A meta-analysis of the effect of psychological intervention on patients with psoriasis

Effectiveness of psychological interventions to improve emotion regulation in youth - a meta-analysis

10.31234/osf.io/3yxcp ◽

2019 ◽

Author(s):

Bettina Moltrecht ◽

Jessica Deighton ◽

Praveetha Patalay ◽

Julian Childs

Keyword(s):

Emotion Regulation ◽

Emotion Dysregulation ◽

Psychological Intervention ◽

Meta Analysis ◽

Age Groups ◽

Effect Sizes ◽

What Works ◽

Large Heterogeneity ◽

Larger Sample

Background: Research investigating the role of emotion regulation (ER) in the development and treatment of psychopathology has increased in recent years. Evidence suggests that an increased focus on ER in treatment can improve existing interventions. Most ER research has neglected young people, therefore the present meta-analysis summarizes the evidence for existing psychosocial intervention and their effectiveness to improve ER in youth. Methods: A systematic review and meta-analysis was conducted according to the PRISMA guidelines. Twenty-one randomized-control-trials (RCTs) assessed changes in ER following a psychological intervention in youth exhibiting various psychopathological symptoms.Results: We found moderate effect sizes for current interventions to decrease emotion dysregulation in youth (g=-.46) and small effect sizes to improve emotion regulation (g=0.36). Significant differences between studies including intervention components, ER measures and populations studied resulted in large heterogeneity. Conclusion: This is the first meta-analysis that summarizes the effectiveness for existing interventions to improve ER in youth. The results suggest that interventions can enhance ER in youth, and that these improvements correlate with improvements in psychopathology. More RCTs including larger sample sizes, different age groups and psychopathologies are needed to increase our understanding of what works for who and when.

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Psychological interventions as an alternative and add-on to antidepressant medication to prevent depressive relapse: systematic review and meta-analysis

The British Journal of Psychiatry ◽

10.1192/bjp.2020.198 ◽

2020 ◽

pp. 1-8

Author(s):

Josefien Johanna Froukje Breedvelt ◽

Maria Elisabeth Brouwer ◽

Mathias Harrer ◽

Maria Semkovska ◽

David Daniel Ebert ◽

...

Keyword(s):

Psychological Intervention ◽

Meta Analysis ◽

Antidepressant Medication ◽

Cochrane Library ◽

Psychological Interventions ◽

Relapse Risk ◽

Increased Risk ◽

Antidepressant Use ◽

Randomised Controlled ◽

Risk Of Relapse

Background After remission, antidepressants are often taken long term to prevent depressive relapse or recurrence. Whether psychological interventions can be a viable alternative or addition to antidepressants remains unclear. Aims To compare the effectiveness of psychological interventions as an alternative (including delivered when tapering antidepressants) or addition to antidepressants alone for preventing depressive relapse. Method Embase, PubMed, the Cochrane Library and PsycINFO were searched from inception until 13 October 2019. Randomised controlled trials (RCTs) with previously depressed patients in (partial) remission where preventive psychological interventions with or without antidepressants (including tapering) were compared with antidepressant control were included. Data were extracted independently from published trials. A random-effects meta-analysis on time to relapse (hazard ratio, HR) and risk of relapse (risk ratio, RR) at the last point of follow-up was conducted. PROSPERO ID: CRD42017055301. Results Among 11 included trials (n = 1559), we did not observe an increased risk of relapse for participants receiving a psychological intervention while tapering antidepressants versus antidepressants alone (RR = 1.02, 95% CI 0.84–1.25; P = 0.85). Psychological interventions added to antidepressants significantly reduced the risk of relapse (RR = 0.85, 95% CI 0.74–0.97; P = 0.01) compared with antidepressants alone. Conclusions This study found no evidence to suggest that adding a psychological intervention to tapering increases the risk of relapse when compared with antidepressants alone. Adding a psychological intervention to antidepressant use reduces relapse risk significantly versus antidepressants alone. As neither strategy is routinely implemented these findings are relevant for patients, clinicians and guideline developers.

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Antenatal psychological intervention for universal prevention of antenatal and postnatal depression: A systematic review and meta-analysis

Journal of Affective Disorders ◽

10.1016/j.jad.2020.04.063 ◽

2020 ◽

Vol 273 ◽

pp. 231-239

Author(s):

Naonori Yasuma ◽

Zui Narita ◽

Natsu Sasaki ◽

Erika Obikane ◽

Junpei Sekiya ◽

...

