scholarly journals COMPLICATIONS IN BLOCKING INTRAMEDULLARY OSTEOSYNTHESIS (review)

2020 ◽  
Vol 7 (2) ◽  
pp. 81-84
Author(s):  
A.B.Ogly Mansyrov ◽  
V. Lytovchenko ◽  
M. Berezka ◽  
Ye. Garyachiy ◽  
Rami A.F. Almasri

COMPLICATIONS IN BLOCKING INTRAMEDULLARY OSTEOSYNTHESIS (review) Mansyrov A.B. Ogly, Lytovchenko V., Berezka M., Garyachiy Ye., Rami A.F. Almasri Treatment of diaphyseal bone fractures is a complicated, controversial and ambiguous task. Blocking intramedullary osteosynthesis, which became the standard of treatment, is also not perfect and accompanied by a number of complications. The reasons for their occurrence are connected both with defects in the organization of treatment of patients, and with tactical mistakes, the definition, generalization and prevention of which became the purpose of our study. It was found that typical tactical mistakes were: use of the method against the indications, non-compliance with the technology of blocking intramedullary osteosynthesis and the use of unsubstantiated and inadequate "proprietary methods", making their own "modifications" during the surgery and changing the course of operative intervention, excessive drilling of the bone marrow canal, significant intraoperative traumatism of bone fragments and surrounding soft tissues, incorrect type of lock or timely unfulfilled dynamization, lack of consistency and restorative and rehabilitative treatment. But the most negative effect on the anatomical recovery of the bone and functional recovery of the extremity was the bone marrow canal drilling, performed without the corresponding indications and technical disadvantages. It is obvious that the violation of the endostosis of the endostal negative effect on the reparative capabilities of bone tissue, inhibits the process of bone grafting and delay recovery. Therefore, there is no doubt that the further study of the effect of bone marrow duct penetration in the course of reparative osteogenesis is relevant and appropriate. Key words: blocking intramedullary osteosynthesis, tactical mistakes, fracture, long bones, drilling.   Резюме. УСКЛАДНЕННЯ ІНТРАМЕДУЛЯРНОГО БЛОКУЮЧОГО ОСТЕОСИНТЕЗУ (огляд) Мансиров А.Б. Огли, Литовченко В.О., Березка М.І., Гарячий Є.В., Рами A.Ф. Аль-масри Лікування діафізарних переломів кісток кінцівок є складним, спірним та неоднозначним завданням. Інтрамедулярний блокуючий остеосинтез, який став стандартом їх лікування, також не позбавлений недоліків і супроводжується низкою ускладнень. Причини їх виникнення пов'язані як з дефектами організації лікування хворих, так і з тактичними помилками, визначення, узагальнення та попередження яких і стали метою нашого дослідження. Виявлено, що типовими тактичними помилками є використання методу проти показань, недотримання технології інтрамедулярного блокуючого остеосинтезу та використання необгрунтованих та неадекватних «авторських» методик, внесення власних «поправок» під час виконання операції та зміна ходу оперативного втручання, надлишкове розсвердлювання кістково-мозкового каналу, значна інтраопераційна травматизація кісткових уламків та оточуючих м'яких тканин, невірний тип блокування або вчасно невиконана динамізація, відсутність послідовності у відновному та реабілітаційному лікуванні. Але найбільш негативний вплив на анатомічне відновлення кістки та функціональне відновлення кінцівки мало розсвердлювання кістково-мозкового каналу, виконане без відповідних на те показань і з технічними недоліками. Очевидно, що порушення цілосності ендосту негативно впливає на репаративні можливості кісткової тканини, гальмує процес кісткового зрощення та відтерміновує одужання. Тому не викликає сумнівів, що подальше вивчення впливу розсвердлювання кістково-мозкового каналу на перебіг репаративного остеогенезу є актуальним та доцільним. Ключові слова: інтрамедулярний блоковий остеосинтез, тактичні помилки, перелом, довга кістка, розсвердлювання.   Резюме. ОСЛОЖНЕНИЯ ИНТРАМЕДУЛЛЯРНОГО БЛОКИРУЮЩЕГО ОСТЕОСИНТЕЗА (огляд) Мансыров А.Б. Оглы, Литовченко В.А., Березка Н.И., Гарячий Е.В., Рами A.Ф. Аль-масри Лечение диафизарных переломов костей конечностей является сложной, спорной и неоднозначной задачей. Интрамедуллярный блокирующий остеосинтез, который стал стандартом их лечения, также имеет недостатки и сопровождается рядом осложнений. Причины их возникновения связаны как с дефектами в организации лечения больных, так и с тактическими ошибками. Поэтому целью исследования было их определение, обобщение и пути предупреждения. Установлено, что типичными тактическими ошибками были: применение метода без показаний, нарушение его технологии и применение необоснованных и неадекватных «авторских» методик, внесение собственных «поправок» во время выполнения операции и изменение хода оперативного вмешательства, избыточное рассверливание костно-мозгового канала, значительная интраоперационная травматизация костных отломков и окружающих мягких тканей, неправильно выбранный тип блокирования или не вовремя выполненная динамизация, отсутствие преемственности в восстановительном и реабилитационном лечении. Однако наиболее негативное влияние на анатомическое восстановление кости и функциональное восстановление конечности имело рассверливание костно-мозгового канала, выполненное без соответствующих показаний и с техническими огрехами. Очевидно, что нарушение целостности эндоста негативно влияет на репаративные возможности костной ткани, тормозит процесс костного сращения и отдаляет выздоровление.Поэтому не вызывает сомнений, что дальнейшее изучение влияния рассверливания костно-мозгового канала на течение репаративного остеогенеза является актуальным и целесообразным. Ключевые слова: интрамедуллярный блокирующий остеосинтез, тактические ошибки, перелом, длинная кость, рассверливание.

