RESULTS OF COMBINED PHOTOTHERAPY WITH BLUE LIGHT IN THE COMPLEX TREATMENT OF PATIENTS WITH PRIMARY OPEN ANGLE GLAUCOMA

Introduction. Glaucoma is one of the most significant eye diseases. It is often diagnosed, not always amenable to therapy, and can lead to a complete loss of visual functions. In recent years, the method of osteopathic correction has become widespread as one of the effective methods of treatment and rehabilitation of patients with pathologies of various body systems. In the pathogenesis of glaucoma, it is customary to distinguish a dystrophic concept, which considers primary open-angle glaucoma as a result of dystrophic changes in the connective tissue, as well as in the endothelial lining of the trabeculae and Schlemm′s canal, especially destructive changes in mitochondria and the alteration of their functional activity. A vascular concept is also distinguished. According to this concept, the central link in the pathogenesis of glaucoma is circulatory disorder in the ciliary vessels, ocular artery, and major vessels of the head and neck, it can be assumed that osteopathic correction in the treatment of patients with open-angle glaucoma will be pathogenetically substantiated and will have a positive effect on intraocular pressure and trophicity of the optic nerve. The goal of research — to study the influence of in osteopathic correction on the nature of unoperated glaucoma (stage IIA) and to substantiate the possibility of using osteopathic correction in the complex treatment of patients with this pathology.Materials and methods. A prospective controlled randomized study was conducted at 52 city polyclinics, branch 3, Moscow, from January 2018 to January 2019. 40 patients (70 eyes) aged 50 to 75 years with primary open-angle glaucoma IIA stage were examined. At this stage of the disease, patients most often seek medical care and the issue of conservative management is primarily considered. All patients were divided into two groups of 20 people: the main group and the control group. The treatment in the main group included hypotensive drug therapy and osteopathic correction. Patients of the control group received only drug therapy. All patients underwent ophthalmic (visometry, tonometry, perimetry) and osteopathic examination twice: before the treatment and after 3 months.Results. For patients with primary open-angle IIA non-operated glaucoma, regional (most often regions of the head, neck, dura mater) and local (abdominal diaphragm, iliac bones, hip and knee joints) somatic dysfunctions were the most typical. In the main group a statistically significant decrease in the frequency and severity of dysfunctions at all levels was stated. Also, in patients receiving osteopathic correction, a significant decrease in the level of intraocular pressure and perimetric indices was noted. In patients of the control group, no reliable changes in these indicators were obtained.Conclusion. The results obtained indicate that osteopathic correction is clinically effective in the complex treatment of patients with primary open-angle II A glaucoma.

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Study of the effectiveness of osteopathic correction in the complex treatment of patients with operated primary open-angle glaucoma

Russian Osteopathic Journal ◽

10.32885/2220-0975-2021-3-66-76 ◽

2021 ◽

pp. 66-76

Author(s):

O. V. Zubkov ◽

E. A. Smirnova ◽

V. V. Kramar ◽

O. I. Kurbatov

Keyword(s):

