scholarly journals Recent advances in copper-catalyzed C–H bond amidation

2015 ◽  
Vol 11 ◽  
pp. 2209-2222 ◽  
Author(s):  
Jie-Ping Wan ◽  
Yanfeng Jing
Keyword(s):  
Functional Groups ◽  
Organic Synthesis ◽  
Recent Progress ◽  
Bond Formation ◽  
Carbon Sources ◽  
Copper Catalysis ◽  
Recent Advances

Copper catalysis has been known as a powerful tool for its ubiquitous application in organic synthesis. One of the fundamental utilities of copper catalysis is in the C–N bond formation by using carbon sources and nitrogen functional groups such as amides. In this review, the recent progress in the amidation reactions employing copper-catalyzed C–H amidation is summarized.

Recent Advances in C–Br Bond Formation

Synlett ◽  
2021 ◽  
Author(s):  
Ying-Yeung Yeung ◽  
Jonathan Wong
Keyword(s):  
Organic Synthesis ◽  
Aromatic Compounds ◽  
Bond Formation ◽  
Cross Coupling ◽  
Catalytic Site ◽  
Atom Transfer ◽  
Bond Forming ◽  
Recent Advances ◽  
Catalytic Asymmetric ◽  
Site Selective

AbstractOrganobromine compounds are extremely useful in organic synthesis. In this perspective, a focused discussion on some recent advancements in C–Br bond-forming reactions is presented.1 Introduction2 Selected Recent Advances2.1 Catalytic Asymmetric Bromopolycyclization of Olefinic Substrates2.2 Catalytic Asymmetric Intermolecular Bromination2.3 Some New Catalysts and Reagents for Bromination2.4 Catalytic Site-Selective Bromination of Aromatic Compounds2.5 sp3 C–H Bromination via Atom Transfer/Cross-Coupling3 Outlook

Recent Progress on Radical Decarboxylative Alkylation for Csp3–C Bond Formation

Synthesis ◽  
2017 ◽  
Vol 49 (24) ◽  
pp. 5263-5284 ◽  
Author(s):  
Hongli Bao ◽  
Yajun Li ◽  
Liang Ge ◽  
Munira Muhammad
Keyword(s):  
Carboxylic Acids ◽  
Recent Progress ◽  
Bond Formation ◽  
Stepping Stone ◽  
Recent Advances ◽  
Aliphatic Carboxylic Acids ◽  
Further Development

Radical decarboxylation has emerged as an attractive method for the formation of C–C bonds starting from easily accessible carboxylic acids. In this review, we attempt to bring the readers up to date in this rapidly expanding field. Specifically, we will cover recent advances in Csp3–C bond formation via the radical decarboxylation of aliphatic carboxylic acids and their activated forms, such as N-hydroxyphthalimide esters (NHP esters), alkyl diacyl peroxides, alkyl peresters, and aryliodine(III) dicarboxylates. The scope and limitation of these transformations will be discussed, highlighting gaps in knowledge and research and examining the mechanisms underlying radical decarboxylation. We aim to make this review a stepping stone for further development in this field.1 Introduction2 Aliphatic Carboxylic Acids3 N-Hydroxyphthalimide Esters (NHP Esters)4 Alkyl Diacyl Peroxides5 Alkyl Peresters6 Aryliodine(III) Dicarboxylates7 Conclusion

Recent Advances in Synthesis of Benzazoles via Imines

2020 ◽  
Vol 24 (17) ◽  
pp. 1897-1942
Author(s):  
Ran An ◽  
Mengbi Guo ◽  
Yingbo Zang ◽  
Hang Xu ◽  
Zhuang Hou ◽  
...  
Keyword(s):  
Organic Synthesis ◽  
Recent Progress ◽  
Cascade Reactions ◽  
Biologically Active ◽  
Coupling Reactions ◽  
Condensation Reactions ◽  
Recent Advances

Imines, versatile intermediates for organic synthesis, can be exploited for the preparation of diverse classes of biologically active benzazoles. Because of the special characteristics of the C=N bond, imines can be simultaneously used in the synthesis of 1,3-benzazoles and 1,2-benzazoles. With the development of imine synthesis, a variety of novel cascade reactions for benzazole synthesis have been reported in the last decade. Therefore, there is a strong need to elucidate the recent progress in the formation of various classes of benzazoles, including benzimidazoles, benzoxazoles, benzothiazoles, indazoles, and benzisoxazoles, via imines obtained by condensation reactions or oxidative/ redox coupling reactions

Recent Advances in Metal-Catalyzed Heterocyclic C-P Bond Formation

2020 ◽  
Vol 17 ◽  
Author(s):  
Feng Xu ◽  
Yu Hui
Keyword(s):  
Organic Synthesis ◽  
Recent Progress ◽  
Bond Activation ◽  
Low Cost ◽  
Bond Formation ◽  
Phosphorus Compounds ◽  
Catalytic Systems ◽  
Phosphorus Containing ◽  
Synthetic Pesticides ◽  
Metal Catalyzed

Abstract:: The Phosphorus-containing heterocycles are an important class of compounds in organic chemistry. Because of their potential application in many fields, especially the synthetic pesticides, medicine and catalyst, the Phosphorus-containing heterocycles have attracted continuous attention by organic synthesis scientists. The development of efficient and low-cost catalytic systems is great interest for construction heterocycles C–P bond. Usually, the Phosphorus-containing heterocycles is prepared via direct carbon–hydrogen (C–H) bond activation or pre-functionalized of heterocycles with carbon–hydrogen （ P-H） bond of phosphorus compounds reaction by metal-catalyzed. This review summarizes recent progress in the heterocycles C-P bond formation reactions by metal-catalyzed, which mainly focusing on the discussion of the reaction mechanism. Aims to provide efficient methods for the future synthesis and application in this field.

