scholarly journals Corneal Crosslinking in Progressive Keratoconus: Comparison of Dextran-Based and Hydroxypropyl Methylcellulose-Based Riboflavin Solutions Differences in demarcation line depth and 1 yaear outcomes

2019 ◽  
Vol 70 (4) ◽  
pp. 1152-1156
Author(s):  
Miruna Gabriela Burcel ◽  
Catalina Corbu ◽  
Valeria Coviltir ◽  
Vasile Potop ◽  
Mihaela Constantin ◽  
...  
Keyword(s):  
Hydroxypropyl Methylcellulose ◽  
Anterior Segment ◽  
Demarcation Line ◽  
Collagen Crosslinking ◽  
Corneal Crosslinking ◽  
Corneal Collagen Crosslinking ◽  
Myopic Astigmatism ◽  
Line Depth ◽  
Corneal Collagen ◽  
Corneal Thinning

Keratoconus is a progressive ectatic disorder characterised by irregular myopic astigmatism and loss of visual acuity due to corneal thinning. Corneal collagen crosslinking is the treatment recognised to stop the progression of keratoconus. Our study evaluates and compares visibility and depth of the stromal demarcation line after corneal collagen crosslinking using anterior segment optical coherence tomography between two groups:crosslinking with dextran-based and hydroxypropyl methylcellulose-based riboflavin solutions. Our work proved a better visibility and a deeper demarcation line when we used HPMC-based riboflavin. Also the study revealed that HPMC-based riboflavin is associated with better biomechanical outcomes than dextran-based riboflavin.

Experimental and morphological reasoning for the use of corneal crosslinking during keratoplasty in small domestic animals

2020 ◽  
Vol 1 (12) ◽  
pp. 12-21
Author(s):  
N. A. Slesarenko ◽  
◽  
A. G. Shilkin ◽  
U. E. Lukashina ◽  
◽  
...  
Keyword(s):  
Postoperative Period ◽  
Clinical Observation ◽  
Corneal Stroma ◽  
Collagen Matrix ◽  
Domestic Animals ◽  
Demarcation Line ◽  
Collagen Crosslinking ◽  
Corneal Crosslinking ◽  
Corneal Collagen Crosslinking ◽  
Corneal Collagen

The article reflects the influence of corneal collagen crosslinking on changes in the morphofunctional signs of the corneal stroma. Data on changes in the anterior layers of the stroma, which are expressed by a compact packing of fibers without signs of even minimal edema, as well as a demarcation line separating the area of impact from the indifferent zone, are scientifically substantiated. Clinical observation of cats and dogs after keratoplasty using a crosslinking modified cornea showed the most favorable course of the postoperative period which was expressed in an increase in the resistance of the collagen matrix of the donor tissue to collagenases which is especially important when using large and giant transplants.

scholarly journals Corneal Collagen Cross-Linking Mushroom Shape Demarcation Line Profile After Limited Bowman’s Membrane Removal by Phototherapeutic Keratectomy

2015 ◽  
Vol 9 (1) ◽  
pp. 17-19 ◽  
Author(s):  
George D Kymionis ◽  
Michael A Grentzelos ◽  
Nektarios E Klados ◽  
Niki A Xanthopoulou ◽  
Theodore A Paraskevopoulos ◽  
...  
Keyword(s):  
Line Profile ◽  
Anterior Segment ◽  
Cross Linking ◽  
Demarcation Line ◽  
Phototherapeutic Keratectomy ◽  
Early Postoperative Complications ◽  
One Year ◽  
Line Depth ◽  
Collagen Cross Linking ◽  
Corneal Collagen

Purpose :To report a corneal collagen cross-linking (CXL) mushroom shape demarcation line profile after limited Bowman’s membrane removal by phototherapeutic keratectomy (PTK).Methods :Case report.Results :A twenty-one-year-old male with progressive keratoconus underwent mechanical epithelial debridement (at an 8.5 mm zone) followed by PTK (at a 5.0 mm zone and in a 10 μm depth) and CXL. No intra- or early postoperative complications were found. Evaluation of the corneal stromal demarcation line depth using anterior segment optical coherence tomography revealed a mushroom shape profile.Conclusion :It seems that removal of the Bowman’s layer leads to greater depth of the corneal stromal demarcation line.

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