Intra-Arterial Chemotherapy for Pancreatic Cancer

The review presents an analysis of the literature and our own data on the use of intra-arterial chemotherapy in pancreatic cancer. It is concluded that transcatheter arterial administration of cytostatics is a relatively safe and effective method of treatment. Combination of celiac axis infusion with arterial chemoembolization, as well as infusion with radiotherapy increase the survival. Neoand adjuvant arterial chemotherapy improves the results of pancreatic surgery. The use of new locoregional chemotherapy regimens is promising and requires further study.

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Intention to treat outcomes among patients with pancreatic cancer treated using International Study Group on Pancreatic Surgery recommended pathways for resectable and borderline resectable disease

ANZ Journal of Surgery ◽

10.1111/ans.16643 ◽

2021 ◽

Author(s):

Sivesh K. Kamarajah ◽

Nikolaos Chatzizacharias ◽

James Hodson ◽

Francesca Marcon ◽

Marit Kalisvaart ◽

...

Keyword(s):

Pancreatic Cancer ◽

Pancreatic Surgery ◽

International Study ◽

Study Group ◽

Borderline Resectable ◽

Resectable Disease ◽

Intention To Treat ◽

International Study Group

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Effects of COVID-19 Pandemic on the Treatment of Pancreatic Cancer: A Perspective from Central Europe

Digestive Surgery ◽

10.1159/000513157 ◽

2021 ◽

Vol 38 (2) ◽

pp. 158-165

Author(s):

Ilaria Pergolini ◽

I. Ekin Demir ◽

Christian Stöss ◽

Klaus Emmanuel ◽

Robert Rosenberg ◽

...

Keyword(s):

Pancreatic Cancer ◽

Cancer Patients ◽

Central Europe ◽

Pancreatic Surgery ◽

Online Survey ◽

Viral Infections ◽

High Volume ◽

Tumor Board ◽

Standards Of Care ◽

The Impact

Background: This survey aimed to register changes determined by the COVID-19 pandemic on pancreatic surgery in a specific geographic area (Germany, Austria, and Switzerland) to evaluate the impact of the pandemic and obtain interesting cues for the future. Methods: An online survey was designed using Google Forms focusing on the local impact of the pandemic on pancreatic surgery. The survey was conducted at 2 different time points, during and after the lockdown. Results: Twenty-five respondents (25/56) completed the survey. Many aspects of oncological care have been affected with restrictions and delays: staging, tumor board, treatment selection, postoperative course, adjuvant treatments, outpatient care, and follow-up. Overall, 60% of respondents have prioritized pancreatic cancer patients according to stage, age, and comorbidities, and 40% opted not to operate high-risk patients. However, for 96% of participants, the standards of care were guaranteed. Discussion/Conclusions: The first wave of the COVID-19 pandemic had an important impact on pancreatic cancer surgery in central Europe. Guidelines for prompt interventions and prevention of the spread of viral infections in the surgical environment are needed to avoid a deterioration of care in cancer patients in the event of a second wave or a new pandemic. High-volume centers for pancreatic surgery should be preferred and their activity maintained. Virtual conferences have proven to be efficient during this pandemic and should be implemented in the near future.

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