scholarly journals Palladium(II)-catalyzed Heck reaction of aryl halides and arylboronic acids with olefins under mild conditions

2013 ◽  
Vol 9 ◽  
pp. 1578-1588 ◽  
Author(s):  
Tanveer Mahamadali Shaikh ◽  
Fung-E Hong
Keyword(s):  
Heck Reaction ◽  
Palladium Complex ◽  
Aryl Halides ◽  
Ambient Conditions ◽  
Heck Reactions ◽  
Reaction Conditions ◽  
Arylboronic Acids ◽  
Mild Conditions ◽  
Pd Complexes ◽  
High Yields

A series of general and selective Pd(II)-catalyzed Heck reactions were investigated under mild reaction conditions. The first protocol has been developed employing an imidazole-based secondary phosphine oxide (SPO) ligated palladium complex (6) as a precatalyst. The catalytic coupling of aryl halides and olefins led to the formation of the corresponding coupled products in excellent yields. A variety of substrates, both electron-rich and electron-poor olefins, were converted smoothly to the targeted products in high yields. Compared with the existing approaches employing SPO–Pd complexes in a Heck reaction, the current strategy features mild reaction conditions and broad substrate scope. Furthermore, we described the coupling of arylboronic acids with olefins, which were catalyzed by Pd(OAc)2 and employed N-bromosuccinimide as an additive under ambient conditions. The resulted biaryls have been obtained in moderate to good yields.

scholarly journals Magnetically recoverable nanostructured Pd complex of dendrimeric type ligand on the MCM-41: Preparation, characterization and catalytic activity in the Heck reaction

2020 ◽  
Vol 43 (1) ◽  
pp. 184-199
Author(s):  
Mohammad Abdollahi-Alibeik ◽  
Najmeh Gharibpour ◽  
Zahra Ramazani
Keyword(s):  
Heck Reaction ◽  
Palladium Complex ◽  
Nanostructured Material ◽  
Magnetic Core ◽  
Aryl Halides ◽  
Heterogeneous Samples ◽  
Recoverable Catalyst ◽  
Ft Ir ◽  
Magnetically Recoverable Catalyst ◽  
Mcm 41

AbstractA palladium complex of a dendrimer type ligand of aminoethylacrylamide immobilized onto the mesoporous channels of MCM-41 with magnetic core was prepared and characterized using various techniques such as XRD, TEM, BET, FT-IR, TGA, and VSM. The prepared nanostructured material was found as a magnetically recoverable catalyst for Heck reaction of aryl halides and vinylic C–H. The catalyst is easily recoverable with an external magnet and is reusable with different leaching amounts depending to loading of Pd. A hot filtration test was also performed and gave evidence that Palladium in heterogeneous samples can dissolve and then redeposit on the surface of the support material.

scholarly journals Direct Sulfoxidation of Aromatic Methyl Thioethers with Aryl Halides by Copper-Catalyzed C(sp3)–H Bond Activation

Catalysts ◽  
2019 ◽  
Vol 9 (1) ◽  
pp. 105
Author(s):  
Runsheng Xu ◽  
Yueer Zhu ◽  
Feixiang Xiong ◽  
Suli Tong
Keyword(s):  
Bond Activation ◽  
Bond Formation ◽  
Aryl Halides ◽  
Biologically Active ◽  
Mild Conditions ◽  
Methyl Thioethers ◽  
High Yields

A copper-catalyzed direct sulfoxidation reaction by C(sp3)–H bond activation has been developed. Starting from sample aromatic methyl thioethers with aryl halides, versatile biologically-active arylbenzylsulfoxide derivatives were efficiently synthesized in good to high yields under mild conditions. This new methodology provides an economical approach toward C(sp3)–C(sp2) bond formation.

Coupling reaction of Aryl Halides Promoted by NiCl2/PPh3/Sm0

2002 ◽  
Vol 2002 (11) ◽  
pp. 562-563 ◽  
Author(s):  
Xingliang Zheng ◽  
Yongmin Zhang
Keyword(s):  
Functional Groups ◽  
Coupling Reaction ◽  
Aryl Halides ◽  
Efficient Synthesis ◽  
Mild Conditions ◽  
Coupling Reagent ◽  
High Yields

An efficient synthesis of biaryls from various aryl halides has been developed and investigated. The coupling reagent is a catalytic mixture of anhydrous NiCl2 and PPh3 in the presence of metallic samarium. The reaction occurs rapidly under mild conditions, tolerates a variety of functional groups with high yields.

Copper(II)-Catalyzed C–N Coupling of Aryl Halides and N-Nucleophiles Promoted by Quebrachitol or Diethylene Glycol

Synlett ◽  
2019 ◽  
Vol 30 (19) ◽  
pp. 2161-2168
Author(s):  
Fangyu Du ◽  
Qifan Zhou ◽  
Yang Fu ◽  
Yuanguang Chen ◽  
Ying Wu ◽  
...  
Keyword(s):  
Diethylene Glycol ◽  
Functional Group ◽  
Aryl Halides ◽  
Coupling Reactions ◽  
Mild Conditions ◽  
Natural Ligand ◽  
Highly Effective ◽  
High Yields

Herein, we report the natural ligand quebrachitol (QCT) as a promoter for a Cu(II) catalyst, which is highly effective for N-arylation of various amines and related aryl halides. A series of diarylamine derivatives were obtained in high yields by using diethylene glycol (DEG) as both ligand and solvent. The C–N coupling reactions proceed under mild conditions and exhibit good functional group tolerance.

scholarly journals Cs2CO3/[bmim]Br as an Efficient, Green, and Reusable Catalytic System for the Synthesis of N-Alkyl Derivatives of Phthalimide under Mild Conditions