Author(s):  
A.B. Mansyrov ◽  
V.O. Lytovchenko ◽  
Ye.V. Gariachyi

Summary. The main condition for preventing complications of intramedullary blocking osteosynthesis of long bones is following the tactical and technical principles of osteosynthesis and conscious rejection of such surgical techniques and manipulations that can lead to disturbances of the course of reparative processes of bone tissue. Objective. On the basis of the study and summary of the identified complications of intramedullary blocking osteosynthesis of diaphyseal fractures of bones of limbs, to determine ways to prevent complications of the reparation. Materials and Methods. The results of treatment of 403 patients who underwent intramedullary blocking osteosynthesis of the femur, tibia and humerus types A1-A3, B1–B3 and C2 by AO/ASIF were studied and analyzed. Results. Analyzing the technological complications that we have divided, depending on the consequences they led to, early (up to 2 weeks after surgery), late (2 weeks after surgery) and reparative, we found that the most common technological mistakes were incorrect preoperative planning and disruption of technology and surgery, which in 21.6% of cases led to instability of bone fragments in the fracture area, and the absence or disruption of recovery and rehabilitation of patients, which occurred in 26.3% of cases. Disorders of osteosynthesis technology, namely, significant intra-operative traumatization of bone fragments and soft tissues, and non-eliminated soft tissue interposition resulted in inappropriate consolidation of bone fragments in 39% and 13%, respectively. The main cause of reparative complications was bone marrow drilling, which was performed for 56% of the patients with delayed consolidation of bone fragments, 56.3% of the patients with false joints, and 48% of the patients with bone fractures. Conclusions. Strict following the tactical and technical principles of intramedullary blocking osteosynthesis and rejection of bone marrow drilling without indications will reduce the incidence of bone dysregeneration. The study of the effect of bone marrow drilling on reparative bone regeneration in intramedullary blocking osteosynthesis is actual and needs further deep analysis.


