Phytochemicals of Gentianaceae: A Review of Pharmacological Properties

1970 ◽  
Vol 1 (1) ◽  
pp. 33-36 ◽  
Author(s):  
Amritpal Singh
Keyword(s):  
Pharmacological Activity ◽  
Review Paper ◽  
Therapeutic Agents ◽  
Pharmacological Properties ◽  
Topoisomerase Inhibition ◽  
The Family ◽  
Secoiridoid Glycosides ◽  
Anti Inflammatory

Aim of the review paper is to give an enlightenment on potential phyto-constituents of Gentianaceae.  Bitter principles (secoiridoid glycosides) and xanthones are widely distributed among plants belonging to the family Gentianaceae. Phytochemicals like amarogentin, bellidifolin, gentianine and swerchirin have been reported to possess significant anti-inflammatory, analgesic, anti-asthmatic, anticonvulsant, antihistaminic, antimalarial, antiamoebic, cytoprotective, diuretic, hepatoprotective and hypoglycemic properties. Topoisomerase inhibition is significant pharmacological activity reported from amarogentin. Further investigations exploring possible use of these phytochemicals as therapeutic agents are warranted. The articles reviews certain pharmacological investigations carried out on phytochemicals reported from Gentianaceae

scholarly journals Erythrina suberosa: Ethnopharmacology, Phytochemistry and Biological Activities

Medicines ◽  
2019 ◽  
Vol 6 (4) ◽  
pp. 105 ◽  
Author(s):  
Felicia Patti ◽  
Yasaman Taheri ◽  
Javad Sharifi-Rad ◽  
Miquel Martorell ◽  
William C. Cho ◽  
...  
Keyword(s):  
Southeast Asia ◽  
Pharmacological Activity ◽  
Biological Activities ◽  
Deciduous Tree ◽  
Pharmacological Properties ◽  
Bioactive Components ◽  
Food Energy ◽  
Ornamental Tree ◽  
The Family ◽  
Coral Tree

Plants are a great and irreplaceable source of medicines, fuel, food, energy and even cosmetics. Since prehistory, humans have learned to use plants for survival, growth and proliferation and still today it relies on natural and cultivated vegetables for food and the source of novel compounds with pharmacological activity. Not only herbs and flowers, but also trees are used. Indeed, Erythrina suberosa Roxb. is a deciduous tree of the family Fabaceae, common in Southeast Asia. In India, E. suberosa is called the “corky coral tree” or simply the “Indian coral tree”, given its peculiar red-orange flowers that can flower throughout the year and its corky irregular bark covered by prickles. It is a plant commonly used as an ornamental tree, but it also holds ethnopharmacological and socioeconomic uses. This article explored phytobiological features of E. suberosa, analysing its taxonomy, examining its traditional and common uses and investigating its bioactive components and pharmacological properties.

scholarly journals Formulation and Evaluation of Nagarmotha Hair Oil

2021 ◽  
Vol 9 (12) ◽  
pp. 1107-1113
Author(s):  
Miss. Patil Shivani Navnath
Keyword(s):  
Chemical Composition ◽  
Essential Oil ◽  
Pharmacological Activity ◽  
Cyperus Rotundus ◽  
Chemical Components ◽  
Therapeutic Action ◽  
Extensive Review ◽  
The Family ◽  
Anti Inflammatory ◽  
Major Chemical

Abstract: The Presenace study investigation oil isolation form cyperus rotundus and the chemical composition of essential oil of root's of Cyprus rotundus.In india it's commonly known as nagarmotha.and it belongs to the family cyperacea.the major chemical components of this herb are essential oils.flavonoids, terpenoids, sesauiterpenes, cyproten, cyperene, aselinene, rotundene, valencene, cyperol, gurjunene, transcalamenenene, cad'Alene, cyperoutundone, mustskone, isocyperol, acyperone etc. Reserch studies have shown that it possesses various Pharmacological activity Such as diuretic,carmenative emmenagogue, anthelmintic, analgesic, anti-inflammatory, anti-dysentery, anti-rheumatic activities.an extensive review of the ancient traditional literature and madern research revealead that the drug has numerous therapeutic action. Several of which have been established scientifically, which may help the reserchers to set their minds for approaching the utility efficiency and potency of nagarmotha. Keywords: cyperus rotundus, cyprotene flavanoids nagarmotha.

