THE EFFECT OFPRP-THERAPY ON THE STATE OFTHE MICROCIRCULATORY BED USING FIXED ORTHODONTIC APPLIANCES

The effect of PRP-therapy on the state of the vessels of the microvasculature was determined using invariable orthodontic appliances (FOAs). The experiments were carried out on 32 male rabbits of the Dutch breed aged 9 months, which were evenly distributed into four groups: control and experimental groups (I, II, III), 8 animals each. It has been established that treatment with FOAs leads to deterioration of the microcirculatory bed vessels, the development of ischemia and necrosis of the oral mucosa. The use of antibacterial drugs against the background of FOAs leads to a weakly pronounced effect, which develops quite late (on the 20th day in the studied group of rabbits). The most effective method of treatment is the use of PRP-therapy with a pronounced, strong and long-term effect from the very first days with a minimum of contraindications to the procedure. Keywords: microcirculatory bed, PRP-therapy, permanent orthodontic technique.