Ocular surface bacterial load in intravitreal injections: lid speculum vs. manually assisted retraction

2020 ◽  
Vol 29 (2) ◽  
pp. 123
Author(s):  
Selçuk SIZMAZ ◽  
Kibar FİLİZ ◽  
Esen EBRU ◽  
Demircan NİHAL
Keyword(s):  
Ocular Surface ◽  
Bacterial Load ◽  
Intravitreal Injections

Povidone-Iodine 3-Minute Exposure Time is Viable in Preparation for Cataract Surgery

2017 ◽  
Vol 27 (5) ◽  
pp. 573-576 ◽  
Author(s):  
Chu L. Nguyen ◽  
Lawrence J. Oh ◽  
Eugene Wong ◽  
Ian C. Francis
Keyword(s):  
Clinical Practice ◽  
Cataract Surgery ◽  
Exposure Time ◽  
Ocular Surface ◽  
Povidone Iodine ◽  
Bacterial Load ◽  
Minute Exposure ◽  
Visual Outcomes ◽  
Preoperative Prophylaxis ◽  
Operating Room Staff

Purpose Povidone-iodine (PI) is widely used to reduce the preoperative conjunctival bacterial load. This study aimed to evaluate the employment of PI 10% in an attempt to sterilize the ocular surface prior to cataract surgery, and to show that PI could be left in contact for 3 minutes. The viability of this exposure time in clinical practice, associated adverse events, and visual outcomes were documented. Methods In this prospective cohort study, phacoemulsification cataract surgery was performed in 604 patients by a single surgeon. Preoperative preparation was undertaken with PI 10%, applied to the cornea, conjunctival sac, eyelids, and periorbital skin with sterile cotton gauze. Povidone-iodine was then flushed onto the ocular surface. Operating room staff timed the precise duration of exposure. After the 3-minute preparation, the lids were thoroughly dried with fresh dry gauze. Results The median PI exposure time was 3.17 minutes, with an interquartile range of 0.25. All cases were followed up postoperatively at 1 day, 1 week, and 1 month. There were no complications attributable to PI. Visual outcomes were satisfactory. Conclusions Implementation of a preoperative prophylaxis protocol that used PI 10% with a 3-minute exposure time can be performed in clinical practice. The 3-minute exposure time had no adverse sequelae.

scholarly journals Effectiveness of 0.66% Povidone-Iodine Eye Drops on Ocular Surface Flora before Cataract Surgery: A Nationwide Microbiological Study

2021 ◽  
Vol 10 (10) ◽  
pp. 2198
Author(s):  
Rosario Musumeci ◽  
Pasquale Troiano ◽  
Marianna Martinelli ◽  
Matteo Piovella ◽  
Claudio Carbonara ◽  
...  
Keyword(s):  
Cataract Surgery ◽  
Ocular Surface ◽  
Povidone Iodine ◽  
Bacterial Species ◽  
Bacterial Flora ◽  
Bacterial Load ◽  
Controlled Study ◽  
Eye Drops ◽  
Microbiological Analysis ◽  
Contralateral Eye

A multicenter, nonrandomized, prospective, controlled study was conducted to evaluate, as perioperative prophylactic treatment, the anti-infective effectiveness of 0.66% povidone-iodine eye drops (IODIM®) against the bacterial flora of the conjunctival surface of patients who undergo cataract surgery. Eye drops containing 0.66% povidone-iodine were applied to the eye undergoing cataract surgery; the untreated contralateral eye was used as control. One hundred and twenty patients set to receive unilateral cataract surgery were enrolled in 5 Italian Ophthalmology Centers and pretreated for three days with 0.66% povidone-iodine eye drops. The contralateral eye, used as control, was left untreated. Conjunctival swabs of both eyes were collected at the baseline visit and after three days of treatment, just before the cataract surgery. A qualitative and quantitative microbiological analysis of bacterial presence was evaluated by means of bacterial culture, followed by identification. Methicillin resistance determination was also performed on staphylococci isolates. Bacterial load before and after treatment of the eye candidate for cataract surgery was evaluated and compared to the untreated eye. A reduction or no regrowth on the culture media of the bacterial load was observed in 100% of the study subjects. A great heterogenicity of bacterial species was found. The 0.66% povidone-iodine eye drops, used for three days prior to cataract surgery, were effective in reducing the conjunctival bacterial load. The 0.66% povidone-iodine eye drops (IODIM®) might represent a valid perioperative prophylactic antiseptic adjuvant treatment to protect the ocular surface from microbial contamination in preparation of the surgical procedure.

