I Almater ◽  
Mohammed M Abusayf ◽  
Saeed Alshahrani ◽  
Abdullah M Alfawaz ◽  
Hind M Alkatan ◽  
...  
Keyword(s):  
Positive Culture ◽  
Skin Lesions ◽  
Stevens Johnson Syndrome ◽  
Corneal Perforation ◽  
Morganella Morganii ◽  
Paraneoplastic Pemphigus ◽  
First Case ◽  
Johnson Syndrome ◽  
Acute Necrotizing ◽  
The Right

Introduction: The ocular presentation of paraneoplastic pemphigus (PNP) has rarely been reported in the literature. In this report, we describe a 61-year-old male presenting with eruptive skin lesions associated with underlying non-Hodgkin’s lymphoma who had rapid progressive corneal perforation with secondary endophthalmitis in the setting of PNP. Case description: A 61-year-old male presented to the emergency department complaining of skin eruption mimicking Stevens–Johnson syndrome, which was later found to be related to PNP. Initially, the patient complained of progressive ocular surface dryness in both eyes. Meanwhile, he developed mild pain in the right eye associated with blurry vision in both eyes and was managed with lubricants and topical antibiotics. A few days later, he was found to have corneal perforation with features suggestive of left endophthalmitis with possible early panophthalmitis. Intravenous antibiotic was administered, and primary evisceration of the left globe was performed. Histopathology revealed acute necrotizing keratitis and endophthalmitis. Vitreous analysis showed numerous gram-negative bacilli and a positive culture of Morganella morganii. The patient continued to be managed with frequent lubrications and punctual plugs in the fellow eye during the follow-up period. Conclusion: We describe the first case of endophthalmitis developing secondary to PNP-induced corneal melting and perforation. Anticipating unusual infectious sequelae in the setting of PNP might be warranted to actively detect and successfully manage dry eye disease before devastating complications develop.

Cloning and Expression of a Metalloprotease Gene from Morganella morganii Strain ZM

2017 ◽  
Vol 7 (4) ◽  
pp. 613-615
Author(s):  
Leyla Minnullina ◽  
Margarita Sharipova ◽  
Ayslu Mardanova
Keyword(s):  
Cloning And Expression ◽  
Morganella Morganii

scholarly journals Phosphorylation of Nucleosides by the Mutated Acid Phosphatase from Morganella morganii

2000 ◽  
Vol 66 (7) ◽  
pp. 2811-2816 ◽  
Author(s):  
Yasuhiro Mihara ◽  
Takashi Utagawa ◽  
Hideaki Yamada ◽  
Yasuhisa Asano
Keyword(s):  
Acid Phosphatase ◽  
Random Mutagenesis ◽  
Reaction Yield ◽  
Mutant Library ◽  
Morganella Morganii ◽  
Gene Encoding ◽  
E Coli ◽  
Acid Phosphatase Gene ◽  
Phosphate Source

ABSTRACT A novel nucleoside phosphorylation process using the food additive pyrophosphate as the phosphate source was investigated. TheMorganella morganii gene encoding a selective nucleoside pyrophosphate phosphotransferase was cloned. It was identical to theM. morganii PhoC acid phosphatase gene. Sequential in vitro random mutagenesis was performed on the gene by error-prone PCR to construct a mutant library. The mutant library was introduced intoEscherichia coli, and the transformants were screened for the production of 5′-IMP. One mutated acid phosphatase with an increased phosphotransferase reaction yield was obtained. With E. coli overproducing the mutated acid phosphatase, 101 g of 5′-IMP per liter (192 mM) was synthesized from inosine in an 88% molar yield. This improvement was achieved with two mutations, Gly to Asp at position 92 and Ile to Thr at position 171. A decreasedKm value for inosine was responsible for the increased productivity.

scholarly journals Oral Microbiota of the Snake Bothrops lanceolatus in Martinique

