scholarly journals QUALITY OF LIFE OF PATIENTS UNDERGOING SURGICAL TREATMENT OF LOWER LIMB CANCER

Author(s):  
Maria Iakovleva ◽  
◽  
Olga Shchelkova ◽  
Ekaterina Usmanova ◽  
◽  
...  

"Patients suffering from oncological diseases are the focus of attention of both physicians and psychologists. Although tumor lesions of bones and soft tissues are a relatively rare condition, its effect on the person’ mind and lifestyle are significant, and its treatment is a challenge, also in terms of patient’s adaptation to the disease and therapy. There are various strategies for treating this pathology; all of them are associated with high-tech medicine focused on maintaining or improving patients’ quality of life (QoL). The aim of the present research is to study the psychological characteristics and QoL of patients undergoing surgical treatment of tumor lesions of bones and soft tissues of lower limbs. Material and methods. 36 patients were examined (mean age 58,22; 19 – men). The SF-36 questionnaire, Ways of Coping Questionnaire (WCQ), and Big Five Personality Test (BFI) were used. Treatment by means of the isolated limb perfusion technique was prescribed to 15 patients (group 1); 21 patients were subjected to lower limb amputation due to their disease (group 2). Results. It was found that patients who underwent amputation are characterized by lower rates on the coping scale ‘accepting responsibility’ than patients from the perfusion group (p < 0.05); at the same time, patients from the second group had higher values on the ‘openness’ scale of the BFI compared to the first group (p < 0.1). The study of the relationship between patients’ QoL parameters, personality and coping showed that in the first group the values on the coping scale ‘seeking social support’ negatively correlate with ‘bodily pain’ (p < 0.01), and ‘escape–avoidance’ negatively correlates with ‘social functioning’ (p < 0.01). In the second group, the following significant correlations between personality traits and QoL were revealed: ‘extraversion’ is positively associated with ‘physical functioning’, ‘role-emotional’ and ‘mental health’ (p < 0.01), ‘agreeableness’ has a negative correlation with ‘bodily pain’ and ‘general health’ (p < 0.01), ‘neuroticism’ is negatively related with ‘bodily pain’ and ‘general health’ (p < 0.01), ‘openness’ is positively associated with ‘bodily pain’ and ‘general health’ (p < 0.01). Conclusion. The data obtained emphasizes the importance of taking into account personality characteristics in the management of patients with cancer, including tumor lesions of the bones and soft tissues, as well as the dynamic nature of QoL and its close interconnection with the stage and strategy of treatment and patients’ personality. Psychological support for patients is required for their successful adaptation to the illness and therapy. Acknowledgement. This research was supported by the Russian Foundation for Basic Research (RFBR) (Grant No 20-013-00573)."

2020 ◽  
Vol 79 (Suppl 1) ◽  
pp. 466.1-467
Author(s):  
B. Gavilán Carrera ◽  
I. C. Alvarez-Gallardo ◽  
M. Borges Cosic ◽  
A. Soriano Maldonado ◽  
M. Delgado-Fernández ◽  
...  

