EVALUATE THE RELATION BETWEEN THYROID DISORDERS AND ABNORMAL UTERINE BLEEDING IN REPRODUCTIVE AGE GROUP : A CROSS SECTIONAL STUDY AT ANMMCH, GAYA, BIHAR

2021 ◽  
pp. 15-16
Author(s):  
Kumari Ragini ◽  
Kumar Sourav ◽  
Lata Shukla Diwedi ◽  
Debarshi Jana
Keyword(s):  
Subclinical Hypothyroidism ◽  
Thyroid Dysfunction ◽  
Abnormal Uterine Bleeding ◽  
Uterine Bleeding ◽  
Reproductive Age ◽  
Structural Defects ◽  
Thyroid Disorders ◽  
Thyroid Function Tests ◽  
Age Group ◽  
Reproductive Age Group

Introduction: Abnormal uterine bleeding (AUB) is a common disorder occurring in reproductive age group females. It can be understood as bleeding that occurs from the uterus outside the normal parameters and there is no structural defects in the genital tract. One of the most common association with AUB is thyroid dysfunctions. Hence this study aimed to see the incidence of thyroid related disorders in AUB and also to assess the menstrual pattern. Material and Methods: 100 women suffering from AUB who presented to OPD of Obstetrics and Gynecology department of Anugrah Narayan Magadh Medical College and Hospital, Gaya, Bihar were recruited in the study. All females in 19 to 45 years of age group with abnormal uterine bleeding were included excluding those with previously known thyroid disorder, abortion history within 3 months etc. Thyroid function tests were done in all along with ultrasonography of pelvis region. Statistical analysis done. Results: The bleeding abnormality that was found in the most of the women was heavy menstrual bleeding. Women who presented with thyroid dysfunction were 33%. 23% had subclinical hypothyroidism, 6% had hypothyroidism and 4% had hyperthyroidism. Conclusion: Abnormal Uterine Bleeding has strong association with thyroid disorders. Most common type of disorder is subclinical hypothyroidism. Thus all patient of AUB must be evaluated for thyroid dysfunction

scholarly journals A study of prevalence of thyroid dysfunction in abnormal uterine bleeding

2020 ◽  
Vol 9 (7) ◽  
pp. 2905
Author(s):  
Aditi Rai ◽  
Sapna Raina
Keyword(s):  
Subclinical Hypothyroidism ◽  
Thyroid Dysfunction ◽  
Abnormal Uterine Bleeding ◽  
Uterine Bleeding ◽  
Reproductive Age ◽  
Thyroid Disorders ◽  
Thyroid Disorder ◽  
Age Group ◽  
Total N ◽  
Reproductive Age Group

Background: Abnormal uterine bleeding (AUB) is one of the most frequent presentation to gynecology OPD. AUB is a common but complicated clinical presentation and occurs in 15-20% of women between menarche to menopause and significantly affects the women’s health. Thyroid disorders are more common in women than in men and cause abnormal sexual development, menstrual irregularity, infertility and premature menopause. Objective of this study was to estimate the prevalence of thyroid disorders in women in reproductive age group with AUB.Methods: A hospital based prospective cross sectional observational study was carried out in department of obstetrics and gynecology, Mazumdar-Shaw Cancer and Medical Center and Narayana Hrudayalaya Hospital at Narayana Health City, Bangalore with abnormal uterine bleeding during the period of 2 years (December 2015 to November 2017), total 153 patients were included in the study. All women with AUB in reproductive age group were included. Diagnosed cases of ovarian cyst, uterine fibroid, polyp, adenomyosis, endometriosis and malignant (endometrial and cervical) tumors were excluded. Women who are on drugs or hormone therapy (for past 3 months. IUCD users/oral contraceptives pill user. Patients with known case of thyroid disorder, carcinoma thyroid patients with history of coagulation disorder, liver disorder, renal disorder, tuberculosis.Results: A total N=115 (75.2%) of patients who took part in this study had euthyroid status. The estimated prevalence of thyroid dysfunction was 24.9%. Out of which n=22 (14.4%) had subclinical hypothyroidism, n=14 (9.2%) had overt hypothyroidism, n=2 (1.3%) had hyperthyroidism. The most common thyroid dysfunction amongst the study group was noted to be subclinical hypothyroidism (14.4%).Conclusions: There is a high prevalence of thyroid disorders in cases which are clinically diagnosed as AUB. TSH is most sensitive test in detecting thyroid dysfunction. Subclinical cases need to be treated. Hence thyroid function evaluation should be made mandatory in cases of AUB to detect thyroid dysfunction.

