scholarly journals Frequency and Antimicrobial Susceptibility Pattern of Gram-Negative Bacilli Isolated From Urine Specimens at a Tertiary Care Setting

2022 ◽  
Vol 9 (1) ◽  
pp. 15-19
Author(s):  
Ihsan Ullah ◽  
Aamir Hussain ◽  
Humera Adeeb ◽  
Mubarak Zeb

OBJECTIVES: To find out the frequency and pattern of conventional antibiotic susceptibility of gram-negative bacilli cultured from urine specimens of patients at a tertiary care setting. METHODOLOGY: This study was conducted at the Microbiology Department of Combined Military Hospital Multan from June 2016 to May 2017. The data in this retrospective descriptive study was collected from urine culture records of the Microbiology Department, CMH Multan. Only those urine specimens who revealed positive gram-negative bacilli cultures were included in the study. Drug susceptibility patterns of these isolates were recorded against routinely used antibiotics (e.g. Nitrofurantoin, Imipenem, Sulbactum-cefoperazone, Gentamicin and Ciprofloxacin) and evaluated accordingly. RESULTS: A total of 1703 urine specimens were submitted for culture and antibiotics susceptibility testing during the period of study. A total of 128 specimens showed growth of gram-negative rods. Imipenem (95% sensitivity), Sulbactam- Cefoperazone (88% sensitivity) and Nitrofurantoin (87% sensitivity) were highly effective antibiotics against the cultured gram-negative bacilli in the study. CONCLUSION: This study showed that E. coli is the commonest cause of urinary tract infection (UTIs), followed by Klebsiella and Enterobacter species among gram-negative bacilli in our set up. In-vitro efficacy of Imipenem, Sulbactam- Cefoperazone and Nitrofurantoin was found to be the highest against these gram-negative bacilli as compared to other antimicrobials. On the contrary, in-vitro efficacy of ciprofloxacin and gentamycin was found to be extremely low.

2020 ◽  
Vol 23 ◽  
pp. 26-32
Author(s):  
Hanan H. Balkhy ◽  
Aiman El-Saed ◽  
Majid M. Alshamrani ◽  
Asim Alsaedi ◽  
Wafa Al Nasser ◽  
...  

2011 ◽  
Vol 18 (03) ◽  
pp. 402-406
Author(s):  
MUHAMMAD TAHIR ◽  
MUHAMMAD ALI BHATTI ◽  
AMEER ABDULLAH

Objectives: To evaluate foreign bodies in tracheobronchial tree and effectiveness of the therapeutic use of rigid bronchoscopy in a tertiary care setting. Study Design: Descriptive study. Place and duration of study. This study was carried out at Department of ENT and Head and Neck Surgery, Combined Military Hospital, Rawalpindi from June 2006 to June 2010. Patients and methods: This descriptive study was designed to evaluate the foreign bodies in tracheobronchial tree & effectiveness of the use of rigid bronchoscopy in a tertiary care setting. Sixty two patients underwent initial evaluation by ENT consultants and senior registrars followed by management with rigid bronchoscopy. Results: The most commonly affected age group was under 4 years. Male to female ratio was 3:1. Right main bronchus was affected in 51.61% cases. Most of the foreign bodies removed were organic in nature in 90.32% cases. The success rate for removal with rigid bronchoscopy was achieved in 98.39% cases, with fewer complications and no mortality Conclusions: It may be concluded from this study that early diagnosis & management is essential to prevent morbidity & mortality associated with foreign bodies. Rigid bronchoscopy is the most effective procedure for the removal of foreign bodies in tracheobronchial tree. 


2015 ◽  
Vol 15 (1) ◽  
Author(s):  
Appiah-Korang Labi ◽  
Noah Obeng-Nkrumah ◽  
Naa Addison ◽  
Eric S. Donkor

2013 ◽  
Vol 6 ◽  
pp. P149
Author(s):  
Anoma Siribaddana ◽  
Fariha Sitheeque ◽  
Sonali Surangi ◽  
Srinath Illeperuma ◽  
Dinesh Dassanayaka

2014 ◽  
Vol 14 (1) ◽  
Author(s):  
Prasad Katulanda ◽  
Yasindu C Waniganayake ◽  
Priyanga Ranasinghe ◽  
WM Udai Akalanka Wijetunga ◽  
Mahesh Jayaweera ◽  
...  

2021 ◽  
pp. 65-67
Author(s):  
Hemendra K Sharma ◽  
Niketa Gupta ◽  
Mahesh Yadav ◽  
Aruna Vyas ◽  
Rajni Sharma

Background: Pyogenic infections can be caused by various microorganisms and may co-exist as poly microbial infections which require antibiotic therapy. The inappropriate use of antibiotics has led to major problems of MDRO's contributing to morbidity and mortality. Even though the bacteriological prole of pus samples in many studies remain the same, antimicrobial susceptibility pattern of these isolates has shown a lot of variation. This study was conducted to assess bacteriological prole of pus samples and their antimicrobial susceptibility pattern Materials and Methods:Aretrospective study was carried out from April to June 2021. 540 pus culture aerobic bacterial isolates were included. The samples were cultured on Blood and MacConkey agar. After aerobic incubation at 37oC for 18-24 hrs, organisms were identied by conventional bacteriology methods as per laboratory protocol and antimicrobial susceptibility was tested by Kirby Bauer disc diffusion method as per CLSI 2020 guideline. Results: Out of 540 pus isolates , 452(83.7%)were gram negative bacili and 88(16.3%) were gram positive cocci Pseudomonas spp. 173(31.9%), was most common gram negative isolate while S.. aureus 66(12.19%) was most common Gram positive isolate. Most of gram negative isolates were susceptible to Imipenem and Polymyxin and gram positive isolates to vancomycin and linezolid . Conclusion: To combat resistance irrational use of antibiotics should be avoided. Also regular surveillance helps in implementing better therapeutic strategies to reduce morbidity and mortality


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