scholarly journals Development and validation of a registry-based definition of eosinophilic esophagitis in Denmark

2013 ◽  
Vol 19 (4) ◽  
pp. 503 ◽  
Author(s):  
Evan S Dellon
2012 ◽  
Vol 142 (5) ◽  
pp. S-432
Author(s):  
Evan S. Dellon ◽  
Rune Erichsen ◽  
Lars Pedersen ◽  
Nicholas J. Shaheen ◽  
John A. Baron ◽  
...  

2018 ◽  
Vol 31 (6) ◽  
pp. 321 ◽  
Author(s):  
Milena Paneque ◽  
Catarina Costa ◽  
Carolina Lemos ◽  
Miguel Alves-Ferreira ◽  
Jorge Sequeiros ◽  
...  

Introduction: The lack of tools for quality assessment of genetic counselling is recognized in national and international studies. The correlation of quality of healthcare practice with greater satisfaction of patients and affected families is also well established. The present study describes the development and validation of the first Portuguese scale for quality assessment of genetic counselling practice. It encompasses a proposal of a new tool for the evaluation of the process by professionals.Material and Methods: The definition of an initial pool of items and their organization was based on a literature review and identification of the main genetic counselling dimensions as well as the theoretical dimensions of the Reciprocal Engagement Model. After a pre-test validation the scale was submitted to psychometric validation using a sample of 30 participants who evaluated 81 genetic counselling sessions.Results: Based on statistical and empirical criteria the best items were selected. The final 50 items- version comprises five dimensions: education, counselees’ characteristics and decision-making, therapeutic relationship, effects of the process on the counselees andservices organization.Discussion: Results showed consistent psychometric properties of the scale supported on theoretical and practice concepts of genetic counseling. The reduced number of participants involved in psychometric validation is a limitation of the study, which reflected thereduced number of professionals in genetic healthcare services.Conclusion: The scale proposed at this study is a novel and multidimensional instrument that aimed to contribute to the improvement of genetic counselling practice in Portugal.


2004 ◽  
Vol 7 (1) ◽  
pp. 5-16 ◽  
Author(s):  
Beverly Barrett Dahms

Gastroesophageal reflux disease (GERD) is a common condition in infants and children and has many clinical mimics. Most pediatric pathology departments process many mucosal biopsies from the proximal gastrointestinal tract to evaluate the presence or absence of reflux esophagitis. Since this subject was last reviewed in the 1997 edition of Perspectives in Pediatric Pathology devoted to gastrointestinal diseases in children (Dahms BB. Reflux esophagitis and sequelae in infants and children. In: Dahms BB, Qualman SJ, eds. Gastrointestinal Disease. Perspectives in Pediatric Pathology, vol. 20. Basel: Karger, 1997;14–34), progress in the field has allowed recognition of additional presenting symptoms and treatments of GERD. Histologic criteria for diagnosing reflux esophagitis have not changed. However, the entity of eosinophilic esophagitis has emerged since 1997 and has been defined well enough to allow it to be distinguished from reflux esophagitis, with which it was probably previously confused. Refinements (though not simplification!) in the definition of Barrett esophagus are still in evolution. This review will summarize these newer concepts and briefly review the standards of diagnosis of reflux esophagitis.


Author(s):  
Lutz Göcke ◽  
Robin Weninger

AbstractEvery venture is developed under high uncertainty and causal ambiguity. A large majority of digital startups leverage the lean startup approach to validate the attractiveness of their venture, to reduce avoidable investments of scarce resources, and to structure the venturing process. Digital entrepreneurs highlight that prioritization and the definition of MVPs are two challenges that entrepreneurs face when applying the lean startup approach. We provide support on these particular challenges through a structured approach—the venture pyramid—to (in)validate digital business models in the face of high uncertainty. Furthermore, we map different types of digital business models with patterns of minimum viable products to inspire digital entrepreneurs and scientists alike. To illustrate our thoughts, we have developed two case studies of German startups that applied a process of rigorous iteration and learning to their venturing processes.


2019 ◽  
Vol 121 (10) ◽  
pp. 1166-1177 ◽  
Author(s):  
Louise Seconda ◽  
Julia Baudry ◽  
Philippe Pointereau ◽  
Camille Lacour ◽  
Brigitte Langevin ◽  
...  

