scholarly journals Evaluation of Aetiology and Outcome of Acute Kidney Injury in a Tertiary Care Hospital of India- A Prospective Observational Study

2020 ◽  
Author(s):  
VS Gaurav Narayan ◽  
SG Ramya ◽  
Sonal Rajesh Kumar ◽  
SK Nellaiappa Ganesan
Keyword(s):  
Acute Kidney Injury ◽  
Intensive Care ◽  
Observational Study ◽  
Prospective Observational Study ◽  
Tertiary Care ◽  
Kidney Injury ◽  
Rapid Decline ◽  
Care Hospital ◽  
Medical Intensive Care

Introduction: The Acute Kidney Injury (AKI) is a rapid decline in renal filtration function. The aetiological spectrum, prevalence of AKI and outcome is highly variable. This variation exists due to the difference in the criteria used, study population and demographic features. Huge differences are noted when AKI is compared in developing and developed countries. Hence, it is important to analyse the spectrum of AKI to facilitate earlier diagnosis and treatment which shall help in improving the outcome. Aim: To study the prevalence, aetiology and outcome of AKI in the medical intensive care. Materials and Methods: This was a prospective observational study conducted in a medical intensive care for 18 months where 1490 patients were screened and 403 patients were included as AKI by KDIGO criteria. History, examination, appropriate investigations and treatment details including dialysis were noted. The serum creatinine levels were obtained every day, to know the time of onset of AKI, at the time of death or discharge, and after one month for patients who turned up for follow-up. Patients were categorised based on outcome as survivors and nonsurvivors. Survivors were divided into as fully recovered and partially recovered and those who left the Intensive Care Unit (ICU) against medical advice were termed as lost to follow-up. Results: A total of 403 patients (27.04% of 1490) of medical intensive care admissions were found to have AKI. Sepsis was the most common cause of AKI. At the end of the month, 78.4% of AKI patients fully recovered, 1.2% partially recovered and the mortality was 14.9%. Mortality was higher in AKI associated with chronic medical conditions like cardiac failure, chronic liver disease and stroke. Conclusion: If treated early, AKI is mostly reversible. Regional differences in AKI should be studied extensively and local guidelines should be formulated by experts for prevention and early treatment, to improve the disease outcome.

Acute kidney injury and it's outcome following maternal near miss event: A prospective observational study from a tertiary care hospital

2021 ◽  
pp. 1753495X2110690
Author(s):  
Geetika Thakur ◽  
Aruna Singh ◽  
Vanita Jain ◽  
Pooja Sikka ◽  
Aashima Arora ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Observational Study ◽  
Prospective Observational Study ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Kidney Injury ◽  
Near Miss ◽  
Care Hospital ◽  
One Year

Purpose Haemorrhage, preeclampsia and sepsis are the leading causes renal dysfunction in women with a maternal nearmiss(MNM) complication. The study aimed to assess the prevalence, pattern and follow up of these women. Methods This was a hospital based prospective observational study, conducted over one year. All women with a MNM leading to acute kidney injury (AKI) were analysed for fetomaternal outcomes and renal function at 1 year of followup. Results Incidence of MNM was 43.04 per 1000 livebirths. 18.2% women developed AKI. 51.1% women developed AKI in the puerperal period. Most common cause of AKI was haemorrhage seen in 38.3% women. Majority of women had s.creatinine between 2.1 to 5 mg/dl and 44.68% required dialysis. 80.8% women recovered fully when the treatment was initiated within 24 h. One patient underwent renal transplant. Conclusion Early diagnosis and treatment of AKI results in full recovery.

scholarly journals Clinical Profile of Acute Kidney Injury in Intensive care unit: a prospective observational study from a rural tertiary care centre in North India

2020 ◽  
Vol 19 (4) ◽  
pp. 685-691
Author(s):  
Shashwat Jindal ◽  
Sandeep Joshi ◽  
Ruby Sharma ◽  
Chander Mohan Adya ◽  
Nitin Gupta
Keyword(s):  
Intensive Care Unit ◽  
Acute Kidney Injury ◽  
Intensive Care ◽  
Observational Study ◽  
Prospective Observational Study ◽  
Tertiary Care ◽  
Kidney Injury ◽  
North India ◽  
Care Centre ◽  
Tertiary Care Centre

Introduction: Acute Kidney Injury is characterized by an acute and potentially reversible deterioration of renal function, which results in failure of the kidney to excrete nitrogenous waste products and to maintain fluid and electrolyte balance. There is marked variation in epidemiological data of Acute Kidney Injury depending upon the definitions used, population being studied and the clinical settings. Aims and Objectives: This study was designed to determine the clinical profile of adult patients with Acute Kidney Injury (AKI) admitted in the medical ICU at a rural tertiary care centre in North India. Materials and Methods: This prospective observational study was conducted on 70 patients of Acute Kidney Injury admitted in the Medical Intensive Care Unit in Department of Medicine at M. M. Institute of Medical Sciences and Research, Mullana, Ambala. AKI was diagnosed and staged for severity according to the KDIGO criteria. Results and Observations: Amongst the 70 cases of AKI, 32 cases (45.7%) were females while 38 cases (54.3%) were males. The mean age at presentation was 55.22 ± 14.91 years. Sepsis was found to be the major cause of AKI. Out of 70 patients in our study, 45 (64.2%) cases were attributed to sepsis. Mortality rate seen in this study was 40% (n=28). Conclusion: Acute Kidney Injury is a common clinical problem encountered in critically ill patients, especially in the medical ICU. Early detection and adequate management is important to reduce AKI related as well as all- cause mortality in critically ill patients. Bangladesh Journal of Medical Science Vol.19(4) 2020 p.685-691

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