Background:Optimizing the highly deteriorated quality of life (QoL) of patients with fibromyalgia is one of the main goals in the management of the disease1. Physical fitness has been identified as a powerful marker of health that is positively related to QoL in this population2, although previous evidence is mainly based on cross-sectional data.Objectives:This study aimed to examine the longitudinal associations (2- and 5-year follow-up) between physical fitness and QoL in women with fibromyalgia.Methods:In this prospective cohort study, women diagnosed with fibromyalgia (age: 51.3±7.6 years) with completed data were included at baseline (n=441), at 2-year follow-up (n=220) and at 5-year follow-up (n=227). The Senior Fitness Tests battery was used to assess physical fitness components and a standardized global fitness index was calculated. The eight dimensions plus the two physical and mental component summaries of the Short-Form health survey-36 questionnaire were used to assess QoL. To examine whether changes in fitness predicted QoL at follow-up, multiple linear regression models were built. The bidirectionallity of the associations (whether changes in QoL predicted fitness at follow-up) was also tested. Outcome values at baseline and age, fat percentage, analgesic consumption, educational level, and occupational status at follow-up were entered as potential confounders in all analyses.Results:Changes in fitness were associated with physical function (β=0.160), physical role (β=0.275), bodily pain (β=0.271), general health (β=0.144), and physical component summary (β=0.276) at 2-year follow-up (all,P<0.05) and with changes in physical role (β=0.215) and physical component summary (β=0.135) at 5-year follow-up (all,P<0.05). Changes in physical function (β=0.165), physical role (β=0.230), bodily pain (β=0.230), general health (β=0.130) and physical summary component (β=0.251) were associated with fitness at 2-year follow-up (all,P<0.05). Changes in all dimensions of QoL (β rating from 0.113 to 0.198), as well as the physical (β=0.174) and mental (β=0.164) summary components were associated with fitness at 5-year follow-up (all,P<0.05).Conclusion:Increasing levels of physical fitness over time predicts future QoL in women with fibromyalgia, especially for physical domains at 2-year follow-up. In addition, increasing QoL across all domains over time predicts future global fitness at 2- and, specially, 5-year follow-up. Future research is warranted to determine the clinical relevance of the bidirectional association between physical fitness and QoL in fibromyalgia.References:[1]Macfarlane GJ, et al. Ann Rheum Dis, 2018; 76(2), 318-328.[2]Álvarez-Gallardo IC, et al. 2019;99:1481–1494.Acknowledgments:This study was supported by the Spanish Ministry of Economy and Competitiveness (I+D+i DEP2010-15639; I+D+I DEP2013-40908-R; BES-2014-067612) and the Spanish Ministry of Education (FPU14/FPU 15/00002)Disclosure of Interests: :None declared


2019 ◽  
Vol 21 (1) ◽  
pp. 33-40
Author(s):  
Marilia de Andrade Fonseca ◽  
Amanda Gilvani Cordeiro Matias ◽  
Maria de Lourdes de Freitas Gomes ◽  
Marcos Almeida Matos

Background. Lower limb fractures are associated with severe disability, prolonged treatment and recovery time, and account for the greatest number of surgical procedures. Studies focusing on the health related quality of life (HRQOL) of patients who sustained lower limb fractures at a productive age are still scarce. The aim of the present study was to assess the HRQOL of individuals who sustained lower limb fractures at two time points: during the acute trauma period (hospitalization) and after six months. Materials and methods. A prospective observational longitudinal study was conducted including a total of 121 patients aged 18 years or older with fractures in the lower limbs evaluated based on clinical and sociodemographic variables and using the HRQOL questionnaire SF-36. The data were collected from referral trauma hospitals in two stages: during hospitalization (in-hospital period) and from the same individuals six months after the first interview. Results. At six months following the trauma, significant differences were found for the domains of functional capacity (from 2.77±7.82 to 51.11±28.43), pain (47.51±35.51 to 74.29±21.63), and emotional impairment (57.01±47.62 to 91.22±22.92) in the study period. However, no improvement was observed in the domains of physical limitations and social aspects. There was significant association for the domain “Pain” with age, level of education, and rehabilitation; the domain “Emotional impairment” was associated with treatment within 10 hours, level of education, and immediate osteosynthesis. At six months, only functional capacity exhibited significant associations with the level of education and rehabilitation. Conclusion. Lower limb fractures have a negative impact on the HRQOL that persists for at least six months after the traumatic event and is reflected in the psychosocial, physical and emotional burden imposed by the trauma.


10.12737/6454 ◽  
2014 ◽  
Vol 8 (1) ◽  
pp. 0-0
Author(s):  
Антонов ◽  
A. Antonov

Use elixir Altai (&#34;Vitavis&#34;) in combination with ion-activated with water by means of such a complex contingent cancer patients as patients with metastatic bone fractures of the upper and lower limbs can reduce the early postoperative period, and to reduce to a minimum infectious complications and improve quality of life. The problem of postoperative complications, until now, is not solved. In oncologic patients, and those more in by III and As IV stages occurs it immunnodefitsit, which is caused not only by basic disease, but also by conse-quences of khimio- beam therapy. In connection with this appears the difficulty in the surgical treatment, caused by postoperative complications. As a result surgical treatment appears surgical injury, oxidizing stress, disturbance of homeostasis and oppression of immunity, which leads to an even larger disturbance of immunity in oncologic patients, which decreases the unspecific resistibility of organism. The application of adaptogena of the elixir of Altai (“Vitavis”) in combination with the ionic- activated aqueous means makes it possible to level and to reduce on no oxidizing stress, to increase the unspecific resistibility of the organism of oncologic patient and to increase immuni-ty. Moreover, powerful antioxidant - the ionic- activated aqueous means strengthens the action of adaptogena of the elixer of Altai (“Vitavis”), which leads to the decrease of postoperative infectious complications, reduces postoperative period, improves the quality of life and enlarges indications to the surgical treatment in oncologic patients with III it and IV by the stages of diseases.


