“ROLE OF AUTOLOGOUS PLATELET RICH PLASMA THERAPY IN TREATMENT OF PLANTAR FASCIITIS, A PROSPECTIVE STUDY.”

Plantar fasciitis is fairly common in orthopaedics out-patient department. Although, majority of the patients do well with conservative treatment, some patients continue to have painful feet despite a course of conservative management. These patients of plantar fasciitis are provided with other treatment modalities such as local corticosteroid but the chronic condition requires multiple dosages and are associated with adverse reaction. Autologous platelet rich plasma therapy is another modality for treatment of such cases and are not associated with adverse effects when compared with corticosteroid injection therapy. This prospective case series analyses the improvement of pain using visual analogue scale of plantar fasciitis patients treated with autologous platelet rich plasma over the course of 3 months. 30 patients were enrolled in the study. The mean VAS score at pre injection was 7.13 which signicantly reduced to 3.3 at 6 weeks post injection and 2.36 at 6 weeks post injection. There was signicant improvement in pain. This study is limited with small sample size and short follow up.

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Long-term clinical results of autologous Platelet Rich Plasma (PRP) in recalcitrant plantar fasciitis

IP International Journal of Orthopaedic Rheumatology ◽

10.18231/j.ijor.2021.004 ◽

2021 ◽

Vol 7 (1) ◽

pp. 12-16

Author(s):

Ankit Kumar Garg ◽

Ranjeet Choudhary ◽

Alok Chandra Agrawal ◽

Anupam Pradip Inamdar ◽

Shilp Verma

Keyword(s):

Plantar Fasciitis ◽

Platelet Rich Plasma ◽

Post Injection ◽

Duration Of Symptoms ◽

Low Level ◽

Autologous Platelet Rich Plasma ◽

The Mean ◽

One Year ◽

Autologous Platelet

In recent years, biologic therapies such as platelet-rich plasma (PRP) have gained prominence in multiple orthopedics degenerative tendinopathy and ligamental pathology. This research aimed to assess the clinical effectiveness of autologous platelet-rich plasma injection in cases of recalcitrant plantar fasciitis (RPF) over a long period.A prospective observational study was performed on RPF that did not experience pain relief after three months of conservative therapy. Under sterile conditions, inject approximately 3ml of platelet-rich plasma mixed with 0.5ml lignocaine into the maximum tender point of the heel. Visual Analogue Score for Pain, the American Orthopedics Foot, and Ankle Society (AOFAS) Ankle, and Hind Foot Score at one month, three months, six months, one year, and two years after injection.A total of 60 patients of RPF which 23 (38.33%) were male, and the rest 37 (61.66%) were female. The mean age was 45 ± 7.25 and the mean duration of symptoms was 7.4 ± 2.1months. The mean VAS score was 7.92 ± 1.2 at pre-injection, was progressively reduced post-injection to 5.61 ± 1.56 at one month, 3.1 ± .83 at three months, and 2.4 ± .68 at six months and remained at low level 2.5 ± .92 at one year and 2.7 ± .56 at two years. The mean AOFAS score was 56.92 ± 13.24 at pre-injection, was progressively increased post-injection to 66.41± 10.26 at one month, 78.31 ± 12.64 at three months, and 90.54 ± 10.71 at six months and remained at a low level 89.24 ± 8.92 at one year and 87.54 ±10.56 at two years. Mean VAS and AOFAS scores showed statistically significant pain reduction and functional improvements at successive follow-ups till 6month (p<.05); the improvement remained stable and did not change significantly until the last appointment at 2year follow-up (p > 0.05).The outcomes of autologous PRP injection in recalcitrant plantar fasciitis are reliable, stable, and predictable in both long- and short-term follow-up. PRP injection is safer and not associated with serious complications as in the case of steroid injection.

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Autologous platelet rich plasma versus corticosteroid injection for chronic plantar fasciitis: a prospective controlled randomized comparative clinical study

International Journal of Research in Medical Sciences ◽

10.18203/2320-6012.ijrms20181430 ◽

2018 ◽

Vol 6 (5) ◽

pp. 1594 ◽

Cited By ~ 1

Author(s):

Sachin Upadhyay ◽

Vijendra Damor

Keyword(s):

Plantar Fasciitis ◽

Platelet Rich Plasma ◽

Corticosteroid Injection ◽

Primary Objective ◽

Control Group ◽

Base Line ◽

Autologous Platelet Rich Plasma ◽

American Orthopaedic ◽

Autologous Platelet

Background: Primary objective was to evaluate and compare the effectiveness of autologous platelet rich plasma (PRP) and steroid injections in chronic cases of plantar fasciitis.Methods: The present study was a prospective cohort study; 140 consecutive patients with chronic plantar fasciitis were enrolled and randomized in two groups: One receives the Platelet rich plasma (PRP) therapy (study group) and another receiving corticosteroid injection (control group). The outcomes in both groups are then evaluate and compared using visual analogue scale (VAS) and American Orthopaedic foot and Ankle Society (AOFAS) scale at 1month, 3month and 6 month post injection. The level of significance was set at p <0.05.Results: Prospective data was collected of 140 heels. The average follow up duration was about 6 months. The score on VAS scale and AOFAS improved from base line for both group but the patients received PRP therapy had a statistically significant (p<0.05) reduction in pain and improved AOFAS score at last follow up. No adverse complications were reported.Conclusions: The result of present study showed that the PRP therapy has potential to reduce pain and improve the functional outcome in cases of chronic planter fasciitis. It was found to be more effective and significantly better than corticosteroid injection.

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Successful Management of Treatment-Resistant Alopecia Areata with Platelet Rich Plasma: A Case Series

Serbian Journal of Dermatology and Venerology ◽

10.2478/sjdv-2019-0007 ◽

2019 ◽

Vol 11 (2) ◽

pp. 50-52

Author(s):

Sanjeewani Fonseka ◽

Y.M.D.M Bandara ◽

Brabaharan Subhani

Keyword(s):

Alopecia Areata ◽

Platelet Rich Plasma ◽

Case Reports ◽

Immunosuppressive Agents ◽

Case Series ◽

Treatment Resistant ◽

Successful Management ◽

Autologous Platelet Rich Plasma ◽

Dermal Injection ◽

Autologous Platelet

Abstract Introduction. Alopecia areata (AA) is an autoimmune disease-causing non-scarring alopecia. It is usually treated with immunosuppressive agents, to which some patients fail to respond adequately. Material and Methods. Three patients with AA refractory to standard therapy were treated with intra-dermal injection of autologous platelet rich plasma (PRP) every four weeks. Results. All three patients showed remarkable improvement after multiple sessions of PRP treatment. Conclusion. Autologous PRP is safe and effective in treatment-resistant forms of AA demonstrated in many case reports; therefore it deserves further study with randomized, placebo-controlled trials.

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