Postmortem Diagnosis of Hypertonic Dehydration by Chemical Analysis of Vitreous Humor

2017 ◽  
Vol 68 (11) ◽  
pp. 2650-2653
Author(s):  
Simona Irina Damian ◽  
Paul Nedelea ◽  
Sofia David ◽  
Anton Knieling ◽  
Sorin Moldoveanu ◽  
...  
Keyword(s):  
Differential Diagnosis ◽  
Cause Of Death ◽  
Vitreous Humor ◽  
The Other ◽  
Post Mortem ◽  
Postmortem Diagnosis ◽  
Post Mortem Interval ◽  
Biochemical Analyses ◽  
Diagnosis Criteria ◽  
Survival Interval

The aim of forensic autopsy is to accurately reconstitute, as much as possible, the circumstances of death (the cause of death and the mechanism of death, the post-mortem interval, the related pathology and its role, the survival interval). Post-mortem biochemical analyses can help to various extents in establishing these issues. In order to elucidate the issue of post-mortem biochemical investigations, we conducted an analysis of forensic casuistry within a delimited territory, for a period of 3 years in order to identify the elements necessary for the diagnosis of hypertonic dehydration. By grouping the cases depending on the immediate cause of death, the diagnosis criteria for hypertonic dehydration showed the possibility of performing the differential diagnosis by biochemical analyses performed in vitreous humor (sodium, chlorine, urea, creatinine), the criteria being not met in any of the other groups.

Post-mortem biochemistry of vitreous humor and glucose metabolism: an update

2011 ◽  
Vol 49 (8) ◽  
Author(s):  
Camille Boulagnon ◽  
Roselyne Garnotel ◽  
Paul Fornes ◽  
Philippe Gillery
Keyword(s):  
Diabetes Mellitus ◽  
Clinical Practice ◽  
Glucose Metabolism ◽  
Cause Of Death ◽  
Diabetic Complications ◽  
Metabolic Pathways ◽  
Vitreous Humor ◽  
Time Since Death ◽  
Post Mortem ◽  
Biochemical Analyses

AbstractPost-mortem biochemistry, also called thanatochemistry, has proved useful in forensics for estimating the time since death and assessing the cause of death. Ketoacidosis is a frequent complication of diabetes mellitus which can be lethal, with possible medicolegal implications. However, interpretation of biochemical analyses is difficult because of post-mortem blood alterations involving glucose metabolic pathways. Vitreous humor is better preserved than blood after death, and therefore is preferentially used in thanatochemistry. However, both the lack of experience of most biochemists with this matrix in clinical practice, and the paucity of post-mortem studies make interpretation of post-mortem analyses difficult. This review examines the recent advances in the knowledge of glucose metabolism in vitreous humor, and the methods used for the post-mortem diagnosis of diabetic complications.

scholarly journals Trypanosoma cruzi meningoencephalitis and myocarditis in a patient with acquired immunodeficiency syndrome

1993 ◽  
Vol 35 (2) ◽  
pp. 205-208 ◽  
Author(s):  
Ademir Rocha ◽  
Marcelo S. Ferreira ◽  
Sergio A. Nishioka ◽  
Marcos Silva ◽  
Marcius K. N. Burgarelli ◽  
...  
Keyword(s):  
Human Immunodeficiency Virus ◽  
Differential Diagnosis ◽  
Chagas Disease ◽  
Acquired Immunodeficiency Syndrome ◽  
The Other ◽  
Post Mortem ◽  
Immunodeficiency Virus ◽  
Acquired Immunodeficiency ◽  
Immunodeficiency Syndrome ◽  
Male Heterosexual

We report the case of a 52-year-old male heterosexual patient with acquired immunodeficiency syndrome (AIDS) and reactivation of Chagas' disease manifested by meningoencephalitis and myocarditis, diagnosed post-mortem. Unexplained reactivation of Chagas' disease should be included among the diagnostic criteria of AIDS in human immunodeficiency virus positive patients. On the other hand, AIDS should be considered in the differential diagnosis of patients with unexplained reactivation of Chagas' disease.

Analysis of hypoxanthine and lactic acid levels in vitreous humor for the estimation of post-mortem interval (PMI) using LC–MS/MS

2019 ◽  
Vol 299 ◽  
pp. 135-141 ◽  
Author(s):  
Ahra Go ◽  
Geunae Shim ◽  
Jiwon Park ◽  
Jinwoo Hwang ◽  
Mihyun Nam ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Vitreous Humor ◽  
Post Mortem ◽  
Post Mortem Interval

scholarly journals “2n Analytical Platform” To Update Procedures in Thanatochemistry: Estimation of Post Mortem Interval in Vitreous Humor

2019 ◽  
Vol 91 (11) ◽  
pp. 7025-7031 ◽  
Author(s):  
Roberta Risoluti ◽  
Silvia Canepari ◽  
Paola Frati ◽  
Vittorio Fineschi ◽  
Stefano Materazzi
Keyword(s):  
Vitreous Humor ◽  
Post Mortem ◽  
Post Mortem Interval

Use of entomotoxicology in estimating post-mortem interval and determining cause of death

