scholarly journals ASSESSMENT OF MORBIDITY AND MORTALITY IN PATIENTS OF ACUTE KIDNEY INJURY USING MODIFIED RIFLE CRITERIA

2021 ◽  
pp. 1-3
Author(s):  
Swadesh Kumar Verma ◽  
Ruchy Thakur ◽  
Shikha Malik
Keyword(s):  
Mechanical Ventilation ◽  
Acute Kidney Injury ◽  
Length Of Stay ◽  
Observational Study ◽  
Prospective Observational Study ◽  
Kidney Injury ◽  
Inotropic Support ◽  
Morbidity And Mortality ◽  
Ventilator Support ◽  
Rifle Criteria

Background: Acute Kidney Injury is well recognized for its impact on the outcome of patients admitted in ICU. It has been associated with increased mortality, increased hospital stay and increased use of healthcare resources.Objective of study is to identify Acute Kidney Injury as per modified RIFLE criteria and calculate the length of stay, morbidity and mortality. Methods: Hospital based Prospective observational study. Total 972 patients >1 month of age admitted in PICU were enrolled. Results: The prevalence of AKI in our study was 46.15% and the prevalence of risk, injury and failure in our study was 26.63%, 11.83% and 7.69% respectively.Increasing severity of AKI was associated with an increasing length of PICU and Hospital stay.Significant factors predicting mortality in AKI as compared to non-AKI were failure, sepsis,mechanical ventilation and inotropic support. Conclusions: pRIFLE is not a sensitive predictor of mortality in initial stages of AKI but if AKI is associated with, inotropic and ventilator support it can predict high mortality.

scholarly journals Relation between fluid balance and incidence of morbidity and mortality rates in critically ill patients prospective observational study

QJM ◽  
2020 ◽  
Vol 113 (Supplement_1) ◽  
Author(s):  
M G A Gerges ◽  
H M M Elazzazi ◽  
M H S A Elsersi ◽  
S A R Mustafa ◽  
M A Saeed
Keyword(s):  
Mechanical Ventilation ◽  
Observational Study ◽  
Critically Ill ◽  
Fluid Balance ◽  
Critically Ill Patients ◽  
Prospective Observational Study ◽  
Mortality Rates ◽  
Morbidity And Mortality ◽  
University Hospitals ◽  
Cumulative Fluid Balance

Abstract Background While administration of fluid can be lifesaving, it has been suggested that the fluid accumulation after initial resuscitation and hemodynamic stabilization can contribute to potentially avoidable adverse effects and less favorable outcomes. Objective The aim of this study is to assess whether positive fluid balance in comparison with negative or even fluid balance is associated with increased morbidity and mortality rates in critically ill patients. Patients and Methods This prospective observational study was performed on 145 Patients older than 18 years admitted to intensive care units at Helwan university hospitals and Ain shams university hospitals during the period from November 2017 till May 2018. Results A total of 145 patients with an ICU mortality rate of 14.5% were enrolled. The median cumulative fluid balance of the 124 patients who survive was -110 ml (IQR -2.1-2.2 L) after the fourth day following randomization while the median cumulative fluid balance of the 21 patients who not survive was 3800 ml (IQR 1.7-5.2 L) after the fourth day in ICU. In our study critically ill patients with fluid balance more than 1.2 litres per day had higher ICU complications: increased risk of AKI, longer ICU and hospital stays, and mechanical ventilation, and fluid balance was independently associated with mortality. Conclusion In the view of this study, we concluded that:Zero fluid balance and negative fluid balance independently associated with decrease mortality and morbidity rates in critically ill patients after 4 days from admission in ICU.There was higher cumulative fluid balance in non survivors compared to survivors. Cumulative fluid balance after 4 days from admission was independently predictive of mortality in a heterogeneous group of critically ill patients.96 hour negative fluid balance in critically ill patients was associated with less length of stay at ICU and less mechanical ventilation duration.Positive fluid balance, mechanical ventilation, vasopressors, and high admission SAPS II, SOFA, APACHE II and KIDGO were significantly associated with high mortality.

scholarly journals Evaluation of Aetiology and Outcome of Acute Kidney Injury in a Tertiary Care Hospital of India- A Prospective Observational Study

2020 ◽  
Author(s):  
VS Gaurav Narayan ◽  
SG Ramya ◽  
Sonal Rajesh Kumar ◽  
SK Nellaiappa Ganesan
Keyword(s):  
Acute Kidney Injury ◽  
Intensive Care ◽  
Observational Study ◽  
Prospective Observational Study ◽  
Tertiary Care ◽  
Kidney Injury ◽  
Rapid Decline ◽  
Care Hospital ◽  
Medical Intensive Care

Introduction: The Acute Kidney Injury (AKI) is a rapid decline in renal filtration function. The aetiological spectrum, prevalence of AKI and outcome is highly variable. This variation exists due to the difference in the criteria used, study population and demographic features. Huge differences are noted when AKI is compared in developing and developed countries. Hence, it is important to analyse the spectrum of AKI to facilitate earlier diagnosis and treatment which shall help in improving the outcome. Aim: To study the prevalence, aetiology and outcome of AKI in the medical intensive care. Materials and Methods: This was a prospective observational study conducted in a medical intensive care for 18 months where 1490 patients were screened and 403 patients were included as AKI by KDIGO criteria. History, examination, appropriate investigations and treatment details including dialysis were noted. The serum creatinine levels were obtained every day, to know the time of onset of AKI, at the time of death or discharge, and after one month for patients who turned up for follow-up. Patients were categorised based on outcome as survivors and nonsurvivors. Survivors were divided into as fully recovered and partially recovered and those who left the Intensive Care Unit (ICU) against medical advice were termed as lost to follow-up. Results: A total of 403 patients (27.04% of 1490) of medical intensive care admissions were found to have AKI. Sepsis was the most common cause of AKI. At the end of the month, 78.4% of AKI patients fully recovered, 1.2% partially recovered and the mortality was 14.9%. Mortality was higher in AKI associated with chronic medical conditions like cardiac failure, chronic liver disease and stroke. Conclusion: If treated early, AKI is mostly reversible. Regional differences in AKI should be studied extensively and local guidelines should be formulated by experts for prevention and early treatment, to improve the disease outcome.

Acute Kidney Injury in Elderly Population: A Prospective Observational Study

Nephron ◽  
2017 ◽  
Vol 138 (2) ◽  
pp. 104-112 ◽  
Author(s):  
Cássia Gomes da Silveira Santos ◽  
Rafael Fernandes Romani ◽  
Ricardo Benvenutti ◽  
João Otávio Ribas Zahdi ◽  
Miguel Carlos Riella ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Observational Study ◽  
Elderly Population ◽  
Prospective Observational Study ◽  
Kidney Injury
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