2021 ◽  
Vol 24 (1) ◽  
pp. 61-67
Author(s):  
Aleksandr N. Kosenkov ◽  
Ivan A. Vinokurov ◽  
Anastasia K. Kiselea ◽  
Svetlana V. Udovichenko

Today, there are several approaches to the treatment of critical lower limb ischemia (KINK). However, despite the high clinical effectiveness achieved, it is not always possible to achieve a high quality of life for the patient after surgery. This article presents modern aspects of surgical treatment of KINK and assesses the quality of life of patients depending on the type of intervention (literature review).


Author(s):  
Burcu Burçak ◽  
Bilge Kesikburun ◽  
Belma Füsun Köseoğlu ◽  
Öznur Öken ◽  
Asuman Doğan

Author(s):  
Karla A. Camarillo–Gómez ◽  
Gerardo I. Pérez-Soto ◽  
Luis A. Torres-Rico

In this paper, a lower limb orthosis is proposed to form the human gait neuromuscular patterns in patients with myelomeningocele. The orthosis has two lower limbs of 2–DOF each which reduces the motion of the hip and knee to the sagittal plane. The orthosis are assembled in a back support which also supports the patients weight. The control system for the orthosis allows to reproduce in a repetitive, controlled and autonomous way the human gait cycle at different velocities according to the patient requirements; so that, the neuromuscular patterning can be supervised by a therapist. The development of these orthosis seeks to improve the quality of life of those infants with myelomenigocele and to introduce a lower cost Mexican technology with Mexican anthropometric dimensions.


2021 ◽  
Vol 11 (4) ◽  
pp. 30-35
Author(s):  
Vladlen V. Bazylev ◽  
Evgeniy V. Nemchenko ◽  
Galina N. Abramova ◽  
Tаtyana V. Kanaeva ◽  
Vаdim A. Karnakhin

Aim. To evaluate long-term quality of life (QOL) of patients after surgical treatment of mitral valve disease depending on the types of surgical intervention, to identify predictors of a lower QOL after surgery. Material and methods. A single-center retrospective study involved 107 patients after isolated correction of primary non-ischemic mitral valve (MV) pathology, who were operated on from 2009 to 2016, and analyzed their long-term QOL. The follow-up period was from 2 to 6 years. 2 groups of patients were formed: the 1st group (n=60) patients who underwent mitral valve replacement (MVR); the 2nd group (n=47) patients who underwent mitral valve repair (MVRep). There were no statistically significant differences between the main clinical and demographic characteristics in reference to the groups. The SF-36 questionnaire was used for studying QOL. Results. The indicators of QOL approach the average population levels in both groups. In group MVRep Physical Functioning PF (p=0.02 and 0.01), Bodily Pain BP (p=0.04), Vitality VT (p=0.01) and Social Functioning SF (p=0.001) are higher. There are improvements in physical and mental health components after surgery. Mental and physical components are lower than in the normal population but they dont go beyond average populations indicators. Mental health in the MVRep group is better than in the MVR group (p=0.01). Female gender, dilatation of the left atrium (every 1 mm before surgery), older age (every year) increased the probability of lower QOL in the long term by 84, 11 and 8% respectively. Conclusion. Long-term QOL of patients after surgical treatment of mitral valve disease improves both after valve repair and after valve replacement. After MVRep Physical Functioning, Bodily Pain, Vitality and Social Functioning indicators are higher. There are improvements in physical and mental health components. Psychological component of health is higher in patients in the MVRep-group. Female gender, dilatation of the left atrium, older age increase the probability of lower QOL in the long term after mitral valve surgery.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Nuria Sarroca ◽  
José Valero ◽  
Javier Deus ◽  
Josefa Casanova ◽  
María José Luesma ◽  
...  