scholarly journals Association between thyroid disorders and abnormal uterine bleeding in reproductive ages

2020 ◽  
Vol 9 (9) ◽  
pp. 3580
Author(s):  
Aiyleen S. Shawl ◽  
Massarat Naz
Keyword(s):  
Subclinical Hypothyroidism ◽  
Strong Association ◽  
Abnormal Uterine Bleeding ◽  
Uterine Bleeding ◽  
Reproductive Age ◽  
Structural Defects ◽  
Thyroid Disorders ◽  
Thyroid Function Tests ◽  
Thyroid Disorder ◽  
Age Group

Background: Abnormal uterine bleeding (AUB) means any bleeding that is not normal in amount, duration, frequency, and cyclicity. It is a common disorder occurring in reproductive age group females. It can be understood as bleeding that occurs from the uterus outside the normal parameters and there are no structural defects in the genital tract. One of the most common associations with AUB is thyroid dysfunctions. Hence, this study aimed to see the incidence of thyroid-related disorders in AUB and also to assess the menstrual pattern.Methods: A total 100 women suffering from AUB who presented to OPD of the gynecology department of L D Hospital Srinagar, Jammu and Kashmir were recruited in the study. All females in 19 to 45 years of age group with abnormal uterine bleeding were included excluding those with a previously known thyroid disorder, abortion history within 3 months, etc. Thyroid function tests were done in all along with ultrasonography of the pelvis region. Data were analyzed using SPSS software v.23.0. and Microsoft office 2007.Results: The bleeding abnormality that was found in most of the women was heavy menstrual bleeding. Out of the 100 patients taken into study 11 had thyroid disorders, out of which subclinical hypothyroidism was most prevalent accounting for 8 cases, 2 cases were found to have hypothyroidism and 1 case of hyperthyroidism was detected.Conclusions: Abnormal uterine bleeding has a strong association with thyroid disorders. The most common type of disorder is subclinical hypothyroidism. Thus, all patient of AUB must be evaluated for thyroid dysfunction.

scholarly journals Influence of thyroid gland in women with abnormal uterine bleeding in reproductive age group

2017 ◽  
Vol 6 (6) ◽  
pp. 2222
Author(s):  
Kavitha Marimuthu ◽  
Malarvizhi Loganathan
Keyword(s):  
Thyroid Dysfunction ◽  
Financial Burden ◽  
Abnormal Uterine Bleeding ◽  
Uterine Bleeding ◽  
Reproductive Age ◽  
Premature Menopause ◽  
Thyroid Disorders ◽  
Age Group ◽  
College Hospital ◽  
Reproductive Age Group

Background: Abnormal Uterine Bleeding is a common complaint encountered in Gynaecology OPD. It occurs in 9-14% of women from Menarche to Menopause affecting quality of life imposing financial burden. Thyroid dysfunction causes broad spectrum of reproductive disorders from abnormal sexual development, menstrual irregularities, infertility and premature menopause. Thyroid disorders are 10 times more common in women and increased prevalence of thyroid disorders in women is possibly due to auto immune nature.Methods: This Prospective study population consisted of 250 women attending the Gynaecology Outpatient Clinic, in Government Dharmapuri Medical College Hospital, with complaints of bleeding problems during menstruation in the age group of 18 to 45 years.Results: Of 250 cases of abnormal uterine bleeding in reproductive age group attending the outpatient department about 68 cases have thyroid dysfunction. The common thyroid dysfunction in our study was hypothyroidism which comprises about 15.6% similarly other thyroid dysfunction are hyperthyroidism in 7.2% and subclinical hypothyroidism in 3.2% and subclinical hyperthyroidism 1.2%.Conclusions: It brings into focus the increased incidence of hypothyroidism among women with menorrhagia and amenorrhea. And increased incidence of hyperthyroidism in women with oligomenorrhea. Early detection by selective screening and specific pharmacotherapy for subclinical thyroid disease early in the course of the disease will prove to be a superior alternative to surgical treatments like hysterectomy.