AbstractIn the current context of unsustainable food systems, we aimed to develop and validate an index, the sustainable diet index (SDI), assessing the sustainability of dietary patterns, including multidimensional individual indicators of sustainability. Based on the FAO’s definition of sustainable diets, the SDI includes seven indicators categorised into four standardised sub-indexes, respectively, environmental, nutritional, economic and sociocultural. The index (range: 4–20) was obtained by summing the sub-indexes. We computed the SDI for 29 388 participants in the NutriNet-Santé cohort study, estimated its validity and identified potential socio-demographic or lifestyle differences across the SDI quintile. In our sample, the SDI (mean=12·10/20; 95 % CI 12·07, 12·13) was highly correlated to all the sub-indexes that exerted substantial influence on the participants’ ranking. The environmental and economical sub-indexes were the most and less correlated with the SDI (Pearson R2 0·66 and 0·52, respectively). Dietary patterns of participants with a high SDI (considered as more sustainable) were concordant with the already published sustainable diets. Participants with high SDI scores were more often women (24 %), post-secondary graduates (22 %) and vegetarians or vegans (7 %), without obesity (16 %). Finally, the SDI could be a useful tool to easily assess the sustainability-related changes in dietary patterns, estimate the association with long-term health outcomes and help guide future public health policies.


2020 ◽  
Vol 39 (3) ◽  
pp. 306-323
Author(s):  
J.A. Yogalakshmi ◽  
M.V. Supriya

PurposeThe aim of the current study was to develop and validate a measure for identifying talent in the workplace. This is a gap long identified by researchers in this field.Design/methodology/approachHinkins methodology was adopted for the establishment of a psychometrically sound measure. A 16-item scale for assessing the construct was developed. The reliability and validity were established by analyzing content adequacy, convergent validity, divergent validity and external validity. Primary data were collected from employees signaled as talent by their organization.FindingsThe study yielded a six-factor structure scale for the construct. These factors accounted for 66.8 percent of observed variance. All six dimensions, namely, calling orientation, critical insight, continuous learning, collaboration, cohesiveness and challenge drive established acceptable reliability and validity.Social implicationsThe research provides a precise definition of the talent construct. Identification and retention of individuals with a high talent quotient is a critical challenge to organizations. Identifying talent is made possible through this measurement scale.Originality/valueThis research made an attempt to develop a reliable and valid measurement scale for the talent construct. The scale provides a precise definition of the talent construct. This simple sound scale could be useful at both the individual and organizational levels. It helps individuals to identify and focus on critical areas for achieving talent status. Organizations benefit through better human resource management practice. Identification and retention of talent are essential to career management. Overall, it also satisfies the urgent need in talent management research for a clear definition of the talent construct.


2021 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Girish Hiremath ◽  
Lili Sun ◽  
Hernan Correa ◽  
Sari Acra ◽  
Margaret H. Collins ◽  
...  

Author(s):  
Cristian Molla Esparza ◽  
Pablo Nájera ◽  
Emelina López-González ◽  
Josep-Maria Losilla

“Sexting” is generally defined as the exchange of sexual media content via the internet. However, research on this topic has underscored the need to seek greater consensus when considering different conceptual elements that make up this definition. The aim of this study was to develop and validate an instrument for measuring sexting among adolescents, in order to cover a gap identified in the previous literature. The Adolescent Sexting Scale (A-SextS for short) was developed for validation on a sample of 579 Spanish secondary school pupils between the ages of 11 and 18. Evidence for face, content, concurrent, and criterion validity were assessed. A comprehensive set of 64 items, covering six defining characteristics of sexting (e.g., actions, recipient, media format, degree of sexual explicitness), was constructed after conducting an extensive literature review, two discussion groups, and a pilot study. Sexting prevalence rates measured by A-SextS were mostly concurrent with those found in previous studies. A-SextS subscales produced statistically significant positive associations with pornography consumption and physical sexual intercourse. The study shows that A-SextS can be an integrating instrument that facilitates a rigorous and comprehensive assessment of adolescent sexting experiences, as well as the formulation of an operationalized definition of the practice of sexting.


2020 ◽  
pp. 251512742097517
Author(s):  
Luciana Padovez Cualheta ◽  
Gardenia da Silva Abbad

Entrepreneurship education outcomes have been poorly evaluated. Previous research focused mostly on subjective measures like entrepreneurial intention that does not necessarily turn into behavior, and have mostly used self-perception questionnaires. Learning and competence results have been under researched. Therefore, the use of situational judgment tests to assess entrepreneurship education learning outcomes is proposed. This is an exploratory study that presents the development and validation process of situational judgment tests, following twelve steps, including the analysis of course’s materials, focus groups with professors and former students, expert validation, semantic validation, empirical validation, the definition of correction sheets and equivalence tests. The course is presented in details and its goals are defined using a learning taxonomy. Results present the three situational judgment tests that were developed and the correction sheets that can be used to guarantee correction in an objective manner. The situational tests developed in this study can be used to evaluate courses with similar goals and the development and validation process can be adopted to evaluate other courses.


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