scholarly journals FTIR Analysis and Phytoconstituents Screening of Aegle Marmelos L. Leaves in Various Extracts

2021 ◽  
Vol 11 (02) ◽  
pp. 76-84
Author(s):  
Tejal Deokar ◽  
Sushama Pawar
Keyword(s):  
Author(s):  
CHINNAIAH KUPPUSWAMY AMUDHA ◽  
FARAH DEEBA ◽  
PETHANNAN RAJARAJAN

Objective: The surging cancer incidence has necessitated the synthesis, characterization and production of green synthesized silver nanoparticles and its effective use. The present study was carried out to assess the antineoplastic potential of the green synthesized silver nanoparticles against breast cancer cell lines. Methods: The rapid biological synthesis of silver nanoparticles was done using Withania somnifera, Aegle marmelos and Taraxacum officinale. The synthesized nanoparticles were characterized using Scanning Electron Microscope (SEM), Energy Dispersive X-Ray Spectroscopy (EDX) and Fourier Transform Infra-Red (FTIR) analysis. Further, the antineoplastic potential of the green synthesized nanoparticles were assessed by MTT assay at an ascending concentration of 25, 50, 100, 250, 500μg/ml against MCF-7 (Breast) cancer cell lines. Results: The synthesized nanoparticles were characterized using SEM, EDX and FTIR analysis which confirmed the formation of silver nanoparticles and were of irregular shape with a size of 26 nm, 18 nm, 94 nm, and its IC50 value was 251.2563±0.59µg/ml, 215.5172±0.41µg/ml and 205.7613±0.37µg/ml for Aegle marmelos, Taraxacum officinale and Withania somnifera respectively against MCF-7 cells. Conclusion: The investigation unveils the fact that phytofabricated AgNPs could be exploited as an effective antineoplastic agent for further medical and pharmaceutical applications.


Planta Medica ◽  
2011 ◽  
Vol 77 (05) ◽  
Author(s):  
M Mujeeb ◽  
NA Siddique ◽  
A Ahmad ◽  
S Ahmad

Planta Medica ◽  
2016 ◽  
Vol 82 (05) ◽  
Author(s):  
B Avula ◽  
AG Chittiboyina ◽  
YH Wang ◽  
S Sagi ◽  
V Raman ◽  
...  

Author(s):  
Ganesh Chandra Jagetia ◽  
Ponemone Venkatesh ◽  
Parampally Archana ◽  
Bhandarkar R. Krishnanand ◽  
Manjeshwar Shrinath Baliga

2014 ◽  
Vol 13 (9) ◽  
pp. 2145-2152 ◽  
Author(s):  
Liliana Lazar ◽  
Laura Bulgariu ◽  
Bogdan Bandrabur ◽  
Ramona-Elena Tataru-Farmus ◽  
Mioara Drobota ◽  
...  

2017 ◽  
Vol 68 (2) ◽  
pp. 317-322
Author(s):  
Anca Mihaela Mocanu ◽  
Constantin Luca ◽  
Alina Costina Luca

The purpose of this research is to synthetize, characterize and thermal degradation of new heterolytic derivates with potential biological properties. The derivates synthesis was done by obtaining new molecules with pyralozone structure which combine two pharmacophore entities: the amidosulfonyl-R1,R2 phenoxyacetil with the 3,5-dimethyl pyrazole which can have potential biological properties. The synthesis stages of the new products are presented as well as the elemental analysis data and IR, 1H-NMR spectral measurements made for elucidating the chemical structures and thermostability study which makes evident the temperature range proper for their use and storage. The obtained results were indicative of a good correlation of the structure with the thermal stability as estimated by means of the initial degradation temperatures as well as with the degradation mechanism by means of the TG-FTIR analysis.


Author(s):  
Gattu Sampath ◽  
Muthusamy Govarthanan ◽  
Neelamegam Rameshkumar ◽  
Dai-Viet N. Vo ◽  
Muthukalingan Krishnan ◽  
...  

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