A CASE OF PHYLLODES TUMOUR DONE UNDER CONTINOUS THORACIC EPIDURALANAESTHESIA IN A SIX MONTHS PREGNANT FEMALE

2021 ◽  
pp. 83-84
Author(s):  
Manisha Kumari ◽  
Neha Panwar
Keyword(s):  
Perioperative Complications ◽  
Phyllodes Tumor ◽  
Anesthetic Technique ◽  
Thoracic Epidural ◽  
Emergency Procedures ◽  
Female Breast ◽  
Phyllodes Tumour ◽  
Epidural Catheterization ◽  
Breast Tissues ◽  
In Pregnancy

Phyllodes tumor is a rare neoplasm of female breast have its origin from the broepithelial cells of breast. It predominantly occur in females (0.3- 0.5%). Phyllodes in pregnancy are larger in size and rapidly growing may be because of the inuence of pregnancy hormones on the female breast tissues. A 22 year old female with six months of pregnancy with phyllodes tumor of right breast was posted for wide local excision and reconstruction of defect using latissimus dorsi myocutaneous ap. She had presented with swelling of approximately 24cm X10cm X 6cm in her right breast which developed pain since last eight days. She was maintained on the intravenous injection duvadilan (isoxsuprine) 80 mg 8 hourly for three days perioperatively for tocolysis. The case was done using thoracic epidural catheterization at T6-T7 interspace using 0.75% ropivacaine with no perioperative complications. The choice of anesthetic technique for the emergency procedures in pregnancy will depend on the trimester and the type and duration of surgical procedure. Whenever possible, a regional anesthetic technique should be used.

scholarly journals Incidence of Acute and Chronic Post-Thoracotomy Pain in Pediatric Patients

Children ◽  
2021 ◽  
Vol 8 (8) ◽  
pp. 642
Author(s):  
Giuliano Marchetti ◽  
Alessandro Vittori ◽  
Fabio Ferrari ◽  
Elisa Francia ◽  
Ilaria Mascilini ◽  
...  
Keyword(s):  
General Anesthesia ◽  
Pediatric Patients ◽  
Pain Syndrome ◽  
Intercostal Nerve ◽  
Anesthetic Technique ◽  
Intercostal Nerve Block ◽  
Thoracic Epidural ◽  
Burning Pain ◽  
Significant Difference ◽  
Group B

We studied acute and chronic pain in pediatric patients who underwent thoracotomy for benign disease with a follow-up of at least three months. A telephone interview investigated about the presence of pain and the analgesic therapy in progress. The results were compared with the anesthetic technique, postoperative pain and the adequacy of pain therapy, both during the first week after surgery and at the time of interview. Fifty-six families consented to the study. The mean age of the children at surgery was 2.9 ± 4.5 years, while at the time of the interview was 6.5 ± 4.4 years. We performed different anesthetic strategies: Group A: general anesthesia (36 pts); Group B: general anesthesia and thoracic epidural (10 pts); Group C: general anesthesia and intercostal nerve block (10 pts). During the immediate postoperative period, 21 patients (37.5%) had at least one painful episode. At the time of interview, 3 children (5.3%) had moderate chronic neuropathic (burning) pain on surgical scar. There was no statistically significant difference between the type of anesthesia and the incidence and severity of acute post-operative pain. Despite its limitations, this study confirms the low incidence of chronic post-thoracotomy pain syndrome in children.

scholarly journals The Differential Expression of Aqueous Soluble Proteins in Breast Normal and Cancerous Tissues in Relation to Ethnicity of the Patients; Chinese, Malay and Indian

2010 ◽  
Vol 28 (3) ◽  
pp. 149-165 ◽  
Author(s):  
Seng Liang ◽  
Manjit Singh ◽  
Lay-Harn Gam
Keyword(s):  
Breast Cancer ◽  
Ductal Carcinoma ◽  
Protein Profile ◽  
Female Breast Cancer ◽  
Female Mortality ◽  
Normal Tissues ◽  
Infiltrating Ductal Carcinoma ◽  
Female Breast ◽  
Proteomic Approach ◽  
Breast Tissues

Female breast cancer is one of the leading causes of female mortality worldwide. In Malaysia, breast cancer is the most commonly diagnosed cancer in women. Of the women in Malaysia, the Chinese have the highest number of breast cancer cases, followed by the Indian and the Malay. The most common type of breast cancer is infiltrating ductal carcinoma (IDC). A proteomic approach was applied in this study to identify changes in the protein profile of cancerous tissues compared with normal tissues from 18 patients; 8 Chinese, 6 Malay and 4 Indian were analysed. Twenty-four differentially expressed hydrophilic proteins were identified. We evaluated the potential of these proteins as biomarkers for infiltrating ductal carcinoma based on their ethnic-specific expressions. Three of the upregulated proteins, calreticulin, 14-3-3 protein zeta and 14-3-3 protein eta, were found to be expressed at a significantly higher level in the cancerous breast tissues when compared with the normal tissues in cases of infiltrating ductal carcinoma. The upregulation in expression was particularly dominant in the Malay cohort.

