SINGLE-PORT VIDEO-ASSISTED THORACOSCOPIC LOBECTOMIES IN SURGICAL TREATMENT FOR LUNG CANCER

2017 ◽  
Vol 63 (3) ◽  
pp. 421-427
Author(s):  
Andrey Arsenev ◽  
A. Zagryadskikh ◽  
V. Gelfond ◽  
K. Gagua ◽  
K. Kostitsyn ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Single Port ◽  
Operating Time ◽  
Chest Drain ◽  
Lung Cancer Patients ◽  
Cancer Management ◽  
Video Assisted ◽  
Surgical Methods ◽  
The Mean ◽  
Thoracoscopic Procedure

This paper summarizes recent Russian and international literature describing endoscopic surgical methods in lung cancer management, particularly, video-assisted lung anatomic resection with different approaches. Own experience of 72 video-assisted single-port lobectomies of stage I-II lung cancer patients is presented. The mean operating time in the second part of the learning curve (40 last procedures) was 90.3, statistically not different from the time of open procedure. Mean blood loss was 98,3 ml. Mean number of lymph nodes was similar in video-assisted single port and open group (14,2 vs 14,8). The conversion rate was 2,8% (2 cases). Only 5 (6,9%) non-lethal complication were associated with thoracoscopic procedure -pneumonia and 4 cases of arrhythmias. The duration of air leak was 2,3 days. The duration of chest drain use was 4,6 days. Postoperative pain was minimal, pain-killers were used not more than 2-3 days after surgery. Patients were ready to be discharges in 5, 8 days.

scholarly journals Single-port Video-Assisted Thoracic Surgery for Lung Cancer

2013 ◽  
Vol 46 (4) ◽  
pp. 299-301 ◽  
Author(s):  
Do Kyun Kang ◽  
Ho Ki Min ◽  
Hee Jae Jun ◽  
Youn Ho Hwang ◽  
Min Kyun Kang
Keyword(s):  
Lung Cancer ◽  
Thoracic Surgery ◽  
Single Port ◽  
Video Assisted Thoracic Surgery ◽  
Video Assisted

Extended administration of oral etoposide and oral cyclophosphamide for the treatment of advanced non-small-cell lung cancer: a Southwest Oncology Group study.

1993 ◽  
Vol 11 (8) ◽  
pp. 1598-1601 ◽  
Author(s):  
S M Grunberg ◽  
J Crowley ◽  
R Livingston ◽  
I Gill ◽  
S K Williamson ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Stage Iv ◽  
Complete Response ◽  
Small Cell ◽  
Small Cell Lung ◽  
Lung Cancer Patients ◽  
Southwest Oncology Group Study ◽  
The Mean

PURPOSE We designed an all-oral regimen of etoposide and cyclophosphamide for use in advanced non-small-cell lung cancer. PATIENTS AND METHODS Eligible patients were chemotherapy-naive and had histologically confirmed assessable or measurable stage IV non-small-cell lung cancer. Patients received etoposide 50 mg/m2/d orally days 1 through 14 and cyclophosphamide 50 mg/m2/d orally days 1 through 14 every 28 days. Doses on later cycles were adjusted for myelosuppression. RESULTS Sixty-six patients (64 eligible patients) received 192 cycles of oral extended etoposide/cyclophosphamide therapy (median, two cycles; range, zero to 15). Therapy was well tolerated with the mean dose per cycle being 104% of the originally scheduled dose. Two patients (3%) achieved a complete response and six (9%) achieved a partial response. Leukopenia, anemia, nausea/vomiting, and alopecia were the most common toxicities. Median survival was 6 months, and the 1-year survival rate was 25.6%, comparable to more intensive treatments. CONCLUSION Oral extended etoposide/cyclophosphamide is a well-tolerated alternative for the treatment of stage IV non-small-cell lung cancer and can be used as a basis for the design of further outpatient regimens.

scholarly journals Seasonal Variation in Physical Activity among Preoperative Patients with Lung Cancer Determined Using a Wearable Device

2020 ◽  
Vol 9 (2) ◽  
pp. 349 ◽  
Author(s):  
Sunga Kong ◽  
Hye Yun Park ◽  
Danbee Kang ◽  
Jae Kyung Lee ◽  
Genehee Lee ◽  
...  
Keyword(s):  
Physical Activity ◽  
Lung Cancer ◽  
Vigorous Physical Activity ◽  
Winter Season ◽  
Wearable Device ◽  
Lung Cancer Patients ◽  
Cardiorespiratory Function ◽  
The Mean ◽  
Temperature Levels ◽  
Autumn And Winter

