(Thio)urea-mediated synthesis of functionalized six-membered rings with multiple chiral centers
2016 ◽
Vol 12
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pp. 462-495
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Keyword(s):
Organocatalysis, now running its second decade of life, is being considered one of the main tools a synthetic chemist has to perform asymmetric catalysis. In this review the synthesis of six-membered rings, that contain multiple chiral centers, either by a ring closing process or by a functionalization reaction on an already existing six-membered ring, utilizing bifunctional (thio)ureas will be summarized. Initially, the use of primary amine-thioureas as organocatalysts for the above transformation is being discussed, followed by the examples employing secondary amine-thioureas. Finally, the use of tertiary amine-thioureas and miscellaneous examples are presented.
2017 ◽
Vol 5
(31)
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pp. 16150-16161
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Keyword(s):
2001 ◽
Vol 57
(2)
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pp. 201-212
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Keyword(s):
2020 ◽
Keyword(s):
2018 ◽
Vol 73
(1)
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pp. 43-74
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Keyword(s):
1980 ◽
Vol 35
(9)
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pp. 1130-1136
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Keyword(s):
1992 ◽
Vol 22
(16)
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pp. 2357-2360
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