scholarly journals Association between thyroid disorders and abnormal uterine bleeding in reproductive ages

Author(s):  
Aiyleen S. Shawl ◽  
Massarat Naz

Background: Abnormal uterine bleeding (AUB) means any bleeding that is not normal in amount, duration, frequency, and cyclicity. It is a common disorder occurring in reproductive age group females. It can be understood as bleeding that occurs from the uterus outside the normal parameters and there are no structural defects in the genital tract. One of the most common associations with AUB is thyroid dysfunctions. Hence, this study aimed to see the incidence of thyroid-related disorders in AUB and also to assess the menstrual pattern.Methods: A total 100 women suffering from AUB who presented to OPD of the gynecology department of L D Hospital Srinagar, Jammu and Kashmir were recruited in the study. All females in 19 to 45 years of age group with abnormal uterine bleeding were included excluding those with a previously known thyroid disorder, abortion history within 3 months, etc. Thyroid function tests were done in all along with ultrasonography of the pelvis region. Data were analyzed using SPSS software v.23.0. and Microsoft office 2007.Results: The bleeding abnormality that was found in most of the women was heavy menstrual bleeding. Out of the 100 patients taken into study 11 had thyroid disorders, out of which subclinical hypothyroidism was most prevalent accounting for 8 cases, 2 cases were found to have hypothyroidism and 1 case of hyperthyroidism was detected.Conclusions: Abnormal uterine bleeding has a strong association with thyroid disorders. The most common type of disorder is subclinical hypothyroidism. Thus, all patient of AUB must be evaluated for thyroid dysfunction.

2021 ◽  
pp. 15-16
Author(s):  
Kumari Ragini ◽  
Kumar Sourav ◽  
Lata Shukla Diwedi ◽  
Debarshi Jana

Introduction: Abnormal uterine bleeding (AUB) is a common disorder occurring in reproductive age group females. It can be understood as bleeding that occurs from the uterus outside the normal parameters and there is no structural defects in the genital tract. One of the most common association with AUB is thyroid dysfunctions. Hence this study aimed to see the incidence of thyroid related disorders in AUB and also to assess the menstrual pattern. Material and Methods: 100 women suffering from AUB who presented to OPD of Obstetrics and Gynecology department of Anugrah Narayan Magadh Medical College and Hospital, Gaya, Bihar were recruited in the study. All females in 19 to 45 years of age group with abnormal uterine bleeding were included excluding those with previously known thyroid disorder, abortion history within 3 months etc. Thyroid function tests were done in all along with ultrasonography of pelvis region. Statistical analysis done. Results: The bleeding abnormality that was found in the most of the women was heavy menstrual bleeding. Women who presented with thyroid dysfunction were 33%. 23% had subclinical hypothyroidism, 6% had hypothyroidism and 4% had hyperthyroidism. Conclusion: Abnormal Uterine Bleeding has strong association with thyroid disorders. Most common type of disorder is subclinical hypothyroidism. Thus all patient of AUB must be evaluated for thyroid dysfunction


Author(s):  
Aditi Rai ◽  
Sapna Raina

Background: Abnormal uterine bleeding (AUB) is one of the most frequent presentation to gynecology OPD. AUB is a common but complicated clinical presentation and occurs in 15-20% of women between menarche to menopause and significantly affects the women’s health. Thyroid disorders are more common in women than in men and cause abnormal sexual development, menstrual irregularity, infertility and premature menopause. Objective of this study was to estimate the prevalence of thyroid disorders in women in reproductive age group with AUB.Methods: A hospital based prospective cross sectional observational study was carried out in department of obstetrics and gynecology, Mazumdar-Shaw Cancer and Medical Center and Narayana Hrudayalaya Hospital at Narayana Health City, Bangalore with abnormal uterine bleeding during the period of 2 years (December 2015 to November 2017), total 153 patients were included in the study. All women with AUB in reproductive age group were included. Diagnosed cases of ovarian cyst, uterine fibroid, polyp, adenomyosis, endometriosis and malignant (endometrial and cervical) tumors were excluded. Women who are on drugs or hormone therapy (for past 3 months. IUCD users/oral contraceptives pill user. Patients with known case of thyroid disorder, carcinoma thyroid patients with history of coagulation disorder, liver disorder, renal disorder, tuberculosis.Results: A total N=115 (75.2%) of patients who took part in this study had euthyroid status. The estimated prevalence of thyroid dysfunction was 24.9%. Out of which n=22 (14.4%) had subclinical hypothyroidism, n=14 (9.2%) had overt hypothyroidism, n=2 (1.3%) had hyperthyroidism. The most common thyroid dysfunction amongst the study group was noted to be subclinical hypothyroidism (14.4%).Conclusions: There is a high prevalence of thyroid disorders in cases which are clinically diagnosed as AUB. TSH is most sensitive test in detecting thyroid dysfunction. Subclinical cases need to be treated. Hence thyroid function evaluation should be made mandatory in cases of AUB to detect thyroid dysfunction.