We aim to examine how season and temperature levels affect physical activity using a wearable device among patients scheduled to undergo surgical resection of lung cancer. Physical activity (PA) data from the wearable device were analyzed by seasons for 555 preoperative lung cancer patients from the CATCH-LUNG cohort study. The seasons were divided into spring, summer, autumn, and winter using the study enrollment date before surgery. The overall mean (SD) age was 61.1 (8.9) years, and the mean (SD) daily steps at each season were 11,438 (5922), 11,147 (5065), 10,404 (4403), and 8548 (4293), respectively. In the fully-adjusted models, patients in the winter season had 27.04% fewer daily steps (95% CI = −36.68%, −15.93%) and 35.22% less time spent performing moderate to vigorous physical activity (MVPA) compared to patients in the spring. The proportion of participants with over 8000 steps and duration of MVPA were significantly lower in the winter than the spring. In particular, daily steps had a negative linear association with wind chill temperature in patients who lived in Seoul. In conclusion, PA was significantly lower in the winter and it was more robust in patients who had a low cardiorespiratory function.

scholarly journals F-112 * PERFORMING VIDEO-ASSISTED THORACOSCOPIC LOBECTOMIES IN LUNG CANCER PATIENTS REDUCES ONE-YEAR HOSPITAL ADMITTANCE

2014 ◽  
Vol 18 (suppl 1) ◽  
pp. S29-S29 ◽  
Author(s):  
L. Konge ◽  
L. O. Laursen ◽  
H. J. Hansen ◽  
T. Jensen ◽  
J. Ravn ◽  
...  
Keyword(s):  
Lung Cancer ◽  
Cancer Patients ◽  
Lung Cancer Patients ◽  
Video Assisted ◽  
One Year

Brain metastasis in lung cancer: Are there any predictive risk factors?

2020 ◽  
Vol 38 (15_suppl) ◽  
pp. e21740-e21740
Author(s):  
Salma Ait Batahar
Keyword(s):  
Lung Cancer ◽  
Brain Metastasis ◽  
Brain Metastases ◽  
Cancer Patients ◽  
Control Group ◽  
Lung Cancer Patients ◽  
Poorly Differentiated Carcinoma ◽  
Poorly Differentiated ◽  
The Mean ◽  
The Moment

e21740 Background: Lung cancer is the first cause of death by cancer worldwide. Brain metastases in lung cancer are associated to an even poorer prognosis of this cancer. Identifying patients with a higher risk of developing brain cancer may help their prognosis by including systematic brain radiotherapy to their treatment. But what are risk factors of brain metastasis occurrence in lung cancer patients? Methods: To answer this question, we conducted a case control study comparing two groups of lung cancer patients. The cases group included 35 lung cancer patients with brain metastasis at the moment of diagnosis while the control group was made of 49 lung cancer patient with no brain metastasis at the moment of diagnosis. Many parameters were compared between the two groups such as: professional exposure, type and duration of smoking, medical history, clinical and radiological presentation as well as the histological type of the carcinoma. Results: The mean age was 56 for the cases group and 61 for the control group. Nonsmokers represented 14% in the cases group and 4% in the control group. The average smoking was 34 pack-year for the cases group and 31 pack-year for the control group and in both groups 51% of patients smoked a mixture of tobacco and Cannabis. 36% of the control group patients had an exposure to a professional carcinogen while 48% of the cases group patients had one. Digital clubbing was found in 62% of cases group patients and in 51% of the control group patients. 17% of the cases group patients had two more metastases outside the lungs and other than the brain ones while this rate was only 6% for the control group patients. The mean level of LDH (Lactate Dehydrogenase) was 340 U/L for the cases group and 342 U/L for the control group while the CRP (C- reactive protein) one was 78 mg/L for the cases group and 59 mg/L for the control group. The main histological type found in both groups was Adenocarcinoma (25% in the cases group and 18% in the control group) followed by the poorly differentiated carcinoma in the cases group and the squamous cell carcinoma in the control group. Small cell carcinoma was found in 5% of the patients with brain metastases and in 8% of the patients without brain metastases. Conclusions: Patients with brain metastases have a higher professional carcinogens exposure, a higher percentage of nonsmokers, more digital clubbing, and higher CRP levels than patients with no brain metastases. They also have more than one metastasis at the moment of the diagnosis and the predominant histological types are Adenocarcinoma and poorly differentiated carcinoma.

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