scholarly journals A Correlation Study on Serum Prostate Specific Antigen Levels and Gleason Grading In Transrectal Ultrasound Guided Prostatic Biopsies-A Tertiary Care Hospital Experience

2020 ◽  
Vol 08 (02) ◽  
pp. 495-498
Author(s):  
Poorana Priya. P ◽  
Yegumuthu K
2020 ◽  
Vol 58 (221) ◽  
Author(s):  
Robin Joshi

Introduction: Transrectal ultrasound of prostate provides better visual for biopsy. Transrectalultrasound guided prostate biopsy is usually performed in men with an abnormal digital rectalexamination, and elevated prostate specific antigen (>4ng/ml) or prostate specific antigen velocity(rate of prostate specific antigen change) i.e., >0.4-0.75ng/ml/year. The aim of the study is to find outthe complications of transrectal ultrasound guided prostatic biopsies. Methods: This descriptive cross-sectional study was done among 50 patients who transrectalultrasound guided prostatic biopsies in a tertiary care hospital, from July 2017 to July 2019 afterreceiving ethical approval from the Institutional Review Committee of Kathmandu MedicalCollege and teaching hospital. Convenient sampling was done. All patients were informed aboutthe potential benefits and risks of the transrectal ultrasound guided prostate biopsy and patientssigned an informed written consent form. Statistical analysis was done by using Statistical Packagefor Social Sciences version 16. Results: Mean prostate specific antigen was 34.571 and mean weight of prostate was 44.6gm.Moderate to severe pain was experienced by 15 (30%), 2 (4%) had hematuria with fever accountingfor 3 (6%) patients. All were managed conservatively with no mortality related to the procedure andcomplication. Three patients was positive for malignancy on re-biopsy. Conclusions: Transrectal ultrasound guided biopsy of prostate is a pioneer experience in Nepal. Ithas proved to be an useful tool of diagnosis of suspected carcinoma of Prostate. Use of neurovascularblock may reduce the pain during the procedure.  


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