Phytochemical analysis of leaves of Aegle marmelos from Himalayan Region

2020 ◽  
Vol 21 (4) ◽  
Keyword(s):  
Himalayan Region ◽  
Phytochemical Analysis ◽  
Aegle Marmelos

scholarly journals IN VITRO - ANTIOXIDANT AND PRELIMINARY PHYTOCHEMICAL ANALYSIS OF AEGLE MARMELOS (L.) CORREA. LEAF EXTRACT

2017 ◽  
Vol 10 (6) ◽  
pp. 367
Author(s):  
Samidha M Pawaskar ◽  
Sasangan Kc
Keyword(s):  
Hydroxyl Radical ◽  
Leaf Extract ◽  
Radical Scavenging ◽  
Reducing Power ◽  
Total Phenolic ◽  
Phytochemical Analysis ◽  
Aegle Marmelos ◽  
Leaf Powder ◽  
Phenolic And Flavonoid

Objective: In this study, the leaf powder of Aegle marmelos (L.) Correa. was subjected to preliminary phytochemical and in vitro antioxidant analysis. Methods: The freshly prepared plant leaf extract was subjected to preliminary phytochemical screening, which revealed the presence of alkaloids, tannins, saponins, flavonoids, glycosides, phenolic compounds, terpenoids, and steroids. Reducing power, superoxide (SO) anion radical, nitric oxide (NO) radical, and hydroxyl radical scavenging assays were carried out to evaluate the antioxidant potential of the methanolic leaf extract of this plant. The amounts of total phenolic and flavonoid compounds were also determined. Results: This study has revealed that the A. marmelos (L.) Correa. leaf extract showed considerably high amounts of most of the phytochemicals, total antioxidant capacity, total phenolic, and flavonoid content. The study also indicated that the A. marmelos (L.) Correa. showed comparatively good scavenging activity, i.e., inhibition of hydroxyl radical, NO and SO anion scavenging and reducing power activities when compared with the respective standards. Conclusion: The leaf powder of A. marmelos (L.) Correa. can be used as easily accessible source of natural antioxidant and as a possible food supplement or in pharmaceutical industry.

scholarly journals ANTI BACTERIAL AND BIOFILM INHIBITORY ACTIVITIES OF AEGLE MARMELOS METHANOL LEAF EXTRACT

2021 ◽  
Vol 9 (09) ◽  
pp. 165-173
Author(s):  
Gujjari Sreehitha Pratap ◽  
Keyword(s):  
Antibacterial Activity ◽  
Biologically Active ◽  
Diffusion Method ◽  
Antibiofilm Activity ◽  
Phytochemical Analysis ◽  
Aegle Marmelos ◽  
Leaf Extracts ◽  
Biofilm Inhibition ◽  
Microbial Strains ◽  
Elisa Plate

The Aegle marmelos commonly known as BAEL belongs to family Rutaceae plays a role in traditional culture and medication from ancient periods. This plant lacks sufficient evidences regarding the values and components it has. Therefore, we framed out our studies to evaluate the phytochemical analysis, antibacterial activity, antibiofilm activity. These studies are evaluated using different solvents like methanol, acetone, chloroform, toluene leaf extracts of Aegle marmelos. We evaluated the potency of different solvents leaf extracts using Agar well diffusion method. Antibacterial activity was also evaluated using ELISA plate assay. The potency of different solvents extracts to inhibit biofilm of selected microbial strains. In accordance to results, the leaf extracts revealed the presence of several biologically active phytochemicals with highest quantities of carbohydrates, phenols, alkaloids, flavonoids, tannins, saponins, steroids, aminoacids etc. The antibacterial activity was found significant against microbial strains of both gram positive and gram negative bacteria. These strains showed susceptibility nature towards the different solvents extracts with zone of inhibitions (mm). On the other hand, the inhibition of biofilm was also significant at all tested concentrations. The biofilm inhibition of microbial strains was found significant at 1 XMIC, 2 XMIC, 3 XMIC. Based on our studies here we conclude that the different solvents leaf extracts possessed inhibitory activity against selected human pathogenic organisms.

