A Corollary of Nanoporous Carrier Drug Delivery System: An Updated Perspective

Author(s):  
Om M Bagade ◽  
Shashikant N Dhole ◽  
Praveen D Chaudhar

Nanosponges have come into sight as one of the most promising fields of science because of their perceived applications in controlled drug delivery. It has been increasingly investigated to achieve targeted and sustained release of drugs. Nanosponges are one of the novel drug delivery system, which is gaining popularity now days because of their perceived application in controlled and site-specific drug delivery. The fundamental appeal of the nanosponge technology arises from the difficulty experienced with conventional formulations in releasing active ingredients over an extended period of time, unpleasant odor, greasiness and skin irritation. They are tiny sponge-like spherical particles with a large porous surface and are believed to contribute towards reduced side effects, improved stability, increased elegance and enhanced formulation flexibility. The present investigation in the appraisal describes nanosponge technology embracing its method of preparation, characterization, in-vitro and in-vivo evaluation methods along with recent research and future potential.

2019 ◽  
Vol 72 (3) ◽  
pp. 396-408 ◽  
Author(s):  
Ana Laís Nascimento Vieira ◽  
Michelle Franz‐Montan ◽  
Luís Fernando Cabeça ◽  
Eneida de Paula

RSC Advances ◽  
2015 ◽  
Vol 5 (56) ◽  
pp. 44998-45014 ◽  
Author(s):  
Krishnamurthy Shanthi ◽  
Karuppaiya Vimala ◽  
Dhanaraj Gopi ◽  
Soundarapandian Kannan

Schematic illustration of the possible mechanism of pH based drug delivery system of DOX conjugated PEGylated PdNPs induced apoptosis in HeLa cells.


2016 ◽  
Vol 224 ◽  
pp. 351-358 ◽  
Author(s):  
Faiyaz Shakeel ◽  
Mohammad Raish ◽  
Md. Khalid Anwer ◽  
Ramadan Al-Shdefat

Sign in / Sign up

Export Citation Format

Share Document