scholarly journals The study of thyroid profile in abnormal uterine bleeding at tertiary care center, Rajasthan, India

2019 ◽  
Vol 8 (6) ◽  
pp. 2429
Author(s):  
Dinesh Gurjar ◽  
Purnima Pachori ◽  
Sandhya Chaudhary ◽  
Dharmendra Singh
Keyword(s):  
Thyroid Dysfunction ◽  
Abnormal Uterine Bleeding ◽  
Uterine Bleeding ◽  
Reproductive Age ◽  
Selective Screening ◽  
Age Group ◽  
Subclinical Disease ◽  
Menstrual Irregularities ◽  
Thyroid Abnormalities ◽  
Reproductive Age Group

Background: Hypothyroidism and Hyperthyroidism leads to menstrual irregularities. Females with thyroid gland abnormality have chances of reproductive abnormalities ranging from abnormal sexual development, menstrual irregularities, infertility and premature menopause. The objectives were to study the association between thyroid dysfunction and AUB in the reproductive age group (18-45 years), To study the thyroid abnormalities in different types of AUB in the reproductive age group, to establish if screening for thyroid abnormalities is justified using T3, T4 and TSH.Methods: This cross-sectional study conducted among 250 women with ‘abnormal uterine bleeding’ (AUB). Inclusion criteria for participants were females in the age group of 18-45 years, females presenting with abnormal uterine bleeding, with thyroid dysfunction, females who do not have signs of demonstrable pelvic pathologyincluding PID.Results: Majority of the patients belonged to the age group of 24 - 32 years i.e.56.8%, 9.2% cases were nullipara, 44.0% cases have menorrhagia, 32.2% have oliogomennorrhea, 19.6% have amenorrhea. Around 3.6% had Thyromegaly, 12.4% have weight gain in hypothyroidism, 28.4% have fatigue in hyperthyroidism, 6.8% cases have higher T4 level, 18.0% cases have higher TSH level.Conclusions: The risk of progression to overt hypothyroidism (about 5% per year) in patients with subclinical disease and the cost-benefit ratio also emphasises the need for selective screening. Early detection of subclinical disease by selective screening facilitates appropriate therapy early in the course of the disease.

A STUDY OF ASSOCIATION OF THYROID DISORDERS IN PATIENTS WITH ABNORMAL UTERINE BLEEDING

2021 ◽  
pp. 1-2
Author(s):  
MD Nurejjaman ◽  
Anuradha Ghosh ◽  
Shermin Siria Begum ◽  
Debarshi Jana
Keyword(s):  
Thyroid Dysfunction ◽  
Hormonal Treatment ◽  
Abnormal Uterine Bleeding ◽  
Uterine Bleeding ◽  
Reproductive Age ◽  
Thyroid Disorders ◽  
Thyroid Disorder ◽  
Age Group ◽  
Unnecessary Intervention ◽  
Menstrual Disturbances

Introduction: The aim of the study was to determine the association between menstrual disturbances and thyroid dysfunction, to analyze the pattern of menstrual dysfunctions among women with thyroid disorder and to estimate the prevalence of subclinical thyroid diseases among women in the reproductive age group with abnormal uterine bleeding, Materials And Methods: This was an observational study conducted in the department of Obstetrics and Gynaecology, Institute of Post Graduate Medical Education & Research, SSKM Hospital, Kolkata from March 2019 to August 2020. Inclusion criteria were patients attending OPD with age group of 18-45 years, women with any of the following menstrual disturbances- menorrhagia, oligomenorrhoea, hypomenorrhea, polymenorrhoea, amenorrhoea with no pelvic pathology and USG showing normal uterus and ovaries. Conclusion: From our study, it may be concluded that there is a strong correlation of thyroid dysfunction with abnormal uterine bleeding. In the patients with abnormal uterine bleeding, if thyroid disorders are timely diagnosed and treated, the menstrual irregularities settle, and unnecessary intervention like hormonal treatment and surgery like hysterectomy can be avoided. Since thyroid dysfunction is an important treatable cause of abnormal uterine bleeding, estimation of thyroid status should be a part of the battery of investigations being done in the patients of abnormal uterine bleeding.

scholarly journals Evaluation of thyroid dysfunction in patients with menstrual disorders of reproductive age group: a prospective cross-sectional study

