scholarly journals Trend in the use of topical ocular anti-infectives in a region of Spain between 2015 and 2019: a population-based registry study

2020 ◽  
Vol 33 (6) ◽  
pp. 453-458
Author(s):  
Eduardo Gutiérrez-Abejón ◽  
Francisco Herrera-Gómez ◽  
Ignacio J. Ayestarán-Martínez ◽  
Francisco Javier Álvarez ◽  
Keyword(s):  
Population Distribution ◽  
The Elderly ◽  
Population Based ◽  
European Population ◽  
Registry Study ◽  
Total Consumption ◽  
Age And Gender ◽  
Ocular Drugs ◽  
And Gender ◽  
Population Based Registry

Objectives. This study presents the use and trends of use of topical ocular anti-infectives into a European population in the current decade (2015 to 2019) with an analysis of concomitant use with other ocular drugs, considering distribution by age and gender. Patients and Methods. A population-based registry study was carried out to assess the ocular anti-infectives use from 2015 to 2019. All dispensations of these medicines at pharmacies in the largest region of Spain, Castile and León, was accessed. The number of packages dispensed, the percentage of the population under treatment, diagnosis, and the concomitant use with other ocular medicines was observed. For all analyses, the population distribution by age and gender was considered. Results. An average of 198,000 packages of topical ocular anti-infectives were dispensed annually to 5.38% of the population, and more commonly for women than for men (5.83% vs. 4.91%). Children and the elderly used more these medicines. Tobramycin, alone or in combination, accounted for more than 68% of the total consumption (135,000 packages per year), and was the most widely used anti-infective in almost all identified diagnoses. Conjunctivitis (50.12%), and stye (11.51%) were the most frequent diagnoses. The consumption of ocular anti-infectives increased by 8.23% from 2015 to 2019, and more among men than in women. Conclusions. Our findings show that the most used topical ocular anti-infective was tobramycin, in accordance with the clinical practice guidelines recommendations. However, ocular infections are sometimes treated empirically, especially conjunctivitis.

scholarly journals Use of driving-impairing medicines by a Spanish population: a population-based registry study

BMJ Open ◽  
2017 ◽  
Vol 7 (11) ◽  
pp. e017618 ◽  
Author(s):  
Eduardo Gutierrez-Abejón ◽  
Francisco Herrera-Gómez ◽  
Paloma Criado-Espegel ◽  
F Javier Alvarez
Keyword(s):  
General Population ◽  
Census Data ◽  
Population Based ◽  
Spanish Population ◽  
Registry Study ◽  
Age And Gender ◽  
Patterns Of Use ◽  
And Gender ◽  
Population Based Registry ◽  
Chronic Use

ObjectiveTo assess the use of driving-impairing medicines (DIM) in the general population with special reference to length of use and concomitant use.DesignPopulation-based registry study.SettingThe year 2015 granted medicines consumption data recorded in the Castile and León (Spain) medicine dispensation registry was consulted.ParticipantsMedicines and DIM consumers from a Spanish population (Castile and León: 2.4 million inhabitants).ExposureMedicines and DIM consumption. Patterns of use by age and gender based on the length of use (acute: 1–7 days, subacute: 8–29 days and chronic use: ≥30 days) were of interest. Estimations regarding the distribution of licensed drivers by age and gender were employed to determine the patterns of use of DIM.ResultsDIM were consumed by 34.4% (95% CI 34.3% to 34.5%) of the general population in 2015, more commonly with regularity (chronic use: 22.5% vs acute use: 5.3%) and more frequently by the elderly. On average, 2.3 DIM per person were dispensed, particularly to chronic users (2.8 DIM per person). Age and gender distribution differences were observed between the Castile and León medicine dispensation registry data and the drivers’ license census data. Of all DIM dispensed, 83.8% were in the Anatomical Therapeutic Chemical code group nervous system medicines (N), which were prescribed to 29.2% of the population.ConclusionsThe use of DIM was frequent in the general population. Chronic use was common, but acute and subacute use should also be considered. This finding highlights the need to make patients, health professionals, health providers, medicine regulatory agencies and policy-makers at large aware of the role DIM play in traffic safety.