scholarly journals Anticonvulsant activity of Nigella sativa, Aegle marmelos and Benincasa hispida in Pentylenetetrazole induced seizure in Swiss albino mice

2016 ◽  
Vol 7 (3) ◽  
pp. 97-102
Author(s):  
Rejeesh Edavan Puthallath ◽  
Lovelyn Joseph ◽  
Kumaraswamy Kademane ◽  
Sudarshanram Narayan Rao
Keyword(s):  
Nigella Sativa ◽  
Ethanolic Extract ◽  
Water Bath ◽  
Control Group ◽  
Absence Seizure ◽  
Phytochemical Analysis ◽  
Aegle Marmelos ◽  
Swiss Albino Mice ◽  
Benincasa Hispida ◽  
Albino Mice

Aims and Objectives: To test anticonvulsant properties of three medicinal plants with pentylenetetrazole induced seizure test in Swiss albino mice.Materials and Methods: Herbs selected for the work (leaves of Aegle marmelos, seed of Nigella sativa, and fruit of Benincasa hispida) were collected locally from Mangalore, India and were authenticated by a Taxonomist. Aqueous extract of Aegle marmelos leaves (AmAE) and  Ethanolic extract of Nigella sativa seeds (NsEE) were prepared by Soxhlet extraction and separated from solvent using a water bath. Benincasa hispidafruit juice (BhE) was filtered and dried on a water bath. Qualitative phytochemical analysis of the test extracts were done with Preliminary chemical reaction tests, and Liquid chromatography–mass spectrometry (LC/MS). Male Swiss albino mice, 3-4 months of age, weighing 25-30g were used in the study. Extracts and vehicle were administered orally 1 hour prior to inducing convulsions. Test employed for screening anticonvulsant properties was Pentylenetetrazole (PTZ) induced seizure test [60mg/kg/i.p]. Animals were treated with extracts at a dose of 900mg/kg orally. The results were compared with control group and test for analysis of variance and significance were done (ANOVA, Dunnett’s test).Results: Aqueousextract of Aeglemarmelos leaves and Ethanolic extract of Nigella sativa seeds possess anticonvulsant property in Pentylenetetrazole (PTZ) induced seizure model, Crude extract of Benincasahispida fruits did not show statistically signifi cant anticonvulsant property.Conclusions: Aeglemarmelos leaf and Nigella sativa seed possess anticonvulsant propertiesin pentylenetetrazole induced seizures, this is in accordance with many other publishedreports on the same herbs with different animal models and indicates effectiveness inhuman absence seizure patients.Asian Journal of Medical Sciences Vol. 7(3) 2016 97-102

scholarly journals Phytochemical Analysis of Selected Medicinal plants of India

2019 ◽  
Vol 2 (1) ◽  
pp. 19-23
Author(s):  
Narendra Anant Kulkarni ◽  
Jayashree Mane
Keyword(s):  
Cardiac Glycosides ◽  
Chemical Constituents ◽  
Antioxidant Properties ◽  
Phytochemical Analysis ◽  
Tribulus Terrestris ◽  
Mimosa Pudica ◽  
Aegle Marmelos ◽  
Calotropis Gigantea ◽  
Achyranthes Aspera ◽  
Cissus Quadrangularis

