Habb-e-Qooqaya: A Potent Herbo‑Medicinal Formulation for Shaqeeqa (Migraine)–A Review

Traditional Chinese medicine is one of the oldest medical systems in the world and has its unique principles and theories in the prevention and treatment of human diseases, which are achieved through the interactions of different types of materia medica in the form of Chinese medicinal formulations. GZZSZTW, a classical and effective Chinese medicinal formulation, was designed and created by professor Bailing Liu who is the only national medical master professor in the clinical research field of traditional Chinese medicine and skeletal diseases. GZZSZTW has been widely used in clinical settings for several decades for the treatment of joint diseases. However, the underlying molecular mechanisms are still largely unknown. In the present study, we performed quantitative proteomic analysis to investigate the effects of GZZSZTW on mouse primary chondrocytes using state-of-the-art iTRAQ technology. We demonstrated that the Chinese medicinal formulation GZZSZTW modulates chondrocyte structure, dynamics, and metabolism by controlling multiple functional proteins that are involved in the cellular processes of DNA replication and transcription, protein synthesis and degradation, cytoskeleton dynamics, and signal transduction. Thus, this study has expanded the current knowledge of the molecular mechanism of GZZSZTW treatment on chondrocytes. It has also shed new light on possible strategies to further prevent and treat cartilage-related diseases using traditional Chinese medicinal formulations.

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Comprehending the Role of Physicians and Counterfeit Medicine in Bangladesh

11th GLOBAL CONFERENCE ON BUSINESS AND SOCIAL SCIENCES - Global Conference on Business and Social Sciences Proceeding ◽

10.35609/gcbssproceeding.2021.12(102) ◽

2021 ◽

Vol 12 (1) ◽

pp. 102-102

Author(s):

Farzana Nazera ◽

Assoc. Prof. Dr. Valliappan Raju

Keyword(s):

Bibliometric Analysis ◽

Vital Role ◽

World Health ◽

Flow Diagram ◽

Consultation Service ◽

Counterfeit Medicine ◽

The World ◽

Medicinal Formulation ◽

Health Organization

Counterfeit medicine is a dangerous problem in Bangladesh which make the country's healthcare system in more challenging. For a developing nation like Bangladesh, it is hard to find a perfect solution to curb this problem. According to the World Health Organization (2021), awareness is the key to prevent innocent patient from taking counterfeit medicine. Due to knowledge gap, it's hard for patients to detect the authenticity of medicine because it requires knowledge of medicinal formulation. Physicians of Bangladesh could play a vital role in preventing this counterfeit medicine problem by establishing guidance co-operation relationship with the patients. The study made a literature review of the concept of counterfeit medicine, conducted a bibliometric analysis of counterfeit medicine on Scopus database and provided a relationship flow diagram of prospective guidance relationship between physicians and patients. The study concluded that, this consultation service should be offered by the physicians to the patients and the study expected that, the patient willingly accepts it for getting the safeguard against counterfeit medicine. Keywords: Bibliometric Analysis, Physicians, Patients, Counterfeit Medicine, Bangladesh

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Herbo-medicinal formulation; Marham-e-raal: A potent ointment for acute and chronic wounds – A review

Turkish Journal of Plastic Surgery ◽

10.4103/tjps.tjps_48_18 ◽

2019 ◽

Vol 27 (2) ◽

pp. 77

Author(s):

Waseem Ahmad ◽

SaiyadShah Alam ◽

Zareena Aquil

Keyword(s):

Chronic Wounds ◽

Medicinal Formulation

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A Chinese medicinal formulation ameliorates dextran sulfate sodium-induced experimental colitis by suppressing the activity of nuclear factor-kappaB signaling

Journal of Ethnopharmacology ◽

10.1016/j.jep.2014.12.035 ◽

2015 ◽

Vol 162 ◽

pp. 20-30 ◽

Cited By ~ 13

Author(s):

Siu Wai Tsang ◽

Siu Po Ip ◽

Justin Che-Yuen Wu ◽

Siew-Chien Ng ◽

Ken Kin-Lam Yung ◽

...

Keyword(s):

Dextran Sulfate ◽

Dextran Sulfate Sodium ◽

Experimental Colitis ◽

Nuclear Factor Kappab ◽

Nuclear Factor ◽

Medicinal Formulation

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Using HPLC–DAD and GC–MS Analysis Isolation and Identification of Anticandida Compounds from Gui Zhen Cao Herbs (Genus Bidens): An Important Chinese Medicinal Formulation

Molecules ◽

10.3390/molecules26195820 ◽

2021 ◽

Vol 26 (19) ◽

pp. 5820

Author(s):

Kulsoom Zahara ◽

Yamin Bibi ◽

Saadia Masood ◽

Sobia Nisa ◽

Abdul Qayyum ◽

...

Keyword(s):

High Performance ◽

Gel Chromatography ◽

Bidens Pilosa ◽

Isolation And Identification ◽

Herbal Formulation ◽

Ms Analysis ◽

Array Detection ◽

Medicinal Formulation ◽

Silica Gel Chromatography

Gui Zhen Cao is an herbal formulation that has been documented in Chinese traditional medicine as a remedy for diarrhea, dysentery, inflammation, and toxicity. The sources of this formulation (Bidens pilosa L., Bidens biternata (Lour.) Merr. & Sherff, Bidens bipinnata L.) are also listed in ethnomedicinal reports all over the world. In this study, all these plants are tested for in vitro anticandida activity. A quantitative evaluation of the phytochemicals in all these plants indicated that their vegetative parts are rich in tannins, saponins, oxalates, cyanogenic glycoside and lipids; moreover, the roots have high percentages of alkaloids, flavonoids, and phenols. The results indicated significant anticandida activity, especially for the hexane extract of B. bipinnata leaves which inhibited C. albicans (42.54%), C. glabrata (46.98%), C. tropicalis (50.89%), C. krusei (40.56%), and C. orthopsilosis (50.24%). The extract was subjected to silica gel chromatography and 220 fractions were obtained. Purification by High Performance Liquid Chromatography with Diode-Array Detection (HPLC–DAD) and Gas Chromatography tandem Mass Spectrometry (GC-MS/MS) analysis led to the identification of two anticandida compounds: dehydroabietic and linoleic acid having an inhibition of 85 and 92%, respectively.

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