Quasi-nature catalysis. Rhodium-catalyzed C­C bond formation in air and water

2001 ◽  
Vol 73 (8) ◽  
pp. 1315-1318 ◽  
Author(s):  
Taisheng Huang ◽  
Sripathy Venkatraman ◽  
Yue Meng ◽  
Tien V. Nguyen ◽  
Daniel Kort ◽  
...  
Keyword(s):  
Transition Metal ◽  
Organic Synthesis ◽  
Bond Formation ◽  
Transition Metal Catalysis ◽  
Inert Gas ◽  
Natural Conditions ◽  
Metal Catalysis ◽  
Recent Advances ◽  
Gas Atmosphere

Transition-metal catalysis is out-grown from dry-boxes where the use of inert gas atmosphere and the exclusion of moisture have been essential. Such a restriction undoubtedly imposes limitations in the application of these reactions in organic synthesis and in the recycling of the catalysts. This article discusses some recent advances of rhodium-catalyzed carbon­carbon bond formations under the natural conditions of air and water.

Recent Advances in Transition-Metal-Free Aryl C–B Bond Formation

Synthesis ◽  
2017 ◽  
Vol 49 (21) ◽  
pp. 4719-4730 ◽  
Author(s):  
Ge Meng ◽  
Pengfei Li ◽  
Kai Chen ◽  
Linghua Wang
Keyword(s):  
Transition Metal ◽  
Organic Synthesis ◽  
Bond Formation ◽  
Organometallic Reagents ◽  
Metal Free ◽  
Arylboronic Acids ◽  
Recent Advances ◽  
Conventional Methods

Arylboronic acids and their derivatives are widely used in organic synthesis. Conventional methods for their preparation require either reactive organometallic reagents or transition-metal-mediated processes. In recent years, transition-metal-free reactions for aryl C–B bond formation that obviate preformed organometallic reagents have gained interest and have developed rapidly. These new reactions have shown significant advantages for the preparation of functionalized molecules. In this review, an overview of the recent advances in transition-metal-free aromatic borylation reactions is provided.1 Introduction2 Transition-Metal-Free Transformations of CAr–N Bonds to CAr–B Bonds3 Transition-Metal-Free Transformations of CAr–X Bonds to CAr–B Bonds4 Transition-Metal-Free Transformations of CAr–H Bonds to CAr–B Bonds5 Conclusion

scholarly journals Construction of C-N Bond Via Visible-Light-Mediated Difunctionalization of Alkenes

2021 ◽  
Author(s):  
Bhisma K. Patel ◽  
Tipu Alam ◽  
Amitava Rakshit
Keyword(s):  
Electron Transfer ◽  
Double Bond ◽  
Visible Light ◽  
Functional Groups ◽  
Organic Synthesis ◽  
Bond Formation ◽  
Building Blocks ◽  
Environmental Friendliness ◽  
Visible Light Driven ◽  
Interesting Area

In the last few years, the photo-redox process via single-electron transfer (SET) has received substantial attention for the synthesis of targeted organic compounds due to its environmental friendliness and sustainability. Of late visible-light-mediated difunctionalization of alkenes has gained much attention because of its step economy, which allows the consecutive installation of two functional groups across the C=C bond in a single operation. The construction of N-containing compounds has always been important in organic synthesis. Molecules containing C-N bonds are found in many building blocks and are important precursors to other functional groups. Meanwhile, C-N bond formation via the addition of the C=C double bond is gaining prominence. Therefore, considering the influence and synthetic potential of the C-N bond, here we provide a summary of the state of the art on visible-light-driven difunctionalizations of alkene. We hope that the construction of the C-N bond via visible-light-mediated difunctionalization of alkenes will be useful for medicinal and synthetic organic chemists and will inspire further reaction development in this interesting area.

Recent Progress in Arylation Reactions with Diaryliodonium Salts

2021 ◽  
Vol 25 ◽  
Author(s):  
Dan Wang ◽  
Qian Li ◽  
Mengting Li ◽  
Zhengyin Du ◽  
Ying Fu
Keyword(s):  
Organic Synthesis ◽  
Recent Progress ◽  
Large Range ◽  
Bond Formation ◽  
Cascade Reactions ◽  
High Reactivity ◽  
Synthetic Methods ◽  
Research Progress ◽  
Diaryliodonium Salts

Abstract: In recent years, diaryliodonium salts have been extensively exploited as green, efficient electrophilic arylation reagents in a large range of organic synthesis. These arylating reagents exhibit relatively high reactivity and good selectivity in many transformations. In this review, the synthetic methods towards diaryliodonium salts are described briefly. The research progress in arylation reactions by using diaryliodonium in C-C and carbon-heteroatom bond formation, especially in enantioselective C-C bond formation and cascade reactions, in past ten years is summarized and discussed in detail.

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