The present study has revealed the presence of phytochemicals considered as active medicinal chemical constituents. Important medicinal phytochemicals such as terpenoids, flavonoids, phenols, tannins, steroids, glycosides were studied in the collected samples. Plant Aegle marmelos Corr. having all these phytochemicals. Saponin was found only in two plants out of nine plants i.e. Achyranthes aspera Linn. and Semecarpus anacardium Linn. Terpenoids were found in Aegle marmelos Corr., Calotropis gigantea Linn.R.Br., Mimosa pudica Linn. Terpenoids are reported to have anti-inflammatory, antiviral, antimalarial, inhibition of cholesterol synthesis and antibacterial. Cardiac glycosides content was found in Achyranthes aspera Linn., Aegle marmelos Corr., Mimosa pudica Linn., Tribulus terrestris Linn., Calotropis gigantea Linn.R.Br., Ricinus communis Linn.. Cardiac glycosides have been used for over two centuries as a stimulant in case of cardiac failure. The flavonoids were found in Achyranthes aspera Linn., Aegle marmelos Corr., Calotropis gigantea Linn., Mimosa pudica Linn., Cissus quadrangularis Linn. Mart., Tribulus terrestris Linn. The biological functions of flavonoids apart from its antioxidant properties include protection against allergies, inflammation, free radicals, platelet aggregation, microbes, ulcers, hepotoxins, viruses and tumors.

Phytochemical analysis, Antioxidant and Antiarthritic activities of different solvent extract of Aegle marmelos L. unripe fruit

2020 ◽  
Vol 13 (6) ◽  
pp. 2759
Author(s):  
G Sivakumar ◽  
K Gopalasatheeskumar ◽  
K Gowtham ◽  
E Sindhu ◽  
K Akash Raj ◽  
...  
Keyword(s):  
Phytochemical Analysis ◽  
Aegle Marmelos ◽  
Unripe Fruit ◽  
Solvent Extract

scholarly journals Aegle marmelos Leaf Extract Phytochemical Analysis, Cytotoxicity, In Vitro Antioxidant and Antidiabetic Activities

Plants ◽  
2021 ◽  
Vol 10 (12) ◽  
pp. 2573
Author(s):  
Wasim Ahmad ◽  
Mohd Amir ◽  
Adil Ahmad ◽  
Abuzer Ali ◽  
Amena Ali ◽  
...  
Keyword(s):  
Hepg2 Cells ◽  
Antioxidant Activities ◽  
Glucose Consumption ◽  
Phytochemical Analysis ◽  
Alcoholic Extract ◽  
Aegle Marmelos ◽  
Antioxidant Power ◽  
Ic50 Values ◽  
Ferric Reducing Antioxidant Power

For many years, Aegle marmelos (A. marmelos) has been used medicinally and as a dietary supplement. Despite this, there are minimal research data on A. marmelos phytochemical properties and pharmacological effects. This study aimed to explore the phytoconstituents, cytotoxicity, glucose uptake, and antioxidant and antidiabetic potential of an alcoholic extract of A. marmelos leaf. The cytotoxicity of A. marmelos in HepG2 cells was tested in vitro, and the results revealed that it has strong cytocompatibility and cytoprotective properties. The extract’s antioxidant activities were investigated using 2,2-diphenyl-1-picrylhydrazyl (DPPH) and ferric reducing antioxidant power (FRAP) methods. Antioxidant potential was shown to be quite impressive. The enzymes α-amylase and α-glycosidase were found to be substantially inhibited by A. marmelos, with IC50 values of 46.21 and 42.07 mg/mL, respectively. In HepG2 cells, A. marmelos significantly reduced ROS levels that were elevated due to high glucose and enhanced glucose consumption (p < 0.05). These activities might be due to the enrichment of bioactive phytoconstituents analyzed chromatographically using GC/MS and HPLC. The findings of this study show that A. marmelos could be an effective restorative therapy for diabetes and related diseases.

Phytochemical analysis of Anchusa arvensis roots

Planta Medica ◽  
2008 ◽  
Vol 74 (09) ◽  
Author(s):  
SK Tsermentseli ◽  
AN Assimopoulou ◽  
N Gianovits-Argyriadou ◽  
FI Kanaze ◽  
VP Papageorgiou
Keyword(s):  
Phytochemical Analysis
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