scholarly journals Innovative Conservation of Inhaled Medication Devices During the COVID-19 Pandemic Through a Canister Reassignment Process

2020 ◽  
Vol 1 (0) ◽  
Author(s):  
Mandelin K. Cooper ◽  
L. Hayley Burgess ◽  
Karla Miller ◽  
Theresa Baltz ◽  
Julia Moody ◽  
...  
Keyword(s):  
Inhaled Medication

Prescription and use of inhaled medication in patients with asthma and COPD: Baseline-data of an adherence-Intervention-study

2017 ◽  
Author(s):  
Claudia Gregoriano ◽  
Thomas Dieterle ◽  
Anna-Lisa Flamm ◽  
Selina D�rr ◽  
Amanda Baum ◽  
...  
Keyword(s):  
Intervention Study ◽  
Baseline Data ◽  
Adherence Intervention ◽  
Inhaled Medication

scholarly journals Inhalers and nebulizers: basic principles and preliminary measurements

2018 ◽  
Vol 180 ◽  
pp. 02068
Author(s):  
Ondrej Misik ◽  
Frantisek Lizal ◽  
Vahid Farhikhteh Asl ◽  
Miloslav Belka ◽  
Jan Jedelsky ◽  
...  
Keyword(s):  
Hospital Care ◽  
Aerosol Particles ◽  
Experimental Setup ◽  
Size Distributions ◽  
Particle Size Distributions ◽  
Basic Principles ◽  
Physical Mechanisms ◽  
Inhaled Particles ◽  
Human Airways ◽  
Inhaled Medication

Inhalers are hand-held devices which are used for administration of therapeutic aerosols via inhalation. Nebulizers are larger devices serving for home and hospital care using inhaled medication. This contribution describes the basic principles of dispersion of aerosol particles used in various types of inhalers and nebulizers, and lists the basic physical mechanisms contributing to the deposition of inhaled particles in the human airways. The second part of this article presents experimental setup, methodology and preliminary results of particle size distributions produced by several selected inhalers and nebulizers.

scholarly journals Inhaled medication for asthma management: evaluation of how asthma patients, medical students, and doctors use the different devices

2003 ◽  
Vol 29 (2) ◽  
pp. 75-81 ◽  
Author(s):  
Janaína Barbosa Muniz ◽  
Carlos Roberto Padovani ◽  
Irma Godoy
Keyword(s):  
Health Care ◽  
Medical Students ◽  
Health Care Professionals ◽  
Airflow Obstruction ◽  
Asthma Management ◽  
Outpatient Service ◽  
Inhalation Therapy ◽  
Metered Dose ◽  
Asthma Patients ◽  
Inhaled Medication

Asthma results from a combination of three essential features: airflow obstruction, hyperresponsiveness of airways to endogenous or exogenous stimuli and inflammation. Inadequacy of the techniques to use different inhalation devices is one of the causes of therapeutic failure. The main purpose of this study was to evaluate how 20 medical students, 36 resident physicians of Internal Medicine/Pediatrics, and 40 asthma patients used three devices for inhalation therapy containing placebo. All patients were followed at the Pulmonary Outpatient Service of Botucatu Medical School and had been using inhaled medication for at least six months. The following devices were evaluated: metered dose inhalers (MDI), dry powder inhalers (DPI), and MDI attached to a spacer device. A single observer applied a protocol containing the main steps necessary to obtain a good inhaler technique to follow and grade the use of different devices. Health care professionals tested all three devices and patients tested only the device being used on their management. MDI was the device best known by doctors and patients. MDI use was associated with errors related to the coordination between inspiration and device activation. Failure to exhale completely before inhalation of the powder was the most frequent error observed with DPI use. In summary, patients did not receive precise instruction on how to use inhaled medication and health care professionals were not well prepared to adequately teach their patients.

scholarly journals Understanding patient adherence to inhaled medication: The social representations of COPD

2017 ◽  
Vol 23 (6) ◽  
pp. 358-359
Author(s):  
A. Duarte-de-Araújo ◽  
P. Teixeira ◽  
M. Figueiredo ◽  
V. Hespanhol ◽  
J. Correia-de-Sousa
Keyword(s):  
Patient Adherence ◽  
Social Representations ◽  
The Social ◽  
Inhaled Medication

scholarly journals Patients with underuse or overuse of inhaled corticosteroids have different perceptions and beliefs regarding COPD and inhaled medication

