Morphological prerequisites for the formation of fascial duplication in the elimination of damage to the anterior rectal wall during prostatectomy

Background Intraoperative rectal injury in prostatectomy patients is an uncommon but severe complication. Particular attention is paid to improving the results of healing damage to the anterior rectal wall during prostatectomy.Objective To study the morphological features of the parietal pelvic fascia and the rectal wall to substantiate the possibility of the formation of fascial duplication in the elimination of damage to the anterior rectal wall during prostatectomy.Material and Methods The authors carried out an intravital morphological analysis of the parietal pelvic fascia covering the levator rectum muscle and the anterior rectal wall in 10 men.Results The parietal pelvic fascia contains more powerful bundles of collagen fibers, which in certain areas are partially woven into the fibers of striated muscle tissue. The adventitia of the rectum is characterized by a looser arrangement of the interacting components of the formed connective and smooth muscle tissue. In the studied formations of the small pelvis, the thickness of collagen fibers separately and in the composition of bundles, as well as the cells of the differon and each fiber separately did not differ, which indicated the identity of their tinctorial properties in the compared zones.Conclusion Morphological analysis showed that when juxtaposing and touching the edges of the healing area of the surgical wound without tension, a stable and continuous scar of the fascial duplication is formed, which ensures reliable fusion of the stitched anatomical structures.

Download Full-text

A collagen matrix derived from bladder can be used to engineer smooth muscle tissue

World Journal of Urology ◽

10.1007/s00345-008-0300-1 ◽

2008 ◽

Vol 26 (4) ◽

pp. 307-314 ◽

Cited By ~ 21

Author(s):

Byung-Soo Kim ◽

Anthony Atala ◽

James J. Yoo

Keyword(s):

Smooth Muscle ◽

Muscle Tissue ◽

Collagen Matrix ◽

Smooth Muscle Tissue

Download Full-text

Comparison of serum vaspin levels and vaspin expression in adipose tissue and smooth muscle tissue in pregnant women with and without gestational diabetes

Clinical Endocrinology ◽

10.1111/cen.13403 ◽

2017 ◽

Vol 87 (4) ◽

pp. 344-349 ◽

Cited By ~ 5

Author(s):

Yuping Tang ◽

Ping Qiao ◽

Xiaoxian Qu ◽

Yirong Bao ◽

Yuhong Li ◽

...

Keyword(s):

Adipose Tissue ◽

Smooth Muscle ◽

Gestational Diabetes ◽

Pregnant Women ◽

Muscle Tissue ◽

Smooth Muscle Tissue

Download Full-text

Ultrastructure of smooth muscle tissue in the female reproductive tract: uterus and oviduct

Ultrastructure of Smooth Muscle ◽

10.1007/978-1-4613-0683-2_10 ◽

1990 ◽

pp. 197-220 ◽

Cited By ~ 6

Author(s):

Shingo Fujii ◽

Ikuo Konishi ◽

Hidetaka Katabuchi ◽

Hitoshi Okamura

Keyword(s):

Smooth Muscle ◽

Muscle Tissue ◽

Reproductive Tract ◽

Female Reproductive Tract ◽

Smooth Muscle Tissue

Download Full-text

Radiobiological Evaluation of Dosimetric Plans for Stereotactic Radiotherapy for Prostate Cancer According to Fractionation Regimen

Journal of radiology and nuclear medicine ◽

10.20862/0042-4676-2019-100-5-263-269 ◽

2019 ◽

Vol 100 (5) ◽

pp. 263-269

Author(s):

E. S. Sukhikh ◽

I. N. Sheyno ◽

L. G. Sukhikh ◽

A. V. Taletskiy ◽

A. V. Vertinskiy ◽

...

