The long-term effect of anti TNF-α treatment on temporomandibular joints, oral mucosa, and salivary flow in patients with active rheumatoid arthritis: A pilot study

Author(s):  
Ketil Moen ◽  
Anne Grimstvedt Kvalvik ◽  
Sølve Hellem ◽  
Roland Jonsson ◽  
Johan G. Brun
1994 ◽  
Vol 37 (6) ◽  
pp. 824-829 ◽  
Author(s):  
Piet Geusens ◽  
Carine Wouters ◽  
Jos Nijs ◽  
Yebin Jiang ◽  
Jan Dequeker

Oral Diseases ◽  
2021 ◽  
Author(s):  
Yuejiao Zhang ◽  
Qian Liu ◽  
Xiaojie Xu ◽  
Peng Zhou ◽  
Hongyun Zhang ◽  
...  

2020 ◽  
Vol 59 (03) ◽  
pp. 269-275
Author(s):  
Imre Szerb ◽  
Tamás Gál ◽  
Dániel Kiss ◽  
Viktória Nagy ◽  
László Hangody

Abstract Objective The study objective was to evaluate the long-term effect of radiosynoviorthesis (RSO) on the progression of radiological and nuclear-medical osteoarthritic features of hip and ankle joint in patients with osteoarthritis and rheumatoid arthritis. Patients and Methods The study included 89 hip joints of 81 patients, of which 48 had osteoarthritis (OA) and 33 had rheumatoid arthritis (RA). In terms of ankle joints, 64 patients were included of which 43 suffered from OA and 21 from RA. The mean follow-up time was 9.2 years for OA and 8.9 years for RA patients. Patients with RA were the active control group. Structural alterations of the hip joints were evaluated following Kellgren-Lawrence score and of ankle joint following Takakura score for both disease entities. For the evaluation of synovitis 2-phase bone scintigraphy was performed. Results RSO could prevent radiologic status deterioration among 70.6 % of hip osteoarthritic patients and 73.7 % among the hip RA patients. No structural progression was observed in 79.1 % of the treated ankle joints in patients with OA and in 85.7 % of the ankle joints in patients with RA.The scintigraphic response rate for the hip joints of OA patients was 68.6 %, 76.3 % for hip joints of RA patients, 83.1 %, ankle joints of OA patients, and 90.4 % ankle joints of RA patients.The radiographic and scintigraphic RSO response rates were not significantly higher for both joints in RA than OA patients. Conclusion RSO can be a good alternative in the treatment of synovitis and prevention of deterioration of inflammatory and radiographic features even in patients suffering from osteoarthritis and rheumatoid arthritis. RSO may have also a long-term effect to stop or delay progression of both diseases.


1994 ◽  
Vol 43 (2) ◽  
pp. 733-738
Author(s):  
Hisakata Yamada ◽  
Masakazu Kondo ◽  
Tatsuoki Mashima ◽  
Norio Shinohara ◽  
Koichiro Yokoyama ◽  
...  

2013 ◽  
Vol 2 (3) ◽  
pp. 296 ◽  
Author(s):  
Kunal Sah ◽  
Neeraj Grover ◽  
Sunira Chandra ◽  
RanaRandeep Singh ◽  
Alpana Kanwar

Author(s):  
I. Kovach ◽  
N. Gutarova ◽  
V. Alekseeva

The effect of PRP-therapy on the state of the vessels of the microvasculature was determined using invariable orthodontic appliances (FOAs). The experiments were carried out on 32 male rabbits of the Dutch breed aged 9 months, which were evenly distributed into four groups: control and experimental groups (I, II, III), 8 animals each. It has been established that treatment with FOAs leads to deterioration of the microcirculatory bed vessels, the development of ischemia and necrosis of the oral mucosa. The use of antibacterial drugs against the background of FOAs leads to a weakly pronounced effect, which develops quite late (on the 20th day in the studied group of rabbits). The most effective method of treatment is the use of PRP-therapy with a pronounced, strong and long-term effect from the very first days with a minimum of contraindications to the procedure. Keywords: microcirculatory bed, PRP-therapy, permanent orthodontic technique.


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