A Case of a Giant Borderline Phyllodes Tumor Early in Pregnancy Treated with Mastectomy and Immediate Breast Reconstruction

2016 ◽  
Vol 22 (6) ◽  
pp. 683-687 ◽  
Author(s):  
Lori F. Gentile ◽  
William Foster Gaillard ◽  
Jodi-Ann Wallace ◽  
Lisa R. P. Spiguel ◽  
Layla Alizadeh ◽  
...  
Keyword(s):  
Breast Reconstruction ◽  
Phyllodes Tumor ◽  
Immediate Breast Reconstruction ◽  
In Pregnancy

Thoracic Epidural Anesthesia Combined with General Anesthesia: The Preferred Anesthetic Technique for Thoracic Surgery

2001 ◽  
Vol 92 (4) ◽  
pp. 848-854 ◽  
Author(s):  
Vera Von Dossow ◽  
Martin Welte ◽  
Ulrich Zaune ◽  
Eike Martin ◽  
Michael Walter ◽  
...  
Keyword(s):  
Thoracic Surgery ◽  
General Anesthesia ◽  
Epidural Anesthesia ◽  
Thoracic Epidural Anesthesia ◽  
Anesthetic Technique ◽  
Thoracic Epidural

Paraplegia from Spinal Cord Injury After Thoracic Epidural Catheterization Performed Under General Anesthesia

2006 ◽  
Vol 103 (2) ◽  
pp. 513 ◽  
Author(s):  
Yoshitaka Takii ◽  
Koki Sunouchi ◽  
Masao Tadokoro ◽  
Yujiro Murata ◽  
Yoshiko Unno ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
General Anesthesia ◽  
Thoracic Epidural ◽  
Cord Injury ◽  
Epidural Catheterization

scholarly journals In Silico Study on Tumor-Size-Dependent Thermal Profiles inside an Anthropomorphic Female Breast Phantom Subjected to Multi-Dipole Antenna Array

2020 ◽  
Vol 21 (22) ◽  
pp. 8597
Author(s):  
Piotr Gas ◽  
Arkadiusz Miaskowski ◽  
Mahendran Subramanian
Keyword(s):  
Tumor Size ◽  
Breast Tumor ◽  
In Silico ◽  
Dipole Antenna ◽  
Input Power ◽  
Hyperthermia Treatment ◽  
Female Breast ◽  
Breast Phantom ◽  
Breast Tissues ◽  
Dipole Sources

Electromagnetic hyperthermia as a potent adjuvant for conventional cancer therapies can be considered valuable in modern oncology, as its task is to thermally destroy cancer cells exposed to high-frequency electromagnetic fields. Hyperthermia treatment planning based on computer in silico simulations has the potential to improve the localized heating of breast tissues through the use of the phased-array dipole applicators. Herein, we intended to improve our understanding of temperature estimation in an anatomically accurate female breast phantom embedded with a tumor, particularly when it is exposed to an eight-element dipole antenna matrix surrounding the breast tissues. The Maxwell equations coupled with the modified Pennes’ bioheat equation was solved in the modelled breast tissues using the finite-difference time-domain (FDTD) engine. The microwave (MW) applicators around the object were modelled with shortened half-wavelength dipole antennas operating at the same 1 GHz frequency, but with different input power and phases for the dipole sources. The total input power of an eight-dipole antenna matrix was set at 8 W so that the temperature in the breast tumor did not exceed 42 °C. Finding the optimal setting for each dipole antenna from the matrix was our primary objective. Such a procedure should form the basis of any successful hyperthermia treatment planning. We applied the algorithm of multi for multi-objective optimization for the power and phases for the dipole sources in terms of maximizing the specific absorption rate (SAR) parameter inside the breast tumor while minimizing this parameter in the healthy tissues. Electro-thermal simulations were performed for tumors of different radii to confirm the reliable operation of the given optimization procedure. In the next step, thermal profiles for tumors of various sizes were calculated for the optimal parameters of dipole sources. The computed results showed that larger tumors heated better than smaller tumors; however, the procedure worked well regardless of the tumor size. This verifies the effectiveness of the applied optimization method, regardless of the various stages of breast tumor development.

Aggressive malignant phyllodes tumor of breast with omental metastases – A case report

2021 ◽  
Vol 40 (4) ◽  
pp. 287-291
Author(s):  
B. Rajkrishna ◽  
Rajesh Balakrishnan ◽  
Mithun Raam ◽  
A. Santhosh Raj ◽  
Patricia Sebastian ◽  
...  
Keyword(s):  
Radical Mastectomy ◽  
Phyllodes Tumor ◽  
Distant Metastases ◽  
Left Breast ◽  
Adjuvant Radiation ◽  
Left Chest ◽  
Dismal Prognosis ◽  
Phyllodes Tumour ◽  
Flap Cover ◽  
Malignant Phyllodes Tumour

Distant metastasis from malignant Phyllodes tumour (PT) is rare. They generally metastasize to the lung, bone, pleura, and liver. We present a very rare case of a 25-year-old woman with intraabdominal metastases from malignant phyllodes tumour of the breast. She presented with left breast lump and the biopsy was Phyllodes tumour. She underwent a two staged surgery; left modified radical mastectomy followed by left latissimus dorsi musculocutaneous flap cover. She received adjuvant radiation therapy to left chest wall. Following which she developed intrabdominal mass which was proven to be metastasis from Phyllodes tumour. She was then advised palliative chemotherapy. Malignant Phyllodes with distant metastases has a dismal prognosis. We propose it is preferable to have a CT Thorax and Abdomen as a staging workup for patients with malignant PT to identify those with poor prognosis.

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