Keyword(s):

Radiation Therapy ◽

Total Dose ◽

Rectal Wall ◽

Tumor Control ◽

Anterior Rectal Wall ◽

Tumor Control Probability ◽

Equivalent Uniform Dose ◽

Dose Volume Histograms ◽

Dose Volume ◽

Fractionation Regimen

Objective. To determine the most effective irradiation regimen (total dose and dose per fraction) for hypofractionated treatment for prostate carcinomas according the TCP/NTCP radiobiological criteria.Material and methods. Using the tomographic information of five patients with low-risk prostate adenocarcinoma as an example, the authors devised dosimetric radiation therapy plans using the volumetric modulated arc therapy (VMAT) procedure. They considered the range of total doses of 33.5 to 38 Gy administered in 4 and 5 fractions. Based on the equivalent uniform dose concept proposed by A. Niemierko and on the computed differential dose volume histograms, the investigators modeled local tumor control probability (TCP) values, by taking into account the uncertainties of main radiobiological parameters, and estimated normal tissue complication probabilities (NTCP) for the anterior rectal wall as the organ most at risk of irradiation. An effective dosimetric plan was selected according to the UTCP criterion and the probability of complication-free tumor control, i.e. TCP (1 – NTCP).Results. The results of modeling the UTCP criterion show that with a higher total dose, the TCP value increases and so does the NTCP value, therefore the optimal radiation therapy plans are to irradiate with a total dose of 34 Gy over 4 fractions or with a dose of 36–37 Gy over 5 fractions. The difference between the fractionation regimens is that the UTCP value is achieved with a higher TCP value over 4 fractions and with a lower load on the rectal wall over 5 fractions.Conclusion. The choice of a specific fractionation regimen should be determined from the calculated values of differential dose volume histograms for each patient, as well as from radiobiological criteria, such as TCP, NTCP and UTCP.

Download Full-text

ENGINEERING BLADDER SMOOTH MUSCLE TISSUE: A NOVEL APPROACH USING 3-DIMENSIONAL SILK-BASED BIOMATERIALS AND PRIMARY HUMAN SMOOTH MUSCLE CELLS

The Journal of Urology ◽

10.1016/s0022-5347(08)60220-7 ◽

2008 ◽

Vol 179 (4S) ◽

pp. 75-75

Author(s):

Joshua R Mauney ◽

Rosalyn M Adam ◽

Carlos R Estrada

Keyword(s):

Smooth Muscle ◽

Smooth Muscle Cells ◽

Muscle Tissue ◽

Muscle Cells ◽

Bladder Smooth Muscle ◽

Smooth Muscle Tissue ◽

3 Dimensional ◽

Novel Approach

Download Full-text

Transanal advancement of the anterior rectal wall for vaginal fistulas involving the lower rectum

Diseases of the Colon & Rectum ◽

10.1007/bf02587089 ◽

1980 ◽

Vol 23 (4) ◽

pp. 236-241 ◽

Cited By ~ 30

Author(s):

John R. Hilsabeck

Keyword(s):

Rectal Wall ◽

Anterior Rectal Wall ◽

Lower Rectum

Download Full-text

Primary prostatic extragastrointestinal stromal tumor: a case report and literature review

Journal of International Medical Research ◽

10.1177/0300060518791677 ◽

2018 ◽

Vol 46 (10) ◽

pp. 4343-4349 ◽

Cited By ~ 3

Author(s):

Yong-hao You ◽

Yi Zhang

Keyword(s):

Literature Review ◽

Rectal Wall ◽

Smooth Muscle Actin ◽

Treatment Method ◽

Stromal Tumor ◽

Anterior Rectal Wall ◽

Muscle Actin ◽

Pelvic Tumor ◽

Extragastrointestinal Stromal Tumor ◽

Spindle Cells

Objective This study was performed to discuss the characteristics, diagnosis, and treatment of primary prostatic extragastrointestinal stromal tumor (EGIST). Methods The case history data of a patient with an EGIST were analyzed and discussed with a literature review. Results The patient was diagnosed with a pelvic tumor, possibly malignant. We ascertained the diagnosis by exploratory surgery and pathological biopsy. The tumor was present in the prostate and infiltrated and pressed against the anterior rectal wall. Pathological biopsy showed that the tumor comprised spindle cells, which were also present at the junction of the tumor and prostate tissue. Immunohistochemically, the tumor cells were positive for CD117, DOG-1, CD34, and smooth muscle actin and negative for S100 and desmin; Ki-67LI was about 10%. These results support the diagnosis of primary prostatic EGIST. Conclusion The rarity and nonspecific clinical manifestation of prostatic EGIST facilitate misdiagnosis. Diagnosis mainly depends on imaging examination and characteristic histopathological and immunohistochemical features, and GIST must be excluded. Surgery is the main treatment method, and imatinib is suggested for unresectable and malignant EGISTs.

Download Full-text