AbstractAmputation represents a drastic impact on the patient’s body and perception. This cross-sectional study aims to analyse the aesthetic concern represented by body image, self-esteem and quality of life in patients with unilateral transtibial amputations of lower limbs compared to control group. People living with amputations present lower average levels than controls in all subscales of the SF-36 (Short Form 36 Health Survey) quality of life questionnaire, and in both the physical component summary and the mental component summary, although the difference is not statistically significant in the latter. These patients present a significantly lower mean score (p = 0.002) in the MBSRQ (Body-Self Relations Questionnaire) body image questionnaire: 2.64 ± 0.49 opposed to 3.16 ± 0.55 in controls. People living with amputations had a lower mean score on the Rosenberg Self-Esteem scale than controls (34.44 ± 4.61 v 36.04 ± 3.63). The results also show that amputation has a significant influence on the BI (Body image) of patients with unilateral transtibial amputations. SE (Self-Esteem) seems to be an aspect that is not significantly affected by lower limb amputation, although these patients scored a lower mean on the RSE scale compared to the control group. We consider it is highly relevant to assess QoL (Quality of life), BI and SE in patients after a lower limb amputation process.


2017 ◽  
Vol 12 (1) ◽  
Author(s):  
Marta Lisnawati Zalukhu ◽  
Rizaldy Taslim Pinzon ◽  
Kadek Sinthia Grahita Adnyana

AbstractNeuropathy is one of the most common complications in patients with diabetes mellitus (DM). Neuropathy has contributed to some impacts of quality of life (QOL), general health status, and socio-economy level. Therefore, it is important to understand more about this issue, so appropriate treatment could be taken to improve QOL of patients with diabetic neuropathy. This study aimed to measure the profile of a patient’s life quality in DM with neuropathy. This study was a observational study using Short Form 8 (SF-8) Health Survey Standard Indonesia to measure the QOL in patients with diabetic neuropathy that were treated consecutively from March to August 2016 in the Department of Neurology in Bethesda Hospital, Yogyakarta. Fifty seven patients with diabetic neuropathy were enrolled as subjects in this study. Most of them were women (52,6%). The mean age of subjects was 57.3 ± 5.85 years. The lowest QOL score in patients with diabetic neuropathy were observed in general health perceptions category (45.26%), followed by bodily pain (57.19%), vitality or energy (69.12%), physical functioning (69.82%), social role functioning (74.03%), mental health (78.59%), physical role functioning (80.70%), and emotional role functioning (81.05%). Patients with diabetic neuropathy have poor QOL. Sex and age were not significantly related to the QOL in patients with diabetic neuropathy. AbstractNeuropati merupakan salah satu komplikasi tersering pada diabetes melitus (DM). Neuropati dapat memengaruhi kualitas hidup, derajat kesehatan, maupun tingkat ekonomi. Oleh karena itu, penting untuk mengetahui kualitas hidup pasien DM dengan neuropati beserta dampak yang ditimbulkannya terlebih dahulu agar mendapatkan penanganan yang tepat demi meningkatkan kualitas hidup pasien. Penelitian ini bertujuan untuk mengetahui profil kualitas hidup pasien DM dengan neuropati. Penelitian ini merupakan studi observasional menggunakan Short Form 8 (SF-8) Health Survey Standard Indonesia terhadap pasien diabetes melitus dengan neuropati yang diambil secara konsekutif pada bulan Maret hingga Agustus 2016 di Poli Saraf Rumah Sakit Bethesda, Yogyakarta. Terdapat 57 subjek yang dimasukkan dalam penelitian ini. Sebanyak 52,6 % di antaranya adalah perempuan dengan rerata usia 57,3 ±5,85 tahun. Skor kualitas hidup pasien neuropati DM yang paling rendah terdapat pada kategori kesehatan umum (45,26%) disusul nyeri pada tubuh (57,19%), vitalitas atau energi (69,12%), fungsi fisik (69,82%), fungsi sosial (74,03%), kesehatan mental (78,59%), kemampuan peran dengan masalah kesehatan fisik (80,70%), dan kemampuan peran dengan masalah emosi (81,05%). Jenis kelamin dan usia tidak berhubungan secara signifikan terhadap kualitas hidup pasien DM dengan neuropati.


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