Ocular surface effects of repeated application of povidone iodine in patients receiving frequent intravitreal injections

2017 ◽  
Vol 36 (4) ◽  
pp. 343-346 ◽  
Author(s):  
Habiba Saedon ◽  
Jennifer Nosek ◽  
Julian Phillips ◽  
Nirodhini Narendran ◽  
Yit C. Yang
Keyword(s):  
Ocular Surface ◽  
Povidone Iodine ◽  
Surface Effects ◽  
Intravitreal Injections ◽  
Repeated Application

scholarly journals Identification of foreign bodies on the ocular surface after uneventful intravitreal injections

2012 ◽  
Vol 90 (8) ◽  
pp. e646-e647 ◽  
Author(s):  
Jesper S. Jørgensen ◽  
Henrik Kemp ◽  
Torben L. Sørensen
Keyword(s):  
Ocular Surface ◽  
Foreign Bodies ◽  
Intravitreal Injections

BACTERIAL CONTAMINATION OF OCULAR SURFACE AND NEEDLES IN PATIENTS UNDERGOING INTRAVITREAL INJECTIONS

Retina ◽  
2008 ◽  
Vol 28 (6) ◽  
pp. 877-883 ◽  
Author(s):  
JOHN J. DE CARO ◽  
CHRISTOPHER N. TA ◽  
HOAI-KY V. HO ◽  
LORELLA CABAEL ◽  
NAN HU ◽  
...  
Keyword(s):  
Ocular Surface ◽  
Bacterial Contamination ◽  
Intravitreal Injections

A prospective multicentre study of intravitreal injections and ocular surface in 219 patients: IVIS study

2021 ◽  
Author(s):  
Sarah Verrecchia ◽  
Fredéric Chiambaretta ◽  
Laurent Kodjikian ◽  
Yasemin Nakouri ◽  
Hussam El Chehab ◽  
...  
Keyword(s):  
Multicentre Study ◽  
Ocular Surface ◽  
Intravitreal Injections ◽  
Prospective Multicentre Study

Effects of perioperative managements on ocular surface microbiota in intravitreal injection patients

2021 ◽  
Author(s):  
Yaguang Hu ◽  
Qiong Wu ◽  
Fang Sui ◽  
Ming Zhang ◽  
Zhen Zhang ◽  
...  
Keyword(s):  
High Throughput ◽  
Ocular Surface ◽  
Beta Diversity ◽  
High Throughput Sequencing ◽  
Intravitreal Injections ◽  
Shaanxi Province ◽  
Eye Drops ◽  
Species Classification ◽  
Sequencing Platform ◽  
Significant Difference

Abstract Background: We investigated the effects of perioperative managements on ocular surface microbiota in patients who received intravitreal injections.Methods: Samples of ocular surface microbiota were obtained from 41 eyes of 41 patients who received intravitreal injections at the First Affiliated Hospital of Xi'an Jiaotong University and People’s Hospital in Shaanxi Province. The microbial 16s rDNA from samples were analyzed using an Illumina MiSeq high-throughput sequencing platform. Operating classification units (OTU) clustering and alpha/beta diversity analysis was performed for species classification.Results: High-throughput sequencing yielded 1697337 sequences and 1396, indicating an equivalent number of ocular surface microbiota. OTU was significantly lower in the eyes that received intravitreal injections, compared with those who did not received injections (P<0.05). The number of OTUs was inversely correlated with the administered of perioperative managements and the times of intravitreal injections. Beta diversity showed a significant difference among each groups (P<0.05). With the increased perioperative managements, the prevalence of gram-positive bacteria (Clostridium) had decreased and the prevalence of gram-negative bacteria (Neisseria) had increased.Conclusions: Microbiota on the ocular surface were significantly different between treated and control eyes. And the composition of microbiota on the ocular surface was dramatically changed over time in eyes that received intravitreal injections. Perioperative managements might disrupt the balance of the ocular surface microbiota, increasing risk of infectious disease. Therefore, perioperative managements including local antibiotic eye drops should be applied cautiously before intraocular surgery.

Sign in / Sign up

Export Citation Format

Share Document