scholarly journals The effect of interval, continuous and combined aerobic exercise on IGF-1 hormone and body composition in type 2 diabetic patients with NAFLD

2021 ◽  
Vol 43 (5) ◽  
pp. 456-468
Author(s):  
Zahra Bayat ◽  
Abbasali Gaeini ◽  
Reza Nuri

Background. IGF-1 hormone decreases in patients with type 2 diabetes and NAFLD. The effect of exercise on this hormone requires further researches. The purpose of this study was to compare the effects of the interval, continuous, and combined aerobic exercise on IGF-1 hormone and body composition in type 2 diabetic patients with NAFLD. Methods. In this study, forty female type 2 diabetes patients with NAFLD (mean age 50.6 ± 4.5 years, height 1.58 ± 0.07 m, weight 74.4 ± 9.9 kg) were randomized into four groups. The exercise training groups performed exercises by cycle ergometer three days a week for eight weeks. The groups included: interval aerobic exercise group (75-80% maximum heart rate), continuous aerobic exercise group (60-75% maximum heart rate), combined exercise group (interval and continuous), and control group. Variance analysis was used for analysis and comparison between groups. The t-dependent test was used for intra-group compression (α≤0.05). Results. Decreased body weight, BMI, waist circumference, waist circumference, waist-to-height ratio, body fat percentage, body fat mass, and increased IGF-1 were significant in all three exercise groups (P≤0.05). In the control group, increased hip circumference and decreased IGF-1 were significant (P≤0.05). Among the three exercise groups, the interval aerobic exercise group had the most effect on improving type 2 diabetic patients with NAFLD. Comparing between the groups, IGF-1, body mass index, waist circumference, hip circumference, and waist-to-height ratio were significant in the interval, continuous, and combined aerobic exercise groups compared to the control group (P≥0.05). Conclusion. Interval, continuous, and combined aerobic exercise improves body composition and hormone IGF-1, and according to the findings, interval aerobic exercise had the greatest effect on diabetic patients with NAFLD. Therefore, it is recommended that these patients participate in aerobic exercise regularly, especially interval aerobic exercise.

2019 ◽  
Vol 55 (1) ◽  
pp. 49-56 ◽  
Author(s):  
Benjamin Ackon Eghan ◽  
Francis Agyemang-Yeboah ◽  
Eliezer Togbe ◽  
Max Efui Annani-Akollor ◽  
Sampson Donkor ◽  
...  

2020 ◽  
Author(s):  
Fatma Boukhayatia ◽  
Ibtissem Oueslati ◽  
Meriem Cheikh ◽  
Asma Kardi ◽  
Fatma Chaker ◽  
...  

Endocrine ◽  
2021 ◽  
Author(s):  
Francesco Mozzanica ◽  
Anna Ferrulli ◽  
Stela Vujosevic ◽  
Alessandro Montuori ◽  
Arianna Cardella ◽  
...  

Abstract Purpose Scarce information on the prevalence and characteristics of olfactory disfunction (OD) in type 2 diabetic (T2D) patients are available. The aims of this study were (1) to assess the olfactory function in T2D patients and to compare it with a control group of individuals without T2D, and (2) to evaluate the differences in OD within T2D patients according to the presence of diabetic complications. Methods A group of 39 T2D patients and a control group of 39 healthy individuals were enrolled. Each subject underwent an evaluation of the olfactory performance using the Sniffing Olfactory Screening Test (SOST) and completed a questionnaire assessing the subjective perception of olfaction. According to the presence of diabetic complications, the group of T2D patients was divided into two subgroups. Non-parametric tests and regression analysis were used for statistical analysis. Results No differences in the subjective perception of olfaction were demonstrated among T2D patients (with and without complications) and controls. A significant difference for the SOST score was demonstrated among the different groups. In particular, OD was more frequent in T2D patients than in controls. In addition, OD was far more frequent in T2D patients with complications. Regression analysis did not demonstrate any significant association between OD and clinical/demographic characteristics of T2D patients. Conclusion T2D patients were more frequently affected by OD. The subgroup analysis suggested a possible relationship between OD and diabetic complications since patients with T2D diabetic complications demonstrated lower olfactory abilities than controls subjects and T2D patients without diabetic complications.