2016 ◽  
Vol 23 (1) ◽  
pp. 82-84
Author(s):  
A. D Yamkovoi ◽  
N. S Gavruyshenko ◽  
V. I Zorya

Type A fractures by AO classification were simulated on eight human cadaveric specimens (2 shoulder segments, 3 femur and 3 crus segments). Fixion nails with plastic deformation were used for fixation. The magnitude of force resulting in bone fragments displacement was determined using universal machine at CITO test laboratory. On the basis of the obtained results the recommendations on the potential load in early postoperative period were given.


ScienceRise ◽  
2020 ◽  
pp. 40-50
Author(s):  
Asif Baglar ogly Mansyrov ◽  
Viktor Lytovchenko ◽  
Yevgeniy Garyachiy ◽  
Andriy Lytovchenko

The object of the study: clinical effect of intramedullary blocking osteosynthesis of fractures of the bones of the extremities without reaming of the bone marrow canal. The problem to be solved: determination of the influence of surgical technology of intramedullary blocking osteosynthesis of bone fractures without reaming of the bone marrow canal on the qualitative and anatomical and functional results of treatment. Main scientific results. The term of fusion of bone fragments in complete groups (including all localizations) in the group of patients who underwent surgery with reaming of the bone marrow canal was 4.21±0.46 months, while in the group without reaming of the canal it was much shorter – 3.47±0.51 months Faster functional recovery of the limbs was also observed in cases that precluded bone marrow reaming – 96 % of good and 4 % satisfactory scores were obtained (80 % good and 20 % satisfactory in bone marrow reaming). The technology of closed intramedullary blocking osteosynthesis without reaming of the bone marrow can optimize the time of fusion of bone fragments and get 91 % good and 9 % satisfactory results. Its effectiveness is to reduce the number of satisfactory treatment results by 19 %, the absence of unsatisfactory and increase the share of good results by 23 %. The area of practical use of research results: clinics of traumatological profile of different levels, in which surgical treatment of fractures of the bones of the extremities are done. An innovative technological product: technology of closed intramedullary blocking osteosynthesis without reaming of the bone marrow canal. The area of application of an innovative technological product: clinical practice of using the technology of closed intramedullary blocking osteosynthesis without reaming of the bone marrow canal.


2019 ◽  
Vol 23 (3) ◽  
pp. 257-270
Author(s):  
Ya. M. Alsmadi ◽  
N. V. Zagorodniy ◽  
E. I. Solod ◽  
A. F. Lazarev ◽  
M. A. Abdulkhabirov ◽  
...  

Аbctract. Treatment of long bones fractures of the extremities has a particular relevance in modern traumatology due to their high frequency, as well as a large number of deaths in patients with polytrauma. It is dangerous to perform an urgent final osteosynthesis in severe patients because of the possibility of shock and the deterioration of the condition of the injured. Therefore, the principle of Damage control with urgent fixation of damaged segments by external fixation and their subsequent replacement (converse) to intramedullary osteosynthesis had a particular relevance in the treatment of patients with long bones fractures. Purpose: Improving treatment outcomes for patients with long bones fractures. Materials and methods. In the present study, a retrospective analysis of using conversion osteosynthesis in the treatment of 120 patients with long bones extremities fractures in a multidisciplinary hospital was carried out. For a better analysis of the results of treatment, we divided the patients into two groups: The first group 44 patients with fractures of the long bones with polytrauma according to the ISS severity scale> 17. The second group consists of 76 patients with closed isolated unstable comminuted fractures of the long bones with severe post-traumatic edema, who have a high risk of significant trauma of soft tissues. Results. The most optimal time for conversion osteosynthesis to patients with polytrauma was 7-12 days, which prevented the occurrence of traumatic shock; and for patients with closed isolated unstable fractures of long bones with significant of post-traumatic edema for conversion osteosynthesis, the optimal time was 3-7 days after injury, which prevented the occurrence of inflammatory complications in the postoperative period. Conclusion. The study confirmed the feasibility of conversion osteosynthesis in the treatment of patients with diaphyseal fractures. The use of the technique of transferring the fixation of fragments by the external fixation device to the internal osteosynthesis (conversion) contributed to a reduction in the duration of inpatient treatment of patients with fractures of the long bones.


