scholarly journals A ascendência da doença de Chagas aguda como uma doença veiculada por alimentos na região Norte do Brasil / The ancestry of acute Chagas disease as a foodborne illness in the northern region of Brazil

2021 ◽  
Vol 7 (12) ◽  
pp. 117507-117524
Author(s):  
Laisy Nazaré Araújo Da Cunha ◽  
Rodrigo Pereira Pamplona Rodrigues ◽  
Francisco das Chagas Alves Do Nascimento ◽  
Andrea das Graças Ferreira Frazão ◽  
Ana Lúcia da Silva Rezende ◽  
...  
2013 ◽  
Vol 142 (1) ◽  
pp. 156-162 ◽  
Author(s):  
Z. DÍAZ-BELLO ◽  
M. C. THOMAS ◽  
M. C. LÓPEZ ◽  
R. ZAVALA-JASPE ◽  
O. NOYA ◽  
...  

SUMMARYTrypanosoma cruzi I, a discrete typing unit (DTU) found in human infections in Venezuela and other countries of the northern region of South America and in Central America, has been recently classified into five intra-DTU genotypes (Ia, Ib, Ic, Id, Ie) based on sequence polymorphisms found in the spliced leader intergenic region. In this paper we report the genotype identification of T. cruzi human isolates from one outbreak of acute orally acquired Chagas disease that occurred in a non-endemic region of Venezuela and from T. cruzi triatomine and rat isolates captured at a guava juice preparation site which was identified as the presumptive source of infection. The genotyping of all these isolates as TcId supports the view of a common source of infection in this oral Chagas disease outbreak through the ingestion of guava juice. Implications for clinical manifestations and dynamics of transmission cycles are discussed.


2009 ◽  
Vol 39 (4) ◽  
pp. 231-232 ◽  
Author(s):  
Henrique de Barros Moreira Beltrão ◽  
Matheus de Paula Cerroni ◽  
Daniel Roberto Coradi de Freitas ◽  
Ana Yecê das Neves Pinto ◽  
Vera da Costa Valente ◽  
...  

2017 ◽  
Vol 235 ◽  
pp. 176-178 ◽  
Author(s):  
Elenild de Góes Costa ◽  
Soraya Oliveira dos Santos ◽  
Mayira Sojo-Milano ◽  
Ednei C.C. Amador ◽  
Erica Tatto ◽  
...  

2009 ◽  
Vol 136 (2) ◽  
pp. 233-235 ◽  
Author(s):  
Rafael de March Ronsoni ◽  
Rubens Vaz Feijó ◽  
Luiz Henrique Melo ◽  
Fabiano Luis Schwingel ◽  
Wilson Jacob Filho ◽  
...  

Nitric Oxide ◽  
2004 ◽  
Vol 11 (2) ◽  
pp. 166-174 ◽  
Author(s):  
Daniela L. Fabrino ◽  
Leonor L. Leon ◽  
Gleydes G. Parreira ◽  
Marcelo Genestra ◽  
Patrícia E. Almeida ◽  
...  

Author(s):  
Ricardo Corral ◽  
Héctor Freilij ◽  
Saúl Grinstein

The presence of circulating immune complexes formed by IgM and IgG (CIC-IgM and CIC-IgG) was investigated, using antigen-specific enzyme-immunoassays (ELISA), in 30 patients with acute Chagas' disease who showed parasitemia and inoculation chagoma. Control population consisted of patients with chronic T. cruzi infection (30), acute toxoplasmosis 10), leishmaniasis (8), rheumatoid arthritis (3) and healthy individuals with negative serology for Chagas* disease (30). Acute chagasic patients were 100% CIC-IgG and 96.66% CIC-IgM positive whereas immunofluorescence tests yielded 90% and 86.66% of positivity for specific IgG and IgM antibodies, respectively. Chronic patients were 68% CIC-IgG and 0% CIC-IgM positive. The 30 negative and the 21 cross-reaction controls proved negative for ELISA (CIC-IgM and CIC-IgG). The high sensitivity of ELISA assays would allow early immunologic diagnosis, as well as prompt treatment, of acute T. cruzi infection, thus eliminating the problem of the false-positive and false-negative results which affects traditional methods for detection of circulating antibodies.


1990 ◽  
Vol 32 (5) ◽  
pp. 379-383 ◽  
Author(s):  
Anna Maria Simonsen Stolf ◽  
Eufrosina Setsu Umezawa ◽  
Bianca Zingales

A radioactive Western-blotting technique was developed by which the reactivity of Immunoglobulins (Igs) from different classes to both membrane radiolabelled and internal parasite antigens is simultaneously identified. The method includes radioiodination of parasites, polypeptide fractionation by SDS-PAGE, Western-blot transfer and autoradiography of the immunoblots developed with anti-Igs conjugates labelled with enzymes. The analysis is then performed by the comparison of common bands on the autoradiograms and the respective substrate stained nitrocellulose blots. This technique was used to analyse T. cruzi trypomastigote surface labelled antigens reactive to IgM, IgA and IgG specific antibodies. A different pattern of reactivity with acute Chagas' disease patients sera was thus obtained.


2020 ◽  
Vol 20 (1) ◽  
Author(s):  
Manuel Calvopina ◽  
Gabriela Segovia ◽  
William Cevallos ◽  
Yosselin Vicuña ◽  
Jaime A. Costales ◽  
...  

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