scholarly journals Clinical Manifestation of Gastroesophageal Reflux among Children with Chronic Constipation

2020 ◽  
Vol 12 (3) ◽  
pp. 178-181
Author(s):  
Seyed Mohsen Dehghani ◽  
Reza Poorghaiomi ◽  
Hazhir Javaherizadeh

BACKGROUND Functional gastrointestinal system diseases (FGIDs) are a group of childhood disorders, our knowledge of which is relatively limited. More importantly, the different subgroups among such a disease group are closely interrelated, and their natural courses and interrelations have yet to be fully clarified. Functional constipation and gastroesophageal reflux disease (GERD) are most frequently seen among this group. However, evidence as to whether any relationship exists between them is limited. In this study, we tried to examine the existence or absence of this relationship. METHODS First, patients with functional constipation were identified based on ROME III criteria, which included 205 patients. All patients were classified into two groups of 185 and 20 patients based on their ability to respond to the questions. Then age, sex, duration of constipation, treatment, and symptoms associated with reflux were examined based on the GERD questionnaire (in case group 185) and I-GERD (in case group 20). Score > 11 in the GERD questionnaire and score > 15 in the I-GERD questionnaire were considered as reflux disease. The variables that were evaluated using Chi-square and Fisher exact tests using SPSS software version 19 included age, sex, the onset of constipation, constipation duration, duration of treatment of constipation, ROME III criteria, and symptoms associated with reflux. RESULTS In the current study 205 subjects were included (girls = 49.8%, boys = 50.2%). The mean age of the children was 5.51 ± 3.15 years. Among the Rome III criteria, the most frequent were retentive posturing, painful defecation, history of large stool defecation, defecation less than 2 times per week, stool accumulation in the rectum, and fecal incontinency more than once a week, respectively. The lowest symptom among people with chronic constipation was fecal incontinency. Also, 46.8% of all patients in the study had a positive familial history. In general, there were 29 patients (14.1%) with reflux out of the 205 patients with functional constipation. In the present study, no significant relationship was found between Rome III criteria and reflux. CONCLUSION The frequency of GERD among cases with constipation was 14.1%. There was no significant relationship between Rome III criteria and reflux.

2010 ◽  
Vol 105 (10) ◽  
pp. 2228-2234 ◽  
Author(s):  
Reuben K Wong ◽  
Olafur S Palsson ◽  
Marsha J Turner ◽  
Rona L Levy ◽  
Andrew D Feld ◽  
...  

2011 ◽  
Vol 43 ◽  
pp. S123-S124
Author(s):  
E. Savarino ◽  
P. Zentilin ◽  
M. Frazzoni ◽  
E. Marabotto ◽  
G. Sammito ◽  
...  

2020 ◽  
Vol 9 (3) ◽  
pp. 169-179
Author(s):  
Bunga Fauza Fitri Ajjah ◽  
Teuku Mamfaluti ◽  
Teuku Romi Imansyah Putra

Latar Belakang : Gastroesophageal Reflux Disease (GERD) merupakan penyakit kronik yang terjadi pada masyarakat dewasa terutama mahasiswa. Faktor yang dapat menyebabkan GERD adalah pola makan termasuk jenis-jenis makanan tertentu yang dikonsumsi, frekuensi makan, dan ketidakteraturan makan. Mahasiswa kedokteran selalu berada di bawah tekanan akademik sehingga muncul ketidaknyamanan pencernaan yang memberi dampak bagi kualitas hidup dan aktivitas sehari-hari. Tujuan : Mengetahui hubungan pola makan dengan terjadinya Gastroesophageal Reflux Disease (GERD) pada mahasiswa Program Studi Pendidikan Dokter Fakultas Kedokteran Universitas Syiah Kuala. Metode : Penelitian ini merupakan penelitian deskriptif analitik observasional dengan desain cross sectional. Teknik pengambilan sampel yang digunakan adalah stratified random sampling sebanyak 216 subjek yang memenuhi kriteria inklusi. Pengumpulan data diperoleh dari hasil pengisian kuesioner oleh subjek menggunakan kuesioner pola makan yang sudah divalidasi dan dimodifikasi oleh peneliti dan menggunakan Gastroesophageal Reflux Disease Questionnaire (GERDQ) dalam bahasa Indonesia yang telah valid. Kuesioner pola makan dinilai dari segi keteraturan makan, frekuensi makan, jenis-jenis makanan, dan porsi makanan yang dikonsumsi. Hasil : Subjek yang memiliki pola makan buruk dan mengalami GERD sebanyak 34,2% sedangkan subjek yang memiliki pola makan baik dan tidak mengalami GERD sebanyak 86,5%. Analisis data dilakukan dengan menggunakan uji Chi Square. Hasil analisis data menunjukkan terdapat hubungan antara pola makan dengan terjadinya Gastroesophageal Reflux Disease (GERD) (p = 0,004).Simpulan : Terdapat hubungan antara pola makan dengan terjadinya Gastroesophageal Reflux Disease (GERD) pada mahasiswa Program Studi Pendidikan Dokter Fakultas Kedokteran Universitas Syiah Kuala.


