Treatment of Entropion – A modified Technique

Purpose: To study the results of a modified technique of Entropion correction at a Tertiary care hospital.Study Design: Quasi experimental study.Place and Duration of Study: Layton Rahmatullah Benevolent Trust (LRBT), a tertiary care teaching Eyehospital, Korangi, Karachi, for a duration of six months, from January 2018 to June 2018.Material and Methods: Patients with senile entropion were included in the study. Patients with recurrententropion, cicatricial entropion, chronic/acute ocular and adnexal infection were excluded. Three equally spaceddouble-armed 6–0 vicryl horizontal mattress sutures were used to close the skin and orbicularis muscle of thewound with a bite of the retractors in the center and a 5 mm silicone tube bolster place in the superior loop. Postoperativetreatment of antibiotics, anti-inflammatory drugs and topical lubricant eye gel were given. Patients wereexamined on 11stpost operative day and then weekly interval for up to one month and thereafter every month forup to six months.Results: There were 40 eyes of 30 patients with ages ranging from 50 to 65 years. Twenty (66%) patients hadunilateral repair and 10 (33%) had bilateral repair done. No recurrence was seen in 39 (97.5%) eyes at the endsix months after surgery. Out of the 40 patients, only 2 (5%) patients complained of heaviness which went awayeventually with the disintegration of the external tamponade.Conclusion: This modified technique of entropion repair using skin excision with retractor plication in the woundhas a favorable outcome with minimum recurrences and complications.

Download Full-text

A Study of Prescribing Patterns for Non-Steroidal Anti-Inflammatory Drugs in a Tertiary Care Teaching Hospital

10.36468/pharmaceutical-sciences.774 ◽

2021 ◽

Author(s):

GEETHA KANDASAMY ◽

DALIA ALMAGHASLAH ◽

MONA ALMANASEF ◽

RAJALAKSHIMI VASUDEVAN ◽

ALI ALQAHTANI ◽

...

Keyword(s):

Teaching Hospital ◽

Tertiary Care ◽

Prescribing Patterns ◽

Tertiary Care Teaching Hospital ◽

Care Teaching ◽

Inflammatory Drugs ◽

Anti Inflammatory

Download Full-text

Safety reporting study of nonsteroidal anti-inflammatory drugs in a tertiary care teaching hospital, SIMS, Uttar Pradesh

International Journal of Basic & Clinical Pharmacology ◽

10.18203/2319-2003.ijbcp20204093 ◽

2020 ◽

Vol 9 (10) ◽

pp. 1544

Author(s):

Saborni Dey ◽

Harsh Kumar ◽

Anand Kumar Shukla

Keyword(s):

Adverse Drug Reactions ◽

Diclofenac Sodium ◽

Tertiary Care ◽

Uttar Pradesh ◽

Drug Reactions ◽

Care Teaching ◽

Safety Reporting ◽

Inflammatory Drugs ◽

Anti Inflammatory ◽

Probable Type

Background: The nonsteroidal anti-inflammatory drugs (NSAIDs) are among the most frequently used drugs to treat pain and inflammation. Although NSAIDs are having enormous clinical use, but are not devoid of adverse drug reactions (ADRs) as peptic ulcer, gastritis, renal, neurological reactions etc. So, this pilot study is intended to assess the incidence and pattern of ADRs of the NSAIDs in a tertiary care teaching hospital.Methods: Total 600 Orthopaedic out-patients of SIMS, Hapur were enrolled in the study to observe the risk of ADRs due to NSAIDs. All the ADRs were further analysed in relation to age, sex, types of drug and its pattern etc. The causality was analysed by using Naranjo’s Algorithm and severity was analysed by using the Hartwing and Siegel scale.Results: Out of the 600 patients with NSAID therapy, 35 patients (5.83%) experienced total 10 types of ADRs. The adverse drug reactions observed by the patients were gastric symptoms, headache, urticaria, oedema etc. The most frequently observed ADR was gastritis. With all the prescribed drugs Tab Diclofenac sodium accounted for 57.14% and Paracetamol for 11.42% of all the ADRs. According to Naranjo’s Algorithm 62.87% ADRs were possible’ and 37.14% were of probable type and ADRs were mostly mild in severity.Conclusion: In this study, incidence of adverse reactions to nonsteroidal anti-inflammatory drugs was 5.83 and the most common implicated drug for the ADRs were Diclofenac sodium. Most of the adverse effects were mild and tolerable.

Download Full-text