scholarly journals Surgical Outcome & Cost Analysis of Single Stage Anterior Decompression and Cage Fixation in Patients with Thoracic and Lumbar Tuberculous Spondylitis: A Single Centre Experience Over Six – Years with Comprehensive Literature Review

2020 ◽  
Vol 24 (2) ◽  
pp. 156-163
Author(s):  
FAIQA FILZA KHAN ◽  
MUHAMMAD MUKHTAR KHAN ◽  
ZAHOOR AHMED ◽  
TARIQ KHAN
Keyword(s):  
Pulmonary Complications ◽  
Single Stage ◽  
Class Iii ◽  
Anterior Decompression ◽  
Tuberculous Spondylitis ◽  
Single Centre Experience ◽  
Cage Subsidence ◽  
Graft Extrusion ◽  
Grade 3 ◽  
Paraspinal Abscess

Objective:  For Tuberculous spondylitis (TS) the optimal mode of management for extensive tuberculous spondylitis is still a subject of debate. We determined the outcome for single stage anterior decompression and cage fixation for dorso-lumbar TS. Material and Methods:  This prospective study was conducted between 2012 and 2018. Worsening or new onset neurological deficit, increasing deformity, large paraspinal abscess and those not responding to anti-tuberculous drug therapy were included. Patients with severe comorbidities (> ASA class III) and recurrent cases were excluded. Demographics, clinical features, radiological characteristics, intraoperative details, postoperative complications and follow-up condition were recorded. Results:  One patient with mean age of 45.6 ± 14.9 years with 17 (54.8%) males and 14 (45.2%) females. Mean symptoms duration was 71.9 ± 29.4 days. 41.9% had spasticity & 25.8% had sphincter dysfunction on presentation. Half (48%) of patients had a Frankel grade 3 or less bilaterally. Mean length of the procedure was 137.4 ± 19.9 minutes. 19.4% (n = 6) had postoperative pulmonary complications, 16.1% (n = 5) wound infection, 9.7% (n = 3) had worsening of neurologic deficit and one (3.2%) remained static. Graft extrusion and cage subsidence were noted in one (3.2%) patient each. Favorable outcome was observed in 83.9% (n = 26) while 16.1% (n = 5) had unfavorable outcome. Mean out-of-pocket cost was 164677.4 ± 11469.9 rupees (USD: 1187 approx). Conclusion:  Timely spinal decompression with stabilization at the onset of the Pott’s disease in patients who fulfil the criteria as surgical candidates carries a promising outcome.

Single-stage debridement, decompression, and circumferential reconstruction for lumbar tuberculous spondylitis: A posterior-only approach

2019 ◽  
Vol 9 (3) ◽  
pp. 89
Author(s):  
AdetunjiM Toluse ◽  
TaofeekO Adeyemi ◽  
AdeniyiS Ogunsakin ◽  
Asi-OquaE Bassey
Keyword(s):  
Single Stage ◽  
Tuberculous Spondylitis

scholarly journals Anterior Decompression by Sternum Splitting Approach for Kyphosis of Upper Thoracic Spine Caused by Tuberculous Spondylitis: A Case Report

2004 ◽  
Vol 53 (2) ◽  
pp. 281-283
Author(s):  
Kazushi Nakamura ◽  
Kazunori Yone ◽  
Kyoji Hayashi ◽  
Toshihiko Izumi ◽  
Shunji Matsunaga ◽  
...  
Keyword(s):  
Case Report ◽  
Thoracic Spine ◽  
Anterior Decompression ◽  
Tuberculous Spondylitis ◽  
Upper Thoracic Spine ◽  
Upper Thoracic

scholarly journals Hypospadias Repair: A Single Centre Experience

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
Mansoor Khan ◽  
Abdul Majeed ◽  
Waqas Hayat ◽  
Hidayat Ullah ◽  
Shazia Naz ◽  
...  
Keyword(s):  
Social Sciences ◽  
Postoperative Complications ◽  
Single Stage ◽  
Hypospadias Repair ◽  
Surgical Skill ◽  
Two Stage ◽  
Urethral Plate ◽  
Single Centre Experience ◽  
Male Patients ◽  
Hypospadias Surgery

