Evaluation of Hepatitis B & Hepatitis C Virus co-infection among the hemodialysis patients in Lucknow, Uttar Pradesh, India

2015 ◽  
Vol 4 (6) ◽  
pp. 323-326
Author(s):  
Shantanu Prakash ◽  
S. N. Sankhwar ◽  
Amita Jain ◽  
Kausar Usman ◽  
Narayan Prasad ◽  
...  

  Hepatitis B virus (HBV) and hepatitis C virus (HCV) infection substantially cause series of liver diseases worldwide. Because these two viruses share the modes of transmission, HBV HCV co-infection is common with approximately 7-20 million people affected globally. Hemodialysis individuals are at risk of HBV and HCV infections. The prevalence rates of coinfection with HBV and HCV in Hemodialysis patients have been variable worldwide depending on the geographic regions, and the type of exposure. This study aimed to exam-ine HBV and HCV coinfection and determine the shared and significant fac-tors in the coinfection in Hemodialysis patients. This descriptive, cross-sectional study was carried out on 237 Hemodialysis patients including 153 males and 84 females in Lucknow, Uttar Pradesh, to survey coinfection with HBV and HCV using ELISA. The retrospective demographic data of the sub-jects was collected and the patient’s serums were analyzed by ELISA. The collected data was analyzed with Instat (Graphpad) software. Fisher's exact test with 5% error intervals was used to measure the correlation of variables and infection rates. The results of the study indicated that the prevalence of hepatitis B & C virus in hemodialysis patients was 9.70% (n=23), out of which 1 (0.42%) was suffering with HBV & HCV co-infection while 6 were only HBV positive and 16 were only HCV positive. There is very low prevalence of Hep-atitis C Virus and Hepatitis B Virus coinfection in hemodialysis patients in this region.

2019 ◽  
Vol 2019 ◽  
pp. 1-3
Author(s):  
Ahmed A. Dahab ◽  
Maha Mohamed Youssef ◽  
Hany Mohamed Eid ◽  
Khaled W. Elsadi

Introduction. Hepatitis B virus (HBV) and hepatitis C virus (HCV) and their long-term sequelae are considered a major health issue in Egypt. The aim of this study is to determine the prevalence of undiagnosed hepatitis B virus (HBV) and hepatitis C virus (HCV) among patients admitted for elective eye surgery in a specialized eye hospital in Cairo, Egypt. Materials and Methods. This cross-sectional study was conducted in a specialized eye hospital, Cairo, Egypt. The study included consecutive patients admitted for elective eye surgery in the period from April 2015 to June 2016. Age, sex, and procedure done were recorded for all patients. All the subjects were screened for HBV and HCV by rapid chromatography immunoassay; if positive, the results had to be confirmed by ELISA. Results. 3067 patients admitted for elective eye surgery were included in the study. The mean age of the patients was 50.85 ± 19.77 years. There were 1592 (51.9%) males and 1475 (48.1%) females. The prevalence of preoperative positive HBV and HCV was 7/3067 (0.2%) and 381/3067 (12.4%), respectively. Conclusion. Given the high prevalence of HBV and HCV infection in our population in general and in this study specifically, all patients admitted for surgery should be screened for both viruses.


2020 ◽  
Author(s):  
Semvua Kilonzo ◽  
Daniel W. Gunda ◽  
David C. Majinge ◽  
Hyasinta Jaka ◽  
Paulina M. Manyiri ◽  
...  

Abstract Background: Methadone therapy clinics have been recently introduced in Tanzania, aiming at reducing risk behaviors and infection rates of viral hepatitis and HIV among people who use drugs. The objective of this study was to estimate the prevalence, associated factors and knowledge level of these conditions among people who use drugs attending a methadone clinic in Tanzania.Methods: We enrolled 253 People who using drugs receiving Methadone therapy. Clinical data was retrospectively collected from the medical records and face-to face interviews were conducted to determine the behavioral risk factors and respondents’ knowledge on viral hepatitis and HIV.Results: An overall seroprevalence of viral hepatitis (either hepatitis B surface antigen or anti-hepatitis C virus) was 6.3%, while that of hepatitis B virus mono infection was 3.5% and anti-hepatitis C virus mono infection was 3.5%. Seroprevalence of HIV was 12.6%. Viral hepatitis was strongly predicted by advanced age (>35 years) (p=0.02) and staying at Kirumba area (p=0.004), and HIV infection was predicted by increased age (>37 years) (p=0.04) and female sex (p<0.001). Regarding the knowledge of viral hepatitis, majority of the respondents were unaware of the transmission methods and availability of hepatitis B virus vaccines and only 17% were classified as well informed (provided ≥ 4 correct answers out of 7 questions). Good knowledge was highly predicted by higher education level of the individual (p=0.001).Conclusions: Despite the efforts to curb viral hepatitis and HIV infections through Methadone clinics, infection rates among people who use drugs are still high and the general knowledge on preventive measures is inadequate.


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