2017 ◽  
Vol 2017 ◽  
pp. 1-5 ◽  
Author(s):  
Takahiro Maeda ◽  
Masuomi Tomita ◽  
Atsushi Nakazawa ◽  
Gen Sakai ◽  
Shinsuke Funakoshi ◽  
...  

This noninterventional cross-sectional study aims to assess the association between functional constipation (FC) and urinary symptoms in female patients with no treatment for urination and defecation. The Rome III criteria for evaluation of defecation, Overactive Bladder Symptom Score (OABSS) for evaluation of urinary symptoms, and clinical features were investigated in 145 female patients. Latent FC and moderate to severe overactive bladder (OAB) were defined on the basis of positivity for two or more of the Rome III criteria and an OABSS ≥ 6 with OABSS Q3 ≥ 2, respectively. In 60 latent FC patients, the OABSS was higher (5.0 versus 3.2, p=0.001), and concurrent moderate to severe OAB symptoms and OAB with urinary incontinence were more frequent than those in 85 nonlatent FC patients (33.3 versus 10.6%, p=0.001, and 31.7 versus 7.1%, p<0.001). Multivariate analysis demonstrated that moderate to severe OAB symptoms were a significant associated factor of latent FC (odds ratio (OR) = 4.125, p=0.005), while latent FC was the only associated factor of moderate to severe OAB and OAB with urinary incontinence (OR = 4.227, p=0.005 and OR = 4.753, p=0.004). In conclusion, moderate to severe OAB symptoms are correlated with FC. Moreover, FC is related to moderate to severe OAB symptoms and to OAB with urinary incontinence.


2009 ◽  
Vol 136 (5) ◽  
pp. A-376-A-376 ◽  
Author(s):  
Reuben K. Wong ◽  
Olafur S. Palsson ◽  
Marsha J. Turner ◽  
Rona L. Levy ◽  
Andrew D. Feld ◽  
...  

2006 ◽  
Vol 38 (10) ◽  
pp. A105
Author(s):  
G. Boccia ◽  
L. Pensabene ◽  
M.A. Sarno ◽  
P. Masi ◽  
E. Bonanno ◽  
...  

2016 ◽  
Vol 56 (2) ◽  
pp. 95
Author(s):  
Indiana Aulia ◽  
Supriatmo Supriatmo ◽  
Emil Azlin ◽  
Atan Baas Sinuhaji

its most common type is functional constipation. The dietary fiber may be useful in childhood functional constipation management, but unfortunately the role of fiber in functional constipation is still less developed.Objective To determine the role of glucomannan in treatment of childhood functional constipation.Methods A crossover randomized controlled trial (RCT) was done from May until July 2012 in a boarding school in Medan, North Sumatera. The subjects were children with functional constipation aged 7 to 12 years. Subjects were randomised into two group receiving glucomannan fiber as polysaccharide gel (group A) and maltodextrin as placebo (group B) with each dose of 100 mg/kg/day (maximum of 5 g/day) diluted in 50 ml water/500 mg for 4 weeks, then after a wash out period we did the crossover of the two groups. Frequency and consistency of stools were recorded into diary sheet for 4 and 8 weeks of treatment. Functional constipation has been diagnosed based on Rome III criteria. Data was analyzed using independent T-test and Chi-square test.Results A total of 36 subjects were eligible with each group consisting of 18 subjects and mean of weight of 25 kg. We found significant difference in stool frequency, treated on glucomannan with P= 0.002 before and P = 0.0001 after the wash out period. For stool consistency, we found difference while treated on glucomannan 9/18 (P= 0.034) in 4 weeks before and 11/18 (P = 0.008) in 4 weeks after the wash out period.Conclusion Glucomannan has significant effect to improve functional constipation especially in 4 weeks treatment.


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