Objectives. To determine the demographics and analyze the management and factors influencing the postoperative complications of hypospadias repair. Settings. Hayatabad Medical Complex Peshawar, Pakistan, from January 2007 to December 2011. Material and Methods. All male patients presenting with hypospadias irrespective of their ages were included in the study. The data were acquired from the hospital’s database and analyzed with Statistical Package for Social Sciences (SPSS). Results. A total of 428 patients with mean age of 8.12 ± 5.04 SD presented for hypospadias repair. Midpenile hypospadias were the most common. Chordee, meatal abnormalities, cryptorchidism, and inguinal hernias were observed in 74.3%, 9.6%, 2.8%, and 2.1% cases, respectively. Two-stage (Bracka) and TIP (tubularized incised urethral plate) repairs were performed in 76.2% and 20.8% of cases, respectively. The most common complications were edema and urethrocutaneous fistula (UCF). The complications were significantly lower in the hands of specialists than residents (P-value = 0.0086). The two-stage hypospadias repair resulted in higher complications frequency than single-stage repair (P value = 0.0001). Conclusion. Hypospadias surgery has a long learning curve because it requires a great deal of temperament, surgical skill and acquaintance with magnifications. Single-stage repair should be encouraged wherever applicable due to its lower postoperative complications.

A phase II study of cetuximab (C225) in combination with chemoradiation (CRT) in patients (pts) with stage III A/B non-small cell lung cancer (NSCLC): An interim report of the RTOG 0324 trial

2007 ◽  
Vol 25 (18_suppl) ◽  
pp. 7531-7531 ◽  
Author(s):  
G. Blumenschein ◽  
J. Moughan ◽  
W. Curran ◽  
F. Robert ◽  
F. Fossella ◽  
...  
Keyword(s):  
Phase Ii ◽  
Performance Status ◽  
Growth Factor Receptor ◽  
Pulmonary Complications ◽  
Model Systems ◽  
Stage Iii ◽  
Preclinical Model ◽  
Eligibility Criteria ◽  
Trial Testing ◽  
Grade 3

7531 Background: Cetuximab (C225) is a chimerized monoclonal antibody that targets the epidermal growth factor receptor (EGFR). NSCLC commonly expresses the EGFR, which is associated with aggressive tumor behavior and poor clinical outcome. Preclinical model systems demonstrate radiosensitization following molecular inhibition of EGFR signaling. Methods: We report a phase II trial testing the combination of C225 with CRT in unresectable stage III NSCLC with a planned sample size of 84 PTS. Eligibility criteria included Zubrod performance status (PS) = 1, weight loss = 5% over past 3 months, FEV1 = 1.2 l, adequate hematologic, hepatic, and renal function. PTS received an initial dose of C225 (400 mg/m2) on day 1 of week 1, then weekly doses of C225 (250 mg/m2) until completion of therapy (weeks 2 –17). During week 2, patients started CRT (63 Gy/35 fractions) with weekly carboplatin (C) AUC 2 and paclitaxel (P) 45 mg/m2 × 6 doses followed by C (AUC 6) and P (200 mg/m2) × 2 cycles (weeks 12–17). Interim monitoring for severe (grade = 3) or excessive non-hematologic toxicities occurred after pts had been treated and followed for at least 90 days after RT. Primary endpoints include safety and compliance of concurrent C225 and CRT. Results: 93 pts were enrolled with 87 evaluable pts. Pts characteristics: 57% male, median age 64 years (range 42–85), 47% PS 0, 46% stage IIIA. Median follow-up is 14 months. Response rate is 62% (n=54) and 12 month overall survival (OS) is 68% (# at risk=56). Adverse events related to treatment include 20% (n=17) of pts with grade 4 hematologic toxicities and 7 pts who had grade 3 esophagitis. There was 1 infection related death, 1 death NOS, and 3 pts who died of pulmonary complications (adult respiratory distress syndrome, pneumonitis, and hypoxia). Conclusions: The combination of C225 with CRT is feasible. Further study will be needed to determine whether the addition C225 to CRT enhances toxicity or efficacy. Complete compliance and toxicity data along with 18 month OS will be reported. No significant financial relationships to disclose.

scholarly journals Application of Jigsaw Learning Method Using Play Money Learning Media to Improve Mathematics Learning Outcomes

2021 ◽  
Vol 3 (4) ◽  
pp. 208
Author(s):  
Rina Eka Fitriani
Keyword(s):  
Learning Outcomes ◽  
Quantitative Data ◽  
Qualitative Data ◽  
Mathematics Learning ◽  
Class Iii ◽  
Research Subjects ◽  
Minimum Score ◽  
Jigsaw Method ◽  
Grade 3 ◽  
Academic Year

