scholarly journals Relationship between Methylenetetrahydrofolate Reductase C677T Gene Polymorphism and Autism Susceptibility: A Meta-Analysis

2021 ◽  
Vol 83 ◽  
Author(s):  
Lei Yu Geng ◽  
C. W. Ji ◽  
C. Chen ◽  
P. Huang
Keyword(s):  
Gene Polymorphism ◽  
Methylenetetrahydrofolate Reductase ◽  
Meta Analysis ◽  
Autism Susceptibility

scholarly journals Methylenetetrahydrofolate reductase gene polymorphism as a risk factor for diabetic nephropathy: a meta-analysis

2007 ◽  
Vol 52 (11) ◽  
pp. 881-890 ◽  
Author(s):  
Elias Zintzaras ◽  
Katrin Uhlig ◽  
George N. Koukoulis ◽  
Afroditi A. Papathanasiou ◽  
Ioannis Stefanidis
Keyword(s):  
Risk Factor ◽  
Diabetic Nephropathy ◽  
Gene Polymorphism ◽  
Methylenetetrahydrofolate Reductase ◽  
Meta Analysis ◽  
Reductase Gene ◽  
Methylenetetrahydrofolate Reductase Gene Polymorphism ◽  
Methylenetetrahydrofolate Reductase Gene

scholarly journals Methylenetetrahydrofolate reductase C677T gene polymorphism and essential hypertension: A meta-analysis of 10,415 subjects

2014 ◽  
Vol 2 (5) ◽  
pp. 699-708 ◽  
Author(s):  
KE-MING YANG ◽  
JIAN JIA ◽  
LI-NA MAO ◽  
CHEN MEN ◽  
KANG-TING TANG ◽  
...  
Keyword(s):  
Essential Hypertension ◽  
Gene Polymorphism ◽  
Methylenetetrahydrofolate Reductase ◽  
Meta Analysis

Association between 5,10-Methylenetetrahydrofolate Reductase C677T Gene Polymorphism and Risk of Ischemic Stroke: A Meta-analysis

2016 ◽  
Vol 25 (3) ◽  
pp. 679-687 ◽  
Author(s):  
Yanli Song ◽  
Bohong Li ◽  
Chunjuan Wang ◽  
Penglian Wang ◽  
Xiang Gao ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Gene Polymorphism ◽  
Methylenetetrahydrofolate Reductase ◽  
Meta Analysis

Relationship between methylenetetrahydrofolate reductase (MTHFR) A1298C gene polymorphism and type 2 diabetic nephropathy risk: a meta-analysis

Renal Failure ◽  
2014 ◽  
Vol 36 (6) ◽  
pp. 974-978 ◽  
Author(s):  
Jie Zhang ◽  
Yan Xiao ◽  
Xian-Wen Zhang ◽  
Zhi-Qing Gao ◽  
Jing-Hui Han
Keyword(s):  
Diabetic Nephropathy ◽  
Gene Polymorphism ◽  
Methylenetetrahydrofolate Reductase ◽  
Meta Analysis ◽  
Mthfr A1298c ◽  
Type 2 Diabetic

Methylenetetrahydrofolate Reductase (MTHFЮ Gene Polymorphism (677CT) and Increased Susceptibility to Migraine in Egyptian Population: A Case-Control Study

2019 ◽  
Vol 87 (12) ◽  
pp. 4165-4173
Author(s):  
DOAA M.A. ELZOGHBY, M.D.; MONA M. OSMAN, M.D. ◽  
RANDA M. AMIN, M.D.; HEBA H. ALY, M.D. ◽  
NEHAL E. MAHMOUD, M.D.; DALIA M. ELFAWY, M.D. ◽  
SOMIA ABDELHAMID BAWADY, M.Sc.
Keyword(s):  
Gene Polymorphism ◽  
Methylenetetrahydrofolate Reductase ◽  
Case Control Study ◽  
Case Control ◽  
Egyptian Population ◽  
Control Study ◽  
Increased Susceptibility

Association between ALDH2 Gene Polymorphism and Late-onset Alzheimer Disease: An Up-to-date Meta-analysis

2020 ◽  
Vol 17 (2) ◽  
pp. 105-111
Author(s):  
Haitao Liu ◽  
Wei Ge ◽  
Wei Chen ◽  
Xue Kong ◽  
Weiming Jian ◽  
...  
Keyword(s):  
Gene Polymorphism ◽  
Large Scale ◽  
Late Onset ◽  
Meta Analysis ◽  
Case Control ◽  
Cochrane Library ◽  
Positive Trend ◽  
Case Control Studies ◽  
China National Knowledge Infrastructure ◽  
Aldh2 Gene

Objectives: Previous case-control studies have focused on the relationship between ALDH2 gene polymorphism and late-onset Alzheimer's Disease (LOAD), but no definite unified conclusion has been reached. Therefore, the correlation between ALDH2 Glu504Lys polymorphism and LOAD remains controversial. To analyze the correlation between ALDH2 polymorphism and the risk of LOAD, we implemented this up-to-date meta-analysis to assess the probable association. Methods: Studies were searched through China National Knowledge Infrastructure (CNKI), VIP Database for Chinese Technical Periodicals, China Biology Medicine, PubMed, Cochrane Library, Clinical- Trials.gov, Embase, and MEDLINE from January 1, 1994 to December 31, 2018, without any restrictions on language and ethnicity. Results: Five studies of 1057 LOAD patients and 1136 healthy controls met our criteria for the analysis. Statistically, the ALDH2 GA/AA genotype was not linked with raising LOAD risk (odds ratio (OR) = 1.48, 95% confidence interval (CI) = 0.96-2.28, p = 0.07). In subgroup analysis, the phenomenon that men with ALDH2*2 had higher risk for LOAD (OR = 1.72, 95%CI = 1.10-2.67, p = 0.02) was observed. Conclusions: This study comprehends only five existing case-control studies and the result is negative. The positive trend might appear when the sample size is enlarged. In the future, more large-scale casecontrol or cohort studies should be done to enhance the association between ALDH2 polymorphism and AD or other neurodegenerative diseases.

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