scholarly journals Haptoglobin use and acute kidney injury requiring renal replacement therapy among patients with severe burn injury: a nationwide database study

2019 ◽  
Vol 1 (2) ◽  
pp. 69-75
Author(s):  
Takashi Tagami ◽  
Hiroki Matsui ◽  
Marcus Ong ◽  
Masamune Kuno ◽  
Junya Kaneko ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Renal Replacement Therapy ◽  
Replacement Therapy ◽  
Burn Injury ◽  
Kidney Injury ◽  
Severe Burn ◽  
Database Study ◽  
Nationwide Database ◽  
Severe Burn Injury

scholarly journals Long-Term Outcome After Renal Replacement Therapy in Severe Burns

2020 ◽  
Vol 41 (4) ◽  
pp. 866-870
Author(s):  
Ilmari Rakkolainen ◽  
Kukka-Maaria Mustonen ◽  
Jyrki Vuola
Keyword(s):  
Acute Kidney Injury ◽  
Renal Replacement Therapy ◽  
Replacement Therapy ◽  
Burn Injury ◽  
Kidney Injury ◽  
Term Outcome ◽  
Long Term Outcome ◽  
Discharged Patients

Abstract Acute kidney injury is a common sequela after major burn injury, but only a small proportion of patients need renal replacement therapy. In the majority of patients, need for renal replacement therapy subsides before discharge from the burn center but limited literature exists on long-term outcomes. A few studies report an increased risk for chronic renal failure after burn injury. We investigated the long-term outcome of severely burned patients receiving renal replacement therapy during acute burn injury treatment. Data on 68 severely burned patients who received renal replacement therapy in Helsinki Burn Centre between November 1988 and December 2015 were collected retrospectively. Thirty-two patients survived and remained for follow-up after the primary hospital stay until December 31, 2016. About 56.3% of discharged patients were alive at the end of follow-up. In 81.3% of discharged patients, need for renal replacement therapy subsided before discharge. Two patients received renal replacement therapy for longer than 3 months; however, need for renal replacement therapy subsided in both patients. One patient required dialysis several years later on after the need for renal replacement therapy had subsided. This study showed that long-term need for renal replacement therapy is rare after severe burn injury. In the vast majority of patients, need for renal replacement therapy subsided before discharge from primary care. Acute kidney injury in association with burns is a potential but small risk factor for later worsening of kidney function in fragile individuals.

scholarly journals Coupled-plasma filtration and adsorption for severe burn patients with septic shock and acute kidney injury treated with renal replacement therapy

Burns ◽  
2020 ◽  
Vol 46 (1) ◽  
pp. 190-198 ◽  
Author(s):  
Filippo Mariano ◽  
Zsuzsanna Hollo’ ◽  
Nadia Depetris ◽  
Valeria Malvasio ◽  
Alberto Mella ◽  
...  
Keyword(s):  
Septic Shock ◽  
Acute Kidney Injury ◽  
Renal Replacement Therapy ◽  
Replacement Therapy ◽  
Kidney Injury ◽  
Burn Patients ◽  
Severe Burn ◽  
Plasma Filtration

Acute kidney injury in patients with severe burn injury

2018 ◽  
Author(s):  
Nele Brusselaers ◽  
Eric A. J. Hoste
Keyword(s):  
Acute Kidney Injury ◽  
Burn Injury ◽  
Negative Impact ◽  
Kidney Injury ◽  
Severe Form ◽  
Burn Shock ◽  
Burn Patients ◽  
Severe Burn ◽  
Abdominal Hypertension ◽  
Severe Burn Injury

Acute kidney injury (AKI) occurs in approximately one-quarter of all patients with severe burn injury (as defined by the RIFLE consensus classification), and approximately 3% of paediatric burn patients. Overall, a three- to six-fold higher mortality for burn patients with AKI is observed, depending on the applied definition. When AKI is defined by the sensitive RIFLE classification, median mortality of AKI is approximately 35%. This chapter describes the general pathophysiology of AKI in burns, particularly the severe form of burn shock, and discusses in addition the roles of intra-abdominal hypertension, rhabdomyolysis, and the potentially negative impact of povidone-iodine burn dressing. Finally the definitions used in burn pathology, the prevention of AKI with a discussion of the fluid therapy in burned patients, and the role of renal replacement therapy in these patients is discussed.