2015 ◽  
Author(s):  
Florentino Carral ◽  
Carmen Ayala ◽  
Antonia Pinero ◽  
Ana Isabel Jimenez ◽  
Coral Exposito ◽  
...  

2013 ◽  
Vol 11 (1) ◽  
pp. 41-48 ◽  
Author(s):  
Heshmat Parsian ◽  
Mojtaba Eizadi ◽  
Davood Khorshidi ◽  
Fattaneh Khanali ◽  
◽  
...  

2019 ◽  
Vol 0 (0) ◽  
Author(s):  
Duong Thi Thuy Ngan ◽  
Nguyen Gia Binh ◽  
Le Thi Huong Lan ◽  
Cuc Thi Thu Nguyen ◽  
Phung Thanh Huong

Summary Background Albuminuria is the standard biomarker for the diagnosis of diabetic nephropathy (DN). However, some patients with persistent microalbuminuria still progress to chronic kidney disease, raising the question of finding a better biomarker. This study aimed to evaluate the correlation of urinary liver-type fatty acid-binding protein (L-FABP) levels with renal function and to compare the role of urinary albumin-to-creatinine ratio (ACR) with urinary L-FABP in early detection of DN in type 2 diabetic patients. Methods The cross-sectional study was done on 106 type 2 diabetic patients and 30 non-diabetic people. L-FABP was measured with the Latex enhanced immunoturbidimetric technique. Results There was a strong and negative correlation between the urine L-FABP levels and eGFR (r = -0.606, p<0.001). The urinary L-FABP levels were significantly higher (p<0.001) in the normoalbuminuria diabetic group than the non-diabetic control group. The ROC-curve analyses in the diabetic patients and the normoalbuminuria diabetic patients showed that the AUCL-FABP was remarkably higher (p<0.001) than the AUCACR. An optimal cutoff value of 5 mg L-FABP/g Cr (with the sensitivity of 98.1% and specificity of 90%) and of 4.3 mg L-FABP/g Cr (with the sensitivity of 100% and specificity of 86.67%) was set to detect DN in the diabetic patients and the normoalbuminuria diabetic patients, respectively. Conclusions The change in urinary L-FABP levels happened earlier than in urinary albumin during renal function impairment. Urinary L-FABP can be used as a better indicator than ACR for early detection of DN in type 2 diabetes.


2021 ◽  
pp. 59-60
Author(s):  
Maniazhagu Dharuman

The purpose of study was to nd out the effects of isolated and combined effects of aerobic dancing and resistance training on resting pulse rate of type-2 diabetic patients. To achieve the purpose of the study, 60 type 2 diabetic patients with the age of 40-45 years from Karaikudi town, Sivaganga District, Tamilnadu were selected as subject at random. The study was formulated as pre and post test random group design, in which sixty subject were divided into four equal groups. The experimental group-1 (n=15, AD) underwent aerobic dancing, experimental group-2 (n=15, RT) underwent resistance training, experimental group – 3 (n=15, COM-T) underwent combined practice of aerobic dancing and resistance training and group-4 (n=15, CG) served as a control group. In this study, three training programme were adopted as independent variable, i.e., aerobic dancing, resistance training and combined training. The resting pulse rate was chosen as dependent variable. It was tested by number of beats per minute, scores recorded in number. The collected pre and post data was critically analyzed with apt statistical tool of analysis of co-variance. The Scheffe's post hoc test was used to nd out pair-wise comparisons between groups. The results of the present study proved that the three training interventions have signicantly altered the resting pulse rate.


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