Visual Acuity ◽

Intraocular Pressure ◽

Surgical Treatment ◽

Primary Open Angle Glaucoma ◽

Open Angle Glaucoma ◽

Pain Syndrome ◽

Open Angle ◽

Complex Treatment ◽

Fiber Layer ◽

Complex Therapy

Introduction. Glaucoma is a chronic eye disease characterized by a constant or periodic increase in intraocular pressure, a decrease of visual fields and visual acuity, and by a special form of optic nerve atrophy with excavation in the disc area. The reflection of this slowly fl owing atrophy is a disturbance in the visual field and a complete irreversible loss of visual function. The prevalence of the disease increases with increasing age. The main methods of treatment are medical and surgical. Non-penetrating operations are recognized as the safest methods of surgical treatment of glaucoma. The most common complications of such operations include: detachment of the choroid, small anterior chamber syndrome, hyphema, cicatricial changes in the filtration cushion. Based on the analysis of literature data, it can be assumed that the inclusion of osteopathic correction in the complex therapy of patients with operated glaucoma can increase the effectiveness of therapy.The aim of the research was to study the clinical efficacy of osteopathic correction in the complex treatment of patients operated on primary open-angle glaucoma.Materials and methods. The study involved 20 patients (20 eyes) aged 70 to 75 years with developed and advanced stages of primary open-angle glaucoma, who underwent surgical treatment. The main (10 people) and control (10 people) groups were formed by simple randomization. Participants in the main group received standard medical therapy and osteopathic correction, while participants in the control group received only medical therapy. Changes in the following clinical parameters were evaluated: visual acuity, visual fi eld, intraocular pressure, thickness of the retinal nerve fiber layer, and severity of pain syndrome. Indicators were recorded at the beginning of the study (2 weeks after surgery) and at the end of the study (2–3 months after surgery).Results. Patients receiving osteopathic correction as part of the complex therapy after surgery of primary openangle glaucoma are characterized by a statistically significant (p<0,05) decrease in the severity of pain syndrome, an increase in the magnitude of the visual field and of the thickness of the retinal nerve fiber layer.Conclusion. The obtained results suggest the effectiveness of the inclusion of osteopathic correction in the complex treatment of patients with operated on primary open-angle glaucoma. It is recommended to continue the study with a larger sample size.

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Efficiency evaluation of the neuromidin in complex treatment of the patients with primary glaucoma

Journal of New Medical Technologies eJournal ◽

10.12737/5480 ◽

2014 ◽

Vol 8 (1) ◽

pp. 1-5

Author(s):

Сурнин ◽

S. Surnin ◽

Захарова ◽

Irina Zaharova ◽

Приставка ◽

...

Keyword(s):

Visual Acuity ◽

Primary Open Angle Glaucoma ◽

Open Angle Glaucoma ◽

Nerve Fibers ◽

Field Of View ◽

Control Group ◽

Advanced Stage ◽

Open Angle ◽

Complex Treatment ◽

Severe Degree

The authors studied the efficiency of the Neuromidin in complex treatment of the patients with primary open-angle glaucoma. 65 patients (130 eyes), of which 44 advanced stage, 76 - with severe and 10 eyes with a terminal stage of primary open-angle glaucoma (POAG) were examined. These patients received the Neuromidin in the dose of 1 ml (15 mg) intramuscularly, №10, with complete therapy (the Emoxipin in/m, the Piracetam in/in, the medication parabulbarno). Then, the patients received 1 tablet 2 times daily (20 mg) within 25 days as the monotherapy with local hypotensive drops (timolol, azopt, azarga, fotil, cosopt, alphagan P). Intraocular pressure compensation was achieved by timolol 0,5% dropping (45 eyes), azopt dropping (28 eyes), alphagan P dropping (6 eyes) and by means of combination drugs: azarga (32 eyes), cosopt (15 eyes) and fotil (4 eyes). Of them, in 52 eyes surgical treatment was made. The control group consisted of 30 patients (60 eyes), who received the treatment without the Neuromidin. In work the authors used the standard methods of ophthalmic research. The increase of visual acuity and expansion of field of view in both groups was revealed, but in the patients treated by means of the Neuromidin the visual acuity increased in advanced 0.13, in patients with severe degree of disease – in 0.12, in the control group – in 0.06 and 0,05, respectively . Field of view has expanded in an advanced stage of 55 degrees, and in severe – 35 degrees higher than in the control group. The Neuromidin effect on the state of the outflow of aqueous humor was revealed. This effect can be explained by the fact that the drug stimulates the impulse conduction in nerve fibers and synapses, blocks of cholinesterase, stimulates the ciliary muscle and activation of the outflow watery moisture. The achieved effect gradually decreases to the initial indicators within 6 months in 2/3 patients.

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