scholarly journals Trends in Antidepressants Use in Spain between 2015 and 2018: Analyses from a Population-Based Registry Study with Reference to Driving

2020 ◽  
Vol 13 (4) ◽  
pp. 61 ◽  
Author(s):  
Eduardo Gutiérrez-Abejón ◽  
Francisco Herrera-Gómez ◽  
Paloma Criado-Espegel ◽  
F. Javier Álvarez
Keyword(s):  
Traffic Accidents ◽  
Population Distribution ◽  
Population Based ◽  
Driving Under The Influence ◽  
Registry Study ◽  
Starting Point ◽  
And Gender ◽  
Population Based Registry ◽  
Classification Category ◽  
Chronic Use

Antidepressants are considered driving-impairing medicines (DIM). This is a population-based registry study that shows the trend in the use of antidepressants in Castile and León, Spain, from 2015 to 2018. Data on antidepressant dispensations at pharmacies and the adjusted use of these medicines by the driver population are presented. For the purposes of analysis, population distribution by age and gender has been taken into account, as well as the three Driving Under the Influence of Drugs, alcohol, and medicines (DRUID) categories. Antidepressants were used by 8.56% of the general population and 5.66% of drivers. Antidepressants were used more commonly by females than by males (12.12% vs. 4.87%, χ² = 1325.124, p = 0.001), and users increased as the age increased, even if women who drive used less antidepressants after turning 60 years of age. Chronic use of antidepressants was relevant (8.28%) in the same way as daily use (3.15%). Most of the consumption included SSRIs (4.99%), which are also known as “other antidepressants” (3.71%). Regardless of antidepressants consumed, users took 2.75 ± 1.19 DIMs, which are mainly anxiolytics (58.80%) and opioids (26.43%). Lastly, regarding consumption of antidepressants according to the DRUID classification, category I predominated over categories II and III. Our findings should serve as a starting point for health and traffic authorities to raise awareness of the risk for traffic accidents, especially involving SSRIs.

scholarly journals The Trends in Opioid Use in Castile and Leon, Spain: A Population-Based Registry Analysis of Dispensations in 2015 to 2018

2019 ◽  
Vol 8 (12) ◽  
pp. 2148 ◽  
Author(s):  
Francisco Herrera-Gómez ◽  
Eduardo Gutierrez-Abejón ◽  
Ignacio Ayestarán ◽  
Paloma Criado-Espegel ◽  
F. Javier Álvarez
Keyword(s):  
Opioid Analgesics ◽  
The Elderly ◽  
Population Based ◽  
Common Finding ◽  
Opioid Use ◽  
Safe Driving ◽  
Frequent Use ◽  
And Gender ◽  
Multiple Drugs ◽  
Population Based Registry

Opioids are driving-impairing medicines (DIM). To assess the evolution and trends of opioid analgesics use between 2015 and 2018 in Castile and Leon (Spain), a population-based registry study was conceived. The length of opioid use and its concomitant use with other DIMs were studied. Analyses were done considering age and gender distributions. Adjusted consumption for licensed drivers is also presented. Of the 5 million dispensations recorded between 2015 and 2018, opioid analgesics were dispensed to 11.44% of the general population and 8.72% of vehicle drivers. Increases among daily users (2.6 times higher) and chronic users (1.5% higher) were noted, supporting the overall increase in opioid use (1.5%). The use of multiple drugs including other DIMs was a common finding (mean ± SD, 2.54 ± 0.01). Acute use (5.26%) and chronic use (3.20%) were also frequent. Formulations combining opioid analgesics with nonopioid analgesics were preferred. The use of opioids increased in Spain between 2015 and 2018. Concomitant use with other DIMS especially affects women and the elderly. Frequent use of opioid analgesics with other DIMs is a serious problem for drivers and increases the risk of accidents. Promoting safe driving should be a main objective of health authorities, to be achieved by developing and implementing educational activities for healthcare professionals and patients.