2021 ◽  
pp. 1-2
Author(s):  
MD Nurejjaman ◽  
Anuradha Ghosh ◽  
Shermin Siria Begum ◽  
Debarshi Jana

Introduction: The aim of the study was to determine the association between menstrual disturbances and thyroid dysfunction, to analyze the pattern of menstrual dysfunctions among women with thyroid disorder and to estimate the prevalence of subclinical thyroid diseases among women in the reproductive age group with abnormal uterine bleeding, Materials And Methods: This was an observational study conducted in the department of Obstetrics and Gynaecology, Institute of Post Graduate Medical Education & Research, SSKM Hospital, Kolkata from March 2019 to August 2020. Inclusion criteria were patients attending OPD with age group of 18-45 years, women with any of the following menstrual disturbances- menorrhagia, oligomenorrhoea, hypomenorrhea, polymenorrhoea, amenorrhoea with no pelvic pathology and USG showing normal uterus and ovaries. Conclusion: From our study, it may be concluded that there is a strong correlation of thyroid dysfunction with abnormal uterine bleeding. In the patients with abnormal uterine bleeding, if thyroid disorders are timely diagnosed and treated, the menstrual irregularities settle, and unnecessary intervention like hormonal treatment and surgery like hysterectomy can be avoided. Since thyroid dysfunction is an important treatable cause of abnormal uterine bleeding, estimation of thyroid status should be a part of the battery of investigations being done in the patients of abnormal uterine bleeding.


2021 ◽  
Vol 8 (2) ◽  
pp. 259-263
Author(s):  
Roshnibala Sahu ◽  
Sudhuanshu Kumar Rath

Abnormal uterine bleeding (AUB) is a frequently encountered clinical presentation in gynecological OPD. They are not life threatening but can cause social, psychological and occupational disturbances. As thyroid hormones play a major role in the menstrual and reproductive function of women, studying for thyroid disorder in patients with AUB should be a logical step.This is a prospective observational study conducted in Kalinga Institute of Medical Sciences, BBSR, Odisha. Two hundred and eighty patients of age group 18 to 45 years presenting with AUB were included in this study. All were subjected to routine investigations along with thyroid function tests.Out of 280 patients, 56 patients (20%) had thyroid abnormality. Among which 26 were diagnosed as subclinical hypothyroidism, 24 had hypothyroidism and 6 patients had hyperthyroidism. The frequent menstrual symptom associated with hypothyroidism and subclinical hypothyroidism was menorrhagia. Oligomenorrhea was seen in 50% of hyperthyroid patients.Any type of menstrual disorder should be considered as a possible presenting symptom of thyroid dysfunction and thyroid assessment deemed necessary in such cases, so that we can treat patients at the earliest and prevent morbidities in later life.


2021 ◽  
pp. 9-10
Author(s):  
Madhuri Rani ◽  
Kumudini Jha ◽  
Debarshi Jana

Background:. AUB is any abnormal uterine bleeding in the absence of any palpable pelvic pathology and demonstrable extra genital causes. AUB is responsible for 10% of gynaecological complaints.Hypothyroidism and Hyperthyroidism leads to menstrual irregularities. Females with thyroid gland abnormality have chances of reproductive abnormalities ranging from abnormal sexual development, menstrual irregularities, infertility and premature menopause.The objective of this study is to estimate the prevalence of thyroid disorders in women with abnormal uterine bleeding and to assess the menstrul pattern in women with thyroid disorder Methods: The present study was conducted in the Department of Obstetrics and Gynecology, Darbhanga Medical College and Hospital, Laheriasarai, Bihar. Total100 women of reproductive age group between 15-45 years women with abnormal bleeding were studied.Quantitative determination of T3, T4, and TSH by CLIAestimated in autoanlyser. Results: About 100 women participated in the study in which Most of the subjects belong to 26-30 years of age group(30%)followed by20-25 yrs(22%).13% in age group36-40.menorrhagia was the most common presenting symptom(66%)followed by oligomenorrhoea(21%) Thyroid disorders were prevalent in 22%.hypothyroid in 20%and hyperthyroidism in 2%.Majority had menorrhagia 66%followed by oligomenorrhea21%.among thyroid dysfunction 63.3%had menorrhagia and 36.36% had oligomenorrhea. Conclusions: So, biochemical evaluation of thyroid functioning should be made mandatory in all provisionally diagnosed cases of AUB to detect thyroid dysfunction.