Alchornea floribunda (Müll. Arg.), Phytochemistry and Biological Activities: A Review

2018 ◽  
Author(s):  
Matthias Onyebuchi Agbo ◽  
Festus Basden Chiedu Okoye ◽  
Godwin Chukwu Ebi ◽  
Patience Ogoamaka Osadebe
Keyword(s):  
Antibacterial Activity ◽  
Pharmacological Activity ◽  
Biological Activities ◽  
Bioactive Constituents ◽  
Anti Cancer ◽  
The Family ◽  
Anti Inflammatory

Alchornea floribunda is a small evergreen plant that grows up to 32 feet tall. It belongs to the family of Euphorbiaceae and is found mainly in African forest undergrowth. In Nigeria it’s leaves, stems and roots are widely used in folkloric medicine in the management of many ailments and diseases. The pharmacological activity of A. floribunda depends mainly on the part used. The leaves have been documented to possess anti-inflammatory, antimicrobial, antioxidant and anti-cancer activities while the roots and stems have been reported to possess antibacterial activity. Thus, this review summarizes all the findings and information about the phytochemistry, biological activities and various isolated bioactive constituents from the leaves, roots and stems of Alchornea floribunda.

scholarly journals Review on Natural Coumarin Lead Compounds for Their Pharmacological Activity

2013 ◽  
Vol 2013 ◽  
pp. 1-14 ◽  
Author(s):  
K. N. Venugopala ◽  
V. Rashmi ◽  
B. Odhav
Keyword(s):  
Natural Product ◽  
Pharmacological Activity ◽  
Dietary Exposure ◽  
Herbal Remedies ◽  
Pharmacological Properties ◽  
Lead Compounds ◽  
Natural Coumarin ◽  
Low Toxicity ◽  
Anti Inflammatory

Coumarin (2H-1-benzopyran-2-one) is a plant-derived natural product known for its pharmacological properties such as anti-inflammatory, anticoagulant, antibacterial, antifungal, antiviral, anticancer, antihypertensive, antitubercular, anticonvulsant, antiadipogenic, antihyperglycemic, antioxidant, and neuroprotective properties. Dietary exposure to benzopyrones is significant as these compounds are found in vegetables, fruits, seeds, nuts, coffee, tea, and wine. In view of the established low toxicity, relative cheapness, presence in the diet, and occurrence in various herbal remedies of coumarins, it appears prudent to evaluate their properties and applications further.

Coumarin–chalcone hybrids: promising agents with diverse pharmacological properties

RSC Advances ◽  
2016 ◽  
Vol 6 (13) ◽  
pp. 10846-10860 ◽  
Author(s):  
Han Wei ◽  
Jinlan Ruan ◽  
Xiaojian Zhang
Keyword(s):  
Pharmacological Activity ◽  
Therapeutic Agents ◽  
Pharmacological Properties

Coumarin–chalcone hybrid is an interesting template for medicinal chemists to develop therapeutic agents with diverse pharmacological activity.

A wide range of pharmacological properties of melatonin

2021 ◽  
Vol 19 (1) ◽  
pp. 103-106
Author(s):  
Eduard B. Arushanian ◽  
Stanislav S. Naumov
Keyword(s):  
Pineal Gland ◽  
Pharmacological Activity ◽  
Experimental Work ◽  
Pharmacological Properties ◽  
Wide Range ◽  
Anti Inflammatory

The pineal gland hormone melatonin has various pharmacological activity. In experimental work, he revealed anti-anxiety, antidepressant, neuroprotective, anti-pain and anti-inflammatory properties.

scholarly journals Ethnobotanical uses, phytochemistry and biological activities of Clerodendrum paniculatum L. (Lamiaceae): A comprehensive review

2018 ◽  
Vol 8 (5-s) ◽  
pp. 28-34
Author(s):  
T.R. Prashith Kekuda ◽  
S.J. Sudharshan
Keyword(s):  
Biological Activities ◽  
Pharmacological Properties ◽  
Comprehensive Review ◽  
The Family ◽  
Anti Inflammatory ◽  
Ethnobotanical Uses