scholarly journals P01.078 Glioma surgery in the elderly, a retrospective population based registry study

2018 ◽  
Vol 20 (suppl_3) ◽  
pp. iii247-iii248
Author(s):  
D Löfgren ◽  
M Olivecrona
Keyword(s):  
The Elderly ◽  
Population Based ◽  
Registry Study ◽  
Glioma Surgery ◽  
Surgery In The Elderly ◽  
Population Based Registry

scholarly journals P05.54 Meningioma surgery in the elderly, a retrospective population based registry study

2018 ◽  
Vol 20 (suppl_3) ◽  
pp. iii315-iii315
Author(s):  
D Löfgren ◽  
M Olivecrona
Keyword(s):  
The Elderly ◽  
Population Based ◽  
Registry Study ◽  
Surgery In The Elderly ◽  
Meningioma Surgery ◽  
Population Based Registry

scholarly journals Case fatality, mortality, socio‐demographic, and screening of COVID‐19 in the elderly population: A population‐based registry study in Iran

2022 ◽  
Author(s):  
Elham Davtalab Esmaeili ◽  
Ali Fakhari ◽  
Behrouz Naghili ◽  
Farzad Khodamoradi ◽  
Hosein Azizi
Keyword(s):  
Elderly Population ◽  
Case Fatality ◽  
The Elderly ◽  
Population Based ◽  
Registry Study ◽  
Population Based Registry

Neonatal and maternal outcome after blastocyst transfer: a population-based registry study

2016 ◽  
Vol 214 (3) ◽  
pp. 378.e1-378.e10 ◽  
Author(s):  
Erica Ginström Ernstad ◽  
Christina Bergh ◽  
Ali Khatibi ◽  
Karin B.M. Källén ◽  
Göran Westlander ◽  
...  
Keyword(s):  
Population Based ◽  
Maternal Outcome ◽  
Blastocyst Transfer ◽  
Registry Study ◽  
Population Based Registry

scholarly journals Influence of Gender on Cardiac and Encephalic Inflammation in the Elderly with Cysticercosis: A Case Control Study

2012 ◽  
Vol 2012 ◽  
pp. 1-6
Author(s):  
Camila Lourencini Cavellani ◽  
Rosana Rosa Miranda Corrêa ◽  
Mara Lúcia Fonseca Ferraz ◽  
Laura Penna Rocha ◽  
Ana Carolina Guimarães Faleiros ◽  
...  
Keyword(s):  
Inflammatory Infiltrate ◽  
Case Control Study ◽  
The Elderly ◽  
Brain Parenchyma ◽  
Elderly Group ◽  
University Hospital ◽  
Evolutionary Stage ◽  
Age And Gender ◽  
And Gender ◽  
Control Study

Background. The present study explores the influence of the host’s age and gender upon the inflammatory infiltrate. We aimed to quantify the inflammatory infiltrate caused by cysticercosis, which is related to aging, in the heart and in the encephalon.Methods. 75 autopsy protocols with cysticercosis diagnosis from department of pathology at a university hospital from 1970 to 2008 were reviewed. Two groups were formed: elderly with cysticercosis and nonelderly with cysticercosis. We used KS-300 (Kontron-Zeiss) software for morphometric analysis of the inflammation.Results.The elderly had an average of3.1±2.5cysticerci, whereas the non-elderly had2.7±3.8parasites. The non-elderly group with cysticercosis had significantly more inflammation, both cardiac and encephalic, than the elderly group. The elderly females with cysticercosis had more cardiac and encephalic inflammation.Conclusions. In this study, we showed that the non-elderly had significantly more cardiac and encephalic inflammation than the elderly, and that such inflammatory infiltrate decreases with age and depends upon the evolutionary stage of the cysticercus. Furthermore, there are differences concerning gender in the intensity of the inflammatory response due to cysticerci in the heart and brain parenchyma during senescence. Even during this period, women continue to have a more intense response to the parasitosis.

Sign in / Sign up

Export Citation Format

Share Document