<p><em>This study</em><em> aims to improve mathematics learning outcomes about money in class III semester I SDN 4 Mangin, Karangrayung District, Grobogan Regency, 2017/2018 academic year through toy money media and the application of Jigsaw learning m</em><em>ethod</em><em>. The research subjects were grade 3 students at SDN 4 Mangin, totaling 14 students. The research design is classroom action research consisting of two cycles. Each cycle consists of 2 meetings. Data collection techniques using evaluation in the form of assignments, worksheets and evaluation questions. While the data analysis includes qualitative data and quantitative data. Learning outcomes from the pre-cycle were obtained, from 14 students, only 5 students (36%) had reached the mastery target with a minimum score of 65. In the first cycle, classical completeness was 71%. While in the second cycle of 100%. These results indicate that the application of the Jigsaw method using toy money media can improve mathematics learning outcomes for grade 3 students at SDN 4 Mangin.</em></p>

scholarly journals Development of Pop Up Book Media Material Distinguishing Characteristics of Healthy and Unfit Environments Class III Students Elementary School

2018 ◽  
Vol 2 (1) ◽  
Author(s):  
Erwin Putera Permana ◽  
Yeny Endah Purnama Sari
Keyword(s):  
Natural Science ◽  
Teaching Method ◽  
Learning Material ◽  
Class Iii ◽  
School Students ◽  
Implementation Evaluation ◽  
Conventional Teaching ◽  
Environment Characteristic ◽  
The Media ◽  
Grade 3

This research is based on the observation in the third grade of Natural Science (IPA) subject matter of healthy and unhealthy environment characteristic, that most of students have difficulty in learning because the teacher uses conventional teaching method. In addition, the use of learning media is considered less maximized by teachers. This research is research and development (R & D) with model of ADDIE development. Stages there are 5 stages namely 1) Analysis (Analysis), Development (Design), Implementation (Implementation), Evaluation (Evaluation). Validation is done by material experts, media experts, and classroom teachers. The conclusion of this research is (1) Result of Development of Pop Up Book media with material to distinguish the characteristics of healthy and unhealthy environment Valid. (2) The teacher's response to the learning media of Pop Up Book that was developed, after being used in learning material, characteristic of healthy and unhealthy environment obtained good response. Likewise the response of students to this media get a positive response. (3) Pop Up Book media characteristics of a healthy and unhealthy environment based on the overall assessment of the percentage of assessment is in the category of very appropriate to be used as a medium of learning Natural Science for grade 3 primary school students. Based on the conclusions of this study, recommended: (1) for teachers, one of the media that can be used in supporting the learning process is Pop Up Book, can help students become more active and can create a fun class atmosphere. (2) For further research, trials should be conducted more widely, so as to produce a widely used learning medium.

scholarly journals Management of pancreatic trauma in adult patients: a single centre experience

2020 ◽  
Vol 7 (3) ◽  
pp. 705
Author(s):  
Balakrishna N. Shetty ◽  
Sathish Obalanarasimhaiah ◽  
Nagesh Nayankarahalli Swamigowda ◽  
Mannem Manoj Kumar ◽  
Jyotirmay Jena
Keyword(s):  
Traffic Accident ◽  
American Association ◽  
Road Traffic ◽  
Demographic Data ◽  
Pancreatic Injury ◽  
Pancreatic Trauma ◽  
Single Centre Experience ◽  
Grade Ii ◽  
Baseline Characteristics ◽  
Grade 3

Background: Pancreatic trauma is very rare and its management is complex. The aim of this study was to report our experience in the management of pancreatic trauma.Methods: All patients who were admitted with pancreatic trauma from May 2017 to May 2019 were reviewed retrospectively. Demographic data and baseline characteristics were recorded. Grading of pancreatic trauma was carried out according to the American Association for surgery for Trauma (AAST). Data were represented by frequency and mean.Results: A total of 24 patients were admitted with pancreatic trauma in the study period. Road traffic accident (n=17) was the leading cause followed by falls (n=5) and assault (n=2). Out of 24 patients, 3 patients had grade I pancreatic injury, 6 patients had grade II AAST injury, 9 patients had grade III injury and 6 patients had grade IV injury. No patients had grade V injury. Mean hospital stay was 12.3±4.2 days. One patient with grade 2 injury underwent surgery for liver laceration, all others were managed conservatively. Patients with grade 3 and 4 injuries were managed conservatively. One patient with grade 3 injury required, cystogastrostomy for pseudocyst 1 month after the index admission. Two patients of grade 4 injury underwent surgery, one patient for traumatic pseudocyst after 1 month and another patient for bleeding pseudoaneurysm of gastroduodenal artery 1 month after trauma. No patient underwent pancreatectomy. There was no mortality in the study population.Conclusions: Pancreatic trauma can be managed conservatively irrespective of the grade of injury in haemodynamically stable patients. 

Sign in / Sign up

Export Citation Format

Share Document