2018 ◽  
Vol 15 (10) ◽  
pp. 2122 ◽  
Author(s):  
Dabor Résière ◽  
Claude Olive ◽  
Hatem Kallel ◽  
André Cabié ◽  
Rémi Névière ◽  
...  
Keyword(s):  
Oral Cavity ◽  
Generation Cephalosporin ◽  
Oral Microbiota ◽  
Third Generation ◽  
Beta Lactams ◽  
Morganella Morganii ◽  
Enterococcus Spp ◽  
Bacillus Spp ◽  
Amoxicillin Clavulanate ◽  
Third Generation Cephalosporins

In Martinique, Bothrops lanceolatus snakebite, although relatively uncommon (~30 cases/year), may result in serious complications such as systemic thrombosis and local infections. Infections have been hypothesized to be related to bacteria present in the snake’s oral cavity. In this investigation, we isolated, identified, and studied the susceptibility to beta-lactams of bacteria sampled from the oral cavity of twenty-six B. lanceolatus specimens collected from various areas in Martinique. Microbiota from B. lanceolatus oral cavity was polymicrobial. Isolated bacteria belonged to fifteen different taxa; the most frequent being Aeromonas hydrophyla (present in 50% of the samples), Morganella morganii, Klebsiella pneumoniae, Bacillus spp., and Enterococcus spp. Analysis of antibiotic susceptibility revealed that 66.7% of the isolated bacteria were resistant to amoxicillin/clavulanate. In contrast, the majority of isolated bacteria were susceptible to the third-generation cephalosporins (i.e., 73.3% with cefotaxime and 80.0% with ceftazidime). Microbiota from B. lanceolatus oral cavity is polymicrobial with bacteria mostly susceptible to third-generation cephalosporins but rarely to amoxicillin/clavulanate. In conclusion, our findings clearly support that first-line antibiotic therapy in the B. lanceolatus-bitten patients, when there is evidence of infection, should include a third-generation cephalosporin rather than amoxicillin/clavulanate.

Putrescine, Cadaverine, and Indole Production by Bacteria Isolated from Wild and Aquacultured Penaeid Shrimp Stored at 0,12, 24, and 36°C

2004 ◽  
Vol 67 (1) ◽  
pp. 124-133 ◽  
Author(s):  
R. A. BENNER ◽  
W. F. STARUSZKIEWICZ ◽  
W. S. OTWELL
Keyword(s):  
Litopenaeus Vannamei ◽  
Penaeid Shrimp ◽  
Shewanella Putrefaciens ◽  
Decomposition Temperature ◽  
Morganella Morganii ◽  
Litopenaeus Setiferus ◽  
Plate Counts ◽  
Indole Production ◽  
Vibrio Spp ◽  
Chemical Indicator

Putrescine, cadaverine, and indole production capabilities of bacteria isolated from wild domestic and aquacultured Ni-caraguan penaeid shrimp in progressive decomposition states were evaluated. The numbers and types of microorganisms responsible for the production of putrescine, cadaverine, and indole in wild and aquacultured shrimp increased with increasing decomposition temperature and time. Throughout the storage experiments, mean aerobic plate counts (log/g) ranged from 4.5 to 9.7 and 4.5 to 9.0 for domestic and Nicaraguan shrimp, respectively. Vibrio spp. were more prominent in Nicaraguan shrimp (Litopenaeus vannamei) than in domestic shrimp (Litopenaeus setiferus and Litopenaeus brasiliensis). The only amine-producing (putrescine) microorganism isolated from wild and aquacultured shrimp at all temperatures of decomposition (0, 12, 24, and 36°C) was Shewanella putrefaciens. On the basis of putrescine production by S. putrefaciens at 0 and 12°C and putrescine production by S. putrefaciens, Vibrio spp., and Morganella morganii at 24 and 36°C, putrescine should be considered a potential chemical indicator of decomposition in shrimp.

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