Author(s):  
Bharat Kumar Bilwal ◽  
Apurva Garg

Background: Abnormal uterine bleeding (AUB) is a common clinical presentation in gynecology. Alteration in thyroid hormones level has been associated with menstrual disturbances. This study is aimed to know the prevalence of thyroid disorders amongst AUB patients and also the different patterns of menstrual abnormalities associated with thyroid disorders.Methods: 100 Patient of clinically diagnosed AUB were taken from gynecology OPD at RNT Medical College Udaipur from October 2019 to March 2019. All the patients from 19 to 45 age groups presenting with menstrual disturbances were tested for thyroid function by measuring ST3, ST4, and S.TSH. Statistical analysis done by percentage formula.Results: Out of 100 women of AUB, majority were in the age group of 31-40 years (38%). 44% presented with menorrhagia. 65% were euthyroid, 17% had subclinical hypothyroidism, 15% had overt hypothyroidism and 3% were diagnosed as hyperthyroid. Subclinical hypothyroidism, overt hypothyroidism and hyperthyroidism were detected mostly in the age group of 31-40 years. The commonest bleeding abnormalities in hypothyroid patient were oligomenorrhoea while most of the hyperthyroid cases were having menorrhagia.Conclusions: The study concludes that biochemical evaluation of thyroid function is an easy, reliable method and should be made mandatory in all cases of AUB.


Author(s):  
Koduru Mounika

Aim: The purpose of the study was to detect thyroid dysfunction in women who had abnormal uterine bleeding Study Design: Menorrhagia was the most common type of bleeding (36%). Thyroid dysfunction was discovered in 32% of the patients (Subclinical hypothyroidism in 17%, Hyper thyroid is 11% and hyperthyroidism in 4 % of cases). The researchers looked at 100 cases of Dysfunctional Uterine Bleeding that were clinically identified at Sree Balaji Medical College and Hospital between March 2014 and August 2016. The patients in this study ranged in age from under 20 to 45 years old. The number of instances with DUB who were between the ages of 31 and 40 is 38 %. Methodology: The parity of the patients ranged from unmarried to 0-5, with the parity 2 group accounting for 37% of all DUB patients and the following assessments were made. Results: Thyroid dysfunction was most common in cases of polymenorrhagia (42.8%), menorrhagia (33.3%), polymenorrhea (28.5%), and oligomenorrhea. (26%). Thyroid dysfunction was most common in the age group 31-40 years, accounting for 77.5% of the population. In 17 % of cases, the primary thyroid malfunction was subclinical hypothyroidism. 3% of hyperthyroid patients were also oligomenorrhocic. The most prevalent thyroid disorder in metrorrhagic patients was subclinical hypothyroidism.


Author(s):  
Kavitha Marimuthu ◽  
Malarvizhi Loganathan

Background: Abnormal Uterine Bleeding is a common complaint encountered in Gynaecology OPD. It occurs in 9-14% of women from Menarche to Menopause affecting quality of life imposing financial burden. Thyroid dysfunction causes broad spectrum of reproductive disorders from abnormal sexual development, menstrual irregularities, infertility and premature menopause. Thyroid disorders are 10 times more common in women and increased prevalence of thyroid disorders in women is possibly due to auto immune nature.Methods: This Prospective study population consisted of 250 women attending the Gynaecology Outpatient Clinic, in Government Dharmapuri Medical College Hospital, with complaints of bleeding problems during menstruation in the age group of 18 to 45 years.Results: Of 250 cases of abnormal uterine bleeding in reproductive age group attending the outpatient department about 68 cases have thyroid dysfunction. The common thyroid dysfunction in our study was hypothyroidism which comprises about 15.6% similarly other thyroid dysfunction are hyperthyroidism in 7.2% and subclinical hypothyroidism in 3.2% and subclinical hyperthyroidism 1.2%.Conclusions: It brings into focus the increased incidence of hypothyroidism among women with menorrhagia and amenorrhea. And increased incidence of hyperthyroidism in women with oligomenorrhea. Early detection by selective screening and specific pharmacotherapy for subclinical thyroid disease early in the course of the disease will prove to be a superior alternative to surgical treatments like hysterectomy.


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