2008 ◽  
Vol 2008 ◽  
pp. 1-4 ◽  
Author(s):  
Alireza Hasaninejad ◽  
Abdolkarim Zare ◽  
Ahmad Reza Moosavi-Zare ◽  
Fatemeh Khedri ◽  
Rahimeh Rahimi ◽  
...  
Keyword(s):  
Ionic Liquid ◽  
Catalytic System ◽  
Reaction Times ◽  
Catalytic Amount ◽  
Conjugate Addition ◽  
Reaction Conditions ◽  
Mild Conditions ◽  
Alkyl Derivatives ◽  
High Yields ◽  
Derivatives Of

Aza-conjugate addition of phthalimide to α,β-unsaturated esters efficiently achieves in the presence of catalytic amount of Cs2CO3 and ionic liquid 1-butyl-3-methylimidazolium bromide ([bmim]Br) under mild reaction conditions (70°C) to afford N-alkyl phthalimides in high yields and relatively short reaction times.

scholarly journals An Efficient Protocol for the Synthesis of Quinoxaline Derivatives at Room Temperature Using Recyclable Alumina-Supported Heteropolyoxometalates

2012 ◽  
Vol 2012 ◽  
pp. 1-8 ◽  
Author(s):  
Diego M. Ruiz ◽  
Juan C. Autino ◽  
Nancy Quaranta ◽  
Patricia G. Vázquez ◽  
Gustavo P. Romanelli
Keyword(s):  
Room Temperature ◽  
Incipient Wetness Impregnation ◽  
Reaction Conditions ◽  
Commercial Alumina ◽  
Mild Conditions ◽  
Quinoxaline Derivatives ◽  
Incipient Wetness ◽  
High Yields ◽  
Catalytic Test

We report a suitable quinoxaline synthesis using molybdophosphovanadates supported on commercial alumina cylinders as catalysts. These catalysts were prepared by incipient wetness impregnation. The catalytic test was performed under different reaction conditions in order to know the performance of the synthesized catalysts. The method shows high yields of quinoxaline derivatives under heterogeneous conditions. Quinoxaline formation was obtained using benzyl,o-phenylenediamine, and toluene as reaction solvent at room temperature. The CuH2PMo11VO40supported on alumina showed higher activity in the tested reaction. Finally, various quinoxalines were prepared under mild conditions and with excellent yields.

Heck reactions of aryl halides with alk-1-en-3-ol derivatives catalysed by a tetraphosphine–palladium complex

2006 ◽  
Vol 20 (12) ◽  
pp. 855-868 ◽  
Author(s):  
Florian Berthiol ◽  
Henri Doucet ◽  
Maurice Santelli
Keyword(s):  
Palladium Complex ◽  
Aryl Halides ◽  
Heck Reactions

ChemInform Abstract: High Yields of Symmetrical Biaryls from Palladium-Catalyzed Homocoupling of Arylboronic Acids Under Mild Conditions.

ChemInform ◽  
2010 ◽  
Vol 28 (23) ◽  
pp. no-no
Author(s):  
K. A. SMITH ◽  
E. M. CAMPI ◽  
W. R. JACKSON ◽  
S. MARCUCCIO ◽  
C. G. M. NAESLUND ◽  
...  
Keyword(s):  
Arylboronic Acids ◽  
Mild Conditions ◽  
Palladium Catalyzed ◽  
High Yields

An Efficient Ultrasonic-Assisted Synthesis of Enol Carbamates via Oxidative Coupling of Formamides with 1,3-Dicarbonyl Compounds

2020 ◽  
Vol 17 (7) ◽  
pp. 507-511
Author(s):  
Jafar Akbari ◽  
Alireza Akbari Meyestani
Keyword(s):  
Oxidative Coupling ◽  
Cuo Nanoparticles ◽  
Reaction Conditions ◽  
Dicarbonyl Compounds ◽  
Butyl Hydroperoxide ◽  
Mild Conditions ◽  
Tert Butyl Hydroperoxide ◽  
Ultrasonic Assisted ◽  
High Yields ◽  
Derivatives Of

Sonochemical oxidative-coupling of formamides with 1,3-dicarbonyl compounds in the corresponding carbamates by CuO nanoparticles as a catalyst and tert-butyl hydroperoxide (TBHP) as an oxidant has been reported. Various derivatives of enol carbamates were synthesized with good to high yields under the optimized reaction conditions. Compared with conventional methods, the main advantage of this method is mild conditions.

Ligand-Free and Regioselectivity of the Heck Reaction Catalyzed by Pd(0) Nanoparticles at Ambient Conditions under Ultrasonic Irradiation

2010 ◽  
Vol 113-116 ◽  
pp. 1675-1678
Author(s):  
Yan Hua Zhang ◽  
E Yu Ji ◽  
Song Tao Chen ◽  
Da Min Tian
Keyword(s):  
Ultrasonic Irradiation ◽  
Heck Reaction ◽  
Xrd Analysis ◽  
Reaction Rates ◽  
Nano Particles ◽  
Ambient Conditions ◽  
Transmission Electron ◽  
Ligand Free ◽  
High Yields

The Heck reaction proceeded in isopropanol under ultrasonic irradiation at ambient temperature (30°C) has been reported in this report. The Heck reaction showed excellent regio- selectivity, enhanced reaction rates, high yields, and the conditions were mild and environmentally friendly. It was found that as a heterogeneous catalyst for the reaction palladium forms nano- particles in-situ, and can be recycled for many times. Transmission electron microscopy (TEM) and X-ray powder diffraction (XRD) analysis characteried the formation of stable, crystalline Pd(0) nanoparticles as catalyst for the reaction.

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