2018 ◽  
Vol Volume 12 ◽  
pp. 1777-1783 ◽  
Author(s):  
Kirsten Koehorst-ter Huurne ◽  
Marjolein Brusse-Keizer ◽  
Paul van der Valk ◽  
Kris Movig ◽  
Job van der Palen ◽  
...  
Keyword(s):  
Inhaled Corticosteroids ◽  
Inhaled Medication

scholarly journals Inhaled medication therapy for bronchiectasis: status quo and the next frontier

2018 ◽  
Vol 27 (3) ◽  
pp. 211-218 ◽  
Author(s):  
Chun-lan Chen ◽  
Yan Huang ◽  
Yong-hua Gao ◽  
Rong-chang Chen ◽  
Nan-shan Zhong ◽  
...  
Keyword(s):  
Status Quo ◽  
Medication Therapy ◽  
Inhaled Medication

Virtual Assessment of the Performance of an Inhalation Drug Delivery Device

2007 ◽  
Author(s):  
Françoise Dufour ◽  
Gavin Davies
Keyword(s):  
Drug Delivery ◽  
Nasal Delivery ◽  
Pharmaceutical Aerosols ◽  
Drug Delivery Device ◽  
Non Invasive ◽  
Optimal Drug ◽  
Drug Dispersion ◽  
Computational Fluid Dynamics Cfd ◽  
Inhaler Devices ◽  
Inhaled Medication

Inhalation therapies are gaining popularity for both respiratory and non-respiratory therapies. However the challenge remains to achieve optimal drug delivery because of the complex interaction between inhaler devices, drug formulations along with patients’ coordination and physiology. In order to lower R&D costs and efforts, and understand better the mechanics of pharmaceutical aerosols, system designers are looking for comprehensive tools enabling them to reproduce virtual inhalation processes. Computational fluid dynamics (CFD) techniques represent a non-invasive way of predicting the fate of inhaled medication from oral or nasal delivery devices. The object of this work is to apply CFD methodology to model the full inhalation mechanism, from the drug dispersion inside the device and delivery to the patient, to its journey within the respiratory tract.

scholarly journals Does a tailored intervention to promote adherence in patients with chronic lung disease affect exacerbations? A randomized controlled trial

2019 ◽  
Vol 20 (1) ◽  
Author(s):  
Claudia Gregoriano ◽  
Thomas Dieterle ◽  
Anna-Lisa Breitenstein ◽  
Selina Dürr ◽  
Amanda Baum ◽  
...  
Keyword(s):  
Randomized Controlled Trial ◽  
Controlled Trial ◽  
Intervention Group ◽  
Ambulatory Setting ◽  
Randomized Controlled ◽  
Phone Calls ◽  
Copd Patients ◽  
The Impact ◽  
Inhaled Medication

Abstract Background Poor medication-adherence is common in chronic lung patients, resulting in reduced health-outcomes and increased healthcare-costs. This study aimed to investigate the impact of an acoustic reminder and support calls on adherence to inhaled therapy in asthma and COPD patients and to determine their effect on exacerbations. Methods This single-blinded randomized controlled trial investigated asthma and COPD patients during 6 months in an ambulatory setting. The intervention consisted of daily alarm clock and support phone calls, whenever use of rescue medication doubled or inhaled medication was not taken as prescribed. Primary outcome was time to next exacerbation. Frequency of exacerbations, adherence to inhaled medication and quality of life scores were secondary outcomes. Cox and Poisson regression were used to determine intervention effect on time to exacerbation and frequency of exacerbations, respectively. Results Seventy-five participants were assigned to the intervention group and 74 to usual follow-up care. During a median follow-up of 6.2 months, 22 and 28% in the intervention and control groups respectively, experienced at least one exacerbation. Intervention had no effect on time to first exacerbation (HR 0.65, 95% CI 0.21 to 2.07, P = .24), but showed a trend toward a 39% decreased frequency of exacerbations (RR = 0.61, 95% CI 0.35 to 1.03, P = .070) for the adjusted models, respectively. The intervention group had significantly more days with 80–100% taking adherence regarding puff inhalers (82 ± 14% vs. 60 ± 30%, P < .001) and dry powder capsules (90 ± .10% vs. 80 ± 21%, P = .01). Timing adherence in participants using puff inhalers was higher in the intervention group (69 ± 25% vs. 51 ± 33%, P < .001). No significant differences in QoL were found between the two groups. Conclusion Participants assigned to the intervention group had significantly better taking and timing adherence of inhaled medication resulting in a trend towards a decreased frequency of exacerbations. However, no effect on time to next exacerbation was observed. Trial registration ClinicalTrials.gov: NCT02386722, Registered 14 February 2014.

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