scholarly journals The Incidence and Characteristic of Acute Kidney Injury as A Complication of Severe Burn Injury in Patients Receiving Fluid Resuscitation

2013 ◽  
Vol 2 (2) ◽  
pp. 101-107
Author(s):  
Johannes Albert Biben
Keyword(s):  
Acute Kidney Injury ◽  
Burn Injury ◽  
Kidney Injury ◽  
Medical Practitioner ◽  
Medical Decision ◽  
Cochrane Library ◽  
Severe Burn ◽  
Level Of Evidence ◽  
Care Protocol ◽  
Severe Burn Injury

Background: Acute kidney injury is important factor that can increase mortality in patient with severe burn injury. Knowledge about incidence and characteristic of acute kidney injury among severe burned patients will help medical practitioner to establish appropriate medical decision and health care protocol. Method: PubMed, Cochrane Library, and GoogleTM search yielded 12 articles. The articles were screened by inclusion criteria, exclusion criteria, and full text reading. Five remaining articles appraised in regard of validity, importance, and applicability. Result: Incidence of acute kidney injury among severely burned patients varies from 24.4% to 53.3%. According to the study with best level of evidence, a systematic review, the incidence of AKI is 28.8% (95% CI 26.8%-30.7%). AKI can occur early or late, and may progress. Progressive AKI has highest mortality rate. Conclusion: AKI is common complication among patients with severe burn injury. Approximately one- third to half of patients with severe burn injury will develop AKI in the course of the disease. Early clinical assessment and re-evaluation are important in severe burn injury management.

Preoperative Low Serum Albumin Levels Increase the Requirement of Renal Replacement Therapy after Cardiac Surgery

2016 ◽  
Vol 19 (3) ◽  
pp. 123 ◽  
Author(s):  
Orhan Findik ◽  
Ufuk Aydin ◽  
Ozgur Baris ◽  
Hakan Parlar ◽  
Gokcen Atilboz Alagoz ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Regression Analysis ◽  
Cardiac Surgery ◽  
Renal Replacement Therapy ◽  
Serum Albumin ◽  
Replacement Therapy ◽  
Kidney Injury ◽  
Preoperative Serum ◽  
Group I ◽  
Group Ii

<strong>Background:</strong> Acute kidney injury is a common complication of cardiac surgery that increases morbidity and mortality. The aim of the present study is to analyze the association of preoperative serum albumin levels with acute kidney injury and the requirement of renal replacement therapy after isolated coronary artery bypass graft surgery (CABG).<br /><strong>Methods:</strong> We retrospectively reviewed the prospectively collected data of 530 adult patients who underwent isolated CABG surgery with normal renal function. The perioperative clinical data of the patients included demographic data, laboratory data, length of stay, in-hospital complications and mortality. The patient population was divided into two groups: group I patients with preoperative serum albumin levels &lt;3.5 mg/dL; and group II pateints with preoperative serum albumin levels ≥3.5 mg/dL.<br /><strong>Results:</strong> There were 413 patients in group I and 117 patients in group II. Postoperative acute kidney injury (AKI) occured in 33 patients (28.2%) in group I and in 79 patients (19.1%) in group II. Renal replacement therapy was required in 17 patients (3.2%) (8 patients from group I; 9 patients from group II; P = .018). 30-day mortality occurred in 18 patients (3.4%) (10 patients from group I; 8 patients from group II; P = .037). Fourteen of these patients required renal replacement therapy. Logistic regression analysis revealing the presence of lower serum albumin levels preoperatively was shown to be associated with increased incidence of postoperative AKI (OR: 1.661; 95% CI: 1.037-2.661; <br />P = .035). Logistic regression analysis also revealed that DM (OR: 3.325; 95% CI: 2.162-5.114; P = .000) was another independent risk factor for AKI after isolated CABG. <br /><strong>Conclusion:</strong> Low preoperative serum albumin levels result in severe acute kidney injury and increase the rate of renal replacement therapy and mortality after isolated CABG.

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