2021 ◽  
Vol 10 (2) ◽  
pp. 642
Author(s):  
Anupma Kumari ◽  
Renu Rohatgi ◽  
Amrita Singh
Keyword(s):  
Thyroid Function ◽  
Thyroid Dysfunction ◽  
Reproductive Age ◽  
Thyroid Disorders ◽  
Thyroid Function Tests ◽  
Age Group ◽  
Menstrual Disorders ◽  
Women Of Reproductive Age ◽  
Menstrual Disorder ◽  
Reproductive Age Group

Background: Thyroid disorders specifically the hypothyroidism has been associated with menstrual disturbances in women of reproductive age group. The objective of this study was to estimate the prevalence of thyroid dysfunction and its correlation with menstrual disorders in women of reproductive age group.Methods: A hospital based prospective analytical study was carried out in the department of Obstetrics and Gynaecology of Nalanda Medical College and Hospital, Patna from March 2017 to March 2018. 56 women of reproductive age group between 18 to 45 years presenting with menstrual disorders (like menorrhagia, oligo/hypomenorrhea, polymenorrhea, metrorrhagia, and amenorrhea) were recruited in this study. Thyroid function test was done in all patients. Statistical analysis done.Results: Maximum number of patients were seen in the age group of 31-40 years. Most common menstrual complain was menorrhagia (46.42%) followed by hypo/oligomenorrhoea (17.86%). In patients with menstrual disorders, 41.07 % had thyroid disorders in which subclinical hypothyroidism was prevalent in 17.86%, overt hypothyroidism in 12.5%, and overt hyperthyroidism in 5.35% of the women. Menorrhagia was the commonest menstrual disorder (52.94%) seen in hypothyroid patients followed by polymenorrhoea. A high degree positive correlation was observed between thyroid dysfunction and menstrual disorder (Pearson correlation coefficient, r=0.93).Conclusions: Our study concluded that thyroid dysfunction should be considered as an important etiological factor for menstrual irregularity. Thus, thyroid function tests should be performed in all patients with menstrual irregularities to avoid unnecessary interventions like curettage and hysterectomy.

THE STUDY OF THYROID FUNCTION IN ABNORMAL UTERINE BLEEDING

2021 ◽  
pp. 9-10
Author(s):  
Madhuri Rani ◽  
Kumudini Jha ◽  
Debarshi Jana
Keyword(s):  
Thyroid Dysfunction ◽  
Abnormal Uterine Bleeding ◽  
Uterine Bleeding ◽  
Reproductive Age ◽  
Thyroid Disorders ◽  
Thyroid Disorder ◽  
Age Group ◽  
Medical College ◽  
Menstrual Irregularities ◽  
Abnormal Bleeding

Background:. AUB is any abnormal uterine bleeding in the absence of any palpable pelvic pathology and demonstrable extra genital causes. AUB is responsible for 10% of gynaecological complaints.Hypothyroidism and Hyperthyroidism leads to menstrual irregularities. Females with thyroid gland abnormality have chances of reproductive abnormalities ranging from abnormal sexual development, menstrual irregularities, infertility and premature menopause.The objective of this study is to estimate the prevalence of thyroid disorders in women with abnormal uterine bleeding and to assess the menstrul pattern in women with thyroid disorder Methods: The present study was conducted in the Department of Obstetrics and Gynecology, Darbhanga Medical College and Hospital, Laheriasarai, Bihar. Total100 women of reproductive age group between 15-45 years women with abnormal bleeding were studied.Quantitative determination of T3, T4, and TSH by CLIAestimated in autoanlyser. Results: About 100 women participated in the study in which Most of the subjects belong to 26-30 years of age group(30%)followed by20-25 yrs(22%).13% in age group36-40.menorrhagia was the most common presenting symptom(66%)followed by oligomenorrhoea(21%) Thyroid disorders were prevalent in 22%.hypothyroid in 20%and hyperthyroidism in 2%.Majority had menorrhagia 66%followed by oligomenorrhea21%.among thyroid dysfunction 63.3%had menorrhagia and 36.36% had oligomenorrhea. Conclusions: So, biochemical evaluation of thyroid functioning should be made mandatory in all provisionally diagnosed cases of AUB to detect thyroid dysfunction.

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