Keyword(s):

Systematic Review ◽

Postnatal Depression ◽

Psychological Intervention ◽

Meta Analysis ◽

Universal Prevention

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Psychological interventions for positive symptoms in schizophrenia: protocol for a network meta-analysis of randomised controlled trials

BMJ Open ◽

10.1136/bmjopen-2017-019280 ◽

2018 ◽

Vol 8 (3) ◽

pp. e019280 ◽

Cited By ~ 5

Author(s):

Irene Bighelli ◽

Georgia Salanti ◽

Cornelia Reitmeir ◽

Sofia Wallis ◽

Corrado Barbui ◽

...

Keyword(s):

Randomised Controlled Trials ◽

Psychological Intervention ◽

Meta Analysis ◽

Risk Of Bias ◽

Evaluation Framework ◽

Sensitivity Analyses ◽

Controlled Trials ◽

Positive Symptoms ◽

Psychological Treatments ◽

Randomised Controlled

IntroductionThere is rising awareness that we need multidisciplinary approaches integrating psychological treatments for schizophrenia, but a comprehensive evidence based on their relative efficacy is lacking. We will conduct a network meta-analysis (NMA), integrating direct and indirect comparisons from randomised controlled trials (RCTs) to rank psychological treatments for schizophrenia according to their efficacy, acceptability and tolerability.Methods and analysisWe will include all RCTs comparing a psychological treatment aimed at positive symptoms of schizophrenia with another psychological intervention or with a no treatment condition (waiting-list and treatment as usual). We will include studies on adult patients with schizophrenia, excluding specific subpopulations (eg, first-episode patients or patients with psychiatric comorbidities). Primary outcome will be the change in positive symptoms on a published rating scale. Secondary outcomes will be acceptability (dropout), change in overall and negative symptoms of schizophrenia, response, relapse, adherence, depression, quality of life, functioning and adverse events. Published and unpublished studies will be sought through database searches, trial registries and websites. Study selection and data extraction will be conducted by at least two independent reviewers. We will conduct random-effects NMA to synthesise all evidences for each outcome and obtain a comprehensive ranking of all treatments. NMA will be conducted in Stata and R within a frequentist framework. The risk of bias in studies will be evaluated using the Cochrane Risk of Bias tool and the credibility of the evidence will be evaluated using an adaptation of the Grading of Recommendations Assessment, Development and Evaluation framework to NMA, recommended by the Cochrane guidance. Subgroup and sensitivity analyses will be conducted to assess the robustness of the findings.Ethics and disseminationNo ethical issues are foreseen. Results from this study will be published in peer-reviewed journals and presented at relevant conferences.PROSPERO registration numberCRD42017067795.

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Prevention of Eating Disorders at Universities: A Systematic Review and Meta-Analysis

10.31234/osf.io/w59ud ◽

2019 ◽

Author(s):

Mathias Harrer ◽

Sophia Helen Adam ◽

Eva-Maria Messner ◽

Harald Baumeister ◽

Pim Cuijpers ◽

...

Keyword(s):

Systematic Review ◽

Eating Disorders ◽

Eating Disorder ◽

Psychological Intervention ◽

Meta Analysis ◽

Significant Heterogeneity ◽

Drive For Thinness ◽

Eating Disorder Symptoms ◽

Eating Disorder Prevention ◽

Disorder Prevention

Background. Eating problems are highly prevalent among young adults. Universities could be an optimal setting to prevent eating disorders through psychological intervention. As part of the World Mental Health-International College Student initiative, this systematic review and meta-analysis synthesizes data on the efficacy of eating disorder prevention programs targeting university students.Method. A systematic literature search of bibliographical databases (CENTRAL, MEDLINE, PsycINFO) for randomized trials comparing psychological preventive interventions for eating disorders in university students to psychoeducation or inactive controls was performed through October 8th, 2018.Results. Twenty-two studies were included. Eight (36.4%) were rated to have a low risk of bias. The relative risk of developing a subthreshold or full-blown eating disorder was IRR=0.62 (95%CI: 0.44-0.87, n=8; standardized clinical interviews only), indicating a 38% decrease in incidence in the intervention groups compared to controls. Small to moderate between- group effects at post-test were found on self-reported global eating disorder symptoms (g=0.36, 95%CI: 0.25-0.47, n=20), dieting (g=0.47, 95%CI: 0.30- 0.64, n=18), body dissatisfaction (g=0.50, 95%CI: 0.33-0.67, n=14), drive for thinness (g=0.43, 95%CI: 0.27-0.59, n=12), weight concerns (g=0.33, 95%CI: 0.10-0.57, n=13) and affective symptoms (g=0.28, 95%CI: 0.16-0.40, n=14). Effects on bulimia were not significant. Heterogeneity was low to moderate across comparisons.Discussion. Eating disorder prevention on campus can have significant, small-to-moderate effects on eating disorder symptoms and risk factors. Results also suggest that the prevention of subthreshold and full-syndrome eating disorders is feasible using such interventions. More research is needed to identify effects on academic functioning, as well as ways to motivate students to use preventive eating disorder interventions.