Author(s):  
A. D. Yamkovoi ◽  
N. S. Gavruyshenko ◽  
V. I. Zorya

Type A fractures by AO classification were simulated on eight human cadaveric specimens (2 shoulder segments, 3 femur and 3 crus segments). Fixion nails with plastic deformation were used for fixation. The magnitude of force resulting in bone fragments displacement was determined using universal machine at CITO test laboratory. On the basis of the obtained results the recommendations on the potential load in early postoperative period were given.


2011 ◽  
Vol 18 (4) ◽  
pp. 53-59
Author(s):  
Yusif Abul'fatovich Amiraslanov ◽  
A O Zhukov ◽  
I V Borisov ◽  
A P Ivanov ◽  
Yu A Amiraslanov ◽  
...  

Modern concept for the treatment of long bones fractures complicated by purulent infection is presented. The main principles of this concept are the determination of volume and pattern of bone and soft tissue injury, radical debridement, stable bone fragments' fixation, use of primary and early reconstructive-restorative operations for substitution of bone and soft tissue defects. Treatment results for 268 patients (289 extremity segments) have been analyzed. Applied method of grouping patients with complicated long bone fractures by the pattern and volume of injury enables to determine the volume of debridement, terms and steps of osteosynthesis and reconstructive-plastic operations. Good and satisfactory results have been achieved in 88% of cases.


2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Jing Li ◽  
Heyangzi Li ◽  
Simin Cai ◽  
Shi Bai ◽  
Huabo Cai ◽  
...  

Abstract Background Recent studies demonstrated that autologous mitochondria derived from bone marrow mesenchymal stem cells (BMSCs) might be valuable in the treatment of spinal cord injury (SCI). However, the mechanisms of mitochondrial transfer from BMSCs to injured neurons are not fully understood. Methods We modified BMSCs by CD157, a cell surface molecule as a potential regulator mitochondria transfer, then transplanted to SCI rats and co-cultured with OGD injured VSC4.1 motor neuron. We detected extracellular mitochondrial particles derived from BMSCs by transmission electron microscope and measured the CD157/cyclic ADP-ribose signaling pathway-related protein expression by immunohistochemistry and Western blotting assay. The CD157 ADPR-cyclase activity and Fluo-4 AM was used to detect the Ca2+ signal. All data were expressed as mean ± SEM. Statistical analysis was analyzed by GraphPad Prism 6 software. Unpaired t-test was used for the analysis of two groups. Multiple comparisons were evaluated by one-way ANOVA or two-way ANOVA. Results CD157 on BMSCs was upregulated when co-cultured with injured VSC4.1 motor neurons. Upregulation of CD157 on BMSCs could raise the transfer extracellular mitochondria particles to VSC4.1 motor neurons, gradually regenerate the axon of VSC4.1 motor neuron and reduce the cell apoptosis. Transplantation of CD157-modified BMSCs at the injured sites could significantly improve the functional recovery, axon regeneration, and neuron apoptosis in SCI rats. The level of Ca2+ in CD157-modified BMSCs dramatically increased when objected to high concentration cADPR, ATP content, and MMP of BMSCs also increased. Conclusion The present results suggested that CD157 can regulate the production and transfer of BMSC-derived extracellular mitochondrial particles, enriching the mechanism of the extracellular mitochondrial transfer in BMSCs transplantation and providing a novel strategy to improve the stem cell treatment on SCI.


Bone ◽  
2016 ◽  
Vol 83 ◽  
pp. 280-281
Author(s):  
M.T. Nervegna ◽  
M. Lewicki ◽  
J. Rodriguez ◽  
C. Bozzini ◽  
P.M. Mandalunis

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