2017 ◽  
Vol 295 ◽  
pp. 56-63
Author(s):  
Joanna Stojak ◽  
Keyword(s):  
Cause Of Death ◽  
Current Knowledge ◽  
The Body ◽  
Toxic Substances ◽  
Post Mortem ◽  
Toxicological Analysis ◽  
Post Mortem Interval ◽  
The Impact

Entomotoxicology allows the estimation of the post-mortem interval and the determination of the cause of death in cases in which the corpse has decomposed and the tissues necessary for toxicological analysis are no longer available. Obtaining information about toxic substances potentially present in the body is possible by isolation of larvae and pupae of true flies (Diptera) and/or adult forms of, e.g., beetles (Coleoptera) present on or near the corpse. This article was intended to summarize the current knowledge in the field of entomotoxicology, including examples from the literature, and to present the impact of selected toxic substances and medicines on the development of necrophagous larvae of insects.

scholarly journals Flies Do Not Jump to Conclusions: Estimation of the Minimum Post-Mortem Interval for a Partly Skeletonized Body Based on Larvae of Phormia regina (Diptera: Calliphoridae)

Insects ◽  
2021 ◽  
Vol 12 (4) ◽  
pp. 294
Author(s):  
Senta Niederegger ◽  
Gita Mall
Keyword(s):  
Forensic Entomology ◽  
Female Body ◽  
The Other ◽  
Phormia Regina ◽  
Post Mortem ◽  
Post Mortem Interval ◽  
Other Hand

Skeletonization is often perceived as an indicator of long post-mortem intervals. The finding of feeding larvae of first colonizers, on the other hand, indicates days. We present a case in which both findings were present. Larvae of Phormia regina, aged 9 days, and skeletonization of the head and part of the thorax were both found on an unidentified female body. Identification of dentures eventually led to resolution of the case and a confession, which settled the seeming contradiction in favor of forensic entomology.

Amoebiasis as a Cause of Death in a Scottish Resident

1981 ◽  
Vol 26 (4) ◽  
pp. 350-351 ◽  
Author(s):  
G. P. Edlin
Keyword(s):  
Ulcerative Colitis ◽  
Differential Diagnosis ◽  
Abdominal Pain ◽  
Cause Of Death ◽  
Entamoeba Histolytica ◽  
Elderly Woman ◽  
Post Mortem ◽  
Provisional Diagnosis ◽  
Colonic Ulceration

An elderly woman, resident throughout her life in Scotland presented with abdominal pain and diarrhoea. A provisional diagnosis of ulcerative colitis was made on sigmoidoscopy. At post mortem Entamoeba Histolytica was demonstrated in considerable numbers in the mucosal ulcers. It would appear though extremely rare that amoebiasis should be considered in the differential diagnosis of colonic ulceration.

Biochemical correction factors to estimation of post-mortem interval in vitreous humor

2017 ◽  
Vol 25 (2) ◽  
pp. 201-204 ◽  
Author(s):  
Gemma Prieto-Bonete ◽  
Isabel Legaz ◽  
Cristina Pérez-Martínez ◽  
María D. Pérez-Cárceles ◽  
Aurelio Luna
Keyword(s):  
Vitreous Humor ◽  
Post Mortem ◽  
Correction Factors ◽  
Post Mortem Interval

scholarly journals Investigations on Arthropods Associated with Decay Stages of Buried Animals in Italy

Insects ◽  
2021 ◽  
Vol 12 (4) ◽  
pp. 311
Author(s):  
Teresa Bonacci ◽  
Federica Mendicino ◽  
Domenico Bonelli ◽  
Francesco Carlomagno ◽  
Giuseppe Curia ◽  
...  
Keyword(s):  
Experimental Study ◽  
Experimental Investigation ◽  
Decay Rate ◽  
Southern Italy ◽  
The Other ◽  
Post Mortem ◽  
Post Mortem Interval ◽  
Arthropod Fauna ◽  
Pig Carcasses ◽  
Deep Pits

Burial could be used by criminals to conceal the bodies of victims, interfering with the succession of sarcosaprophagous fauna and with the evaluation of post-mortem interval. In Italy, no experimental investigation on arthropods associated with buried remains has been conducted to date. A first experimental study on arthropods associated with buried carcasses was carried out in a rural area of Arcavacata di Rende (Cosenza), Southern Italy, from November 2017 to May 2018. Six pig carcasses (Susscrofa Linnaeus) were used, five of which were buried in 60-cm deep pits, leaving about 25-cm of soil above each carcass, and one was left above ground. One of the buried carcasses was periodically exhumed to evaluate the effects of disturbance on decay processes and on arthropod fauna. The other four carcasses were exhumed only once, respectively after 43, 82, 133, and 171 days. As expected, the decay rate was different among carcasses. Differences in taxa and colonization of arthropod fauna were also detected in the above ground and periodically exhumed carcasses. In carcasses exhumed only once, no arthropod colonization was detected. The results showed that a burial at about 25 cm depth could be sufficient to prevent colonization by sarcosaprophagous taxa and these data could be relevant in forensic cases involving buried corpses.

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