Clerodendrum L. is an important genus in the family Lamiaceae in terms of its medicinal values and pharmacological properties. The genus comprises of more than 500 species distributed worldwide. In this review, we present an updated information on ethnobotanical uses, phytochemistry and biological activities of Clerodendrum paniculatum L. (Lamiaceae). The plant is one the most spectacular Clerodendrum species and is grown commonly for ornamental purpose. The plant is reported to have ethnomedicinal importance as the plant is used as remedy for ailments and disorders such as wounds, typhoid, snakebite, jaundice, giddiness, malaria, anemia and hemorrhoids. Various phytochemicals such as rutin, quercetin, β-sitosterol, β-amyrin, lupeol, oleanolic aldehyde acetate, stigmasta-4,25-dien-3-one, and (3β)-stigmasta-4,22,25-trien-3-ol have been identified in C. paniculatum. The plant is shown to exhibit biological activities such as antimicrobial, antioxidant, anthelmintic, anti-inflammatory, antimutagenic, cytotoxic, hypolipidemic, insecticidal and anti-ageing activity. Keywords: Clerodendrum paniculatum L., Ethnobotanical, Traditional, Phytochemicals, Biological activities

Non-Steroidal Anti-inflammatory Drugs (NSAIDs): Synthesis of Ibuprofen, Naproxen and Nabumetone

2019 ◽  
pp. 19-27
Keyword(s):  
Review Paper ◽  
Inflammatory Drugs ◽  
Anti Inflammatory ◽  
Synthetic Approaches

This review paper covers the major synthetic approaches attempted towards the synthesis of some Non-Steroidal Anti-Inflammatory Drugs (Naproxen, Ibuprofen and Nabumetone)

Pharmacologically potentials of different substituted coumarin derivatives

2019 ◽  
Author(s):  
Chem Int
Keyword(s):  
Benzene Ring ◽  
Bioactive Compounds ◽  
Biological Activities ◽  
Pharmacological Properties ◽  
Coumarin Derivatives ◽  
Wide Range ◽  
Anti Oxidant ◽  
Anti Inflammatory ◽  
Coumarin Compounds

Coumarin and its derivatives are widely spread in nature. Coumarin goes to agroup as benzopyrones, which consists of a benzene ring connected to a pyronemoiety. Coumarins displayed a broad range of pharmacologically useful profile.Coumarins are considered as a promising group of bioactive compounds thatexhibited a wide range of biological activities like anti-microbial, anti-viral,antiparasitic, anti-helmintic, analgesic, anti-inflammatory, anti-diabetic, anticancer,anti-oxidant, anti-proliferative, anti-convulsant, and antihypertensiveactivities etc. The coumarin compounds have immense interest due to theirdiverse pharmacological properties. In particular, these biological activities makecoumarin compounds more attractive and testing as novel therapeuticcompounds.

Current Status in the Design and Development of Agonists and Antagonists of Adenosine A3 Receptor as Potential Therapeutic Agents

2019 ◽  
Vol 25 (25) ◽  
pp. 2772-2787 ◽  
Author(s):  
Raghu P. Mailavaram ◽  
Omar H.A. Al-Attraqchi ◽  
Supratik Kar ◽  
Shinjita Ghosh
Keyword(s):  
Drug Target ◽  
Therapeutic Agents ◽  
G Protein Coupled Receptors ◽  
Current Status ◽  
Renal Diseases ◽  
Adenosine A3 Receptor ◽  
Drug Candidates ◽  
Novel Drugs ◽  
The Family ◽  
G Protein Coupled

Adenosine receptors (ARs) belongs to the family of G-protein coupled receptors (GPCR) that are responsible for the modulation of a wide variety of physiological functions. The ARs are also implicated in many diseases such as cancer, arthritis, cardiovascular and renal diseases. The adenosine A3 receptor (A3AR) has emerged as a potential drug target for the progress of new and effective therapeutic agents for the treatment of various pathological conditions. This receptor’s involvement in many diseases and its validity as a target has been established by many studies. Both agonists and antagonists of A3AR have been extensively investigated in the last decade with the goal of developing novel drugs for treating diseases related to immune disorders, inflammation, cancer, and others. In this review, we shall focus on the medicinal chemistry of A3AR ligands, exploring the diverse chemical classes that have been projected as future leading drug candidates. Also, the recent advances in the therapeuetic applications of A3AR ligands are highlighted.

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