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Individual participant data (IPD) meta-analysis of psychological relapse prevention interventions versus control for patients in remission from depression: a protocol

BMJ Open ◽

10.1136/bmjopen-2019-034158 ◽

2020 ◽

Vol 10 (2) ◽

pp. e034158 ◽

Cited By ~ 1

Author(s):

Josefien J F Breedvelt ◽

Fiona C Warren ◽

Marlies E Brouwer ◽

Eirini Karyotaki ◽

Willem Kuyken ◽

...

Keyword(s):

Data Storage ◽

Cox Regression ◽

Psychological Intervention ◽

Meta Analysis ◽

Antidepressant Medication ◽

Cochrane Central Register ◽

Individual Participant Data ◽

Recurrent Depression ◽

Effective Interventions ◽

Individual Participant

IntroductionPsychological interventions and antidepressant medication can be effective interventions to prevent depressive relapse for patients currently in remission of depression. Less is known about overall factors that predict or moderate treatment response for patients receiving a psychological intervention for recurrent depression. This is a protocol for an individual participant data (IPD) meta-analysis which aims to assess predictors and moderators of relapse or recurrence for patients currently in remission from depression.Methods and analysisSearches of PubMed, PsycINFO, Embase and Cochrane Central Register of Controlled Trials were completed on 13 October 2019. Study extractions and risk of bias assessments have been completed. Study authors will be asked to contribute IPD. Standard aggregate meta-analysis and IPD analysis will be conducted, and the outcomes will be compared with assess whether results differ between studies supplying data and those that did not. IPD files of individual data will be merged and variables homogenised where possible for consistency. IPD will be analysed via Cox regression and one and two-stage analyses will be conducted.Ethics and disseminationThe results will be published in peer review journals and shared in a policy briefing as well as accessible formats and shared with a range of stakeholders. The results will inform patients and clinicians and researchers about our current understanding of more personalised ways to prevent a depressive relapse. No local ethics approval was necessary following consultation with the legal department. Guidance on patient data storage and management will be adhered to.PROSPERO registration numberCRD42019127844.

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Technology-based parenting interventions for children's physical and psychological health: a systematic review and meta-analysis

Psychological Medicine ◽

10.1017/s0033291719000692 ◽

2019 ◽

Vol 49 (11) ◽

pp. 1787-1798 ◽

Cited By ~ 1

Author(s):

Juan M. Flujas-Contreras ◽

Azucena García-Palacios ◽

Inmaculada Gómez

Keyword(s):

Systematic Review ◽

Psychological Health ◽

Psychological Intervention ◽

Meta Analysis ◽

Outcome Data ◽

Parenting Interventions ◽

Intervention Model ◽

Emotional Wellbeing ◽

Positive Effects ◽

Parents And Children

AbstractBackgroundParenting interventions have important consequences for the wellbeing and emotional competences of parents and their children. Technology provides an opportunity with advantages for psychological intervention. The aim of this systematic review and meta-analysis is to analyze the characteristics and effectiveness of technology-based interventions for parents to promote children's physical health or psychological issues.MethodsWe conducted a systematic review and meta-analysis for articles about parenting skills for prevention or treatment of children's physical or psychological concerns using technology. We explore the aim of the intervention with parents, kind of problem with children, intervention model, instruments, methodological quality, and risk of bias. A random-effects meta-analysis was conducted.ResultsTwenty-four studies were included in the systematic review and a meta-analysis of 22 studies was performed to find out the effects of intervention depending on the kind of problem, intervention model, follow-up, type of intervention, type of control condition, and type of outcome data. Results show the usefulness of technology-based therapy for parenting interventions with moderate effect sizes for intervention groups with statistically significant differences from control groups.ConclusionsTechnology-based parenting programs have positive effects on parenting and emotional wellbeing of parents and children. Attendance and participation level in technology-based treatment increase compared with traditional parenting intervention.

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