scholarly journals THE BACTERIAL CHROMOSOMAL SEQUENCE AND RELATED ISSUES

2013 ◽  
Vol 2 (1) ◽  
pp. 1-7 ◽  
Author(s):  
Phan
Keyword(s):  
Chromosomal Sequence

scholarly journals Evolutionary characterization of a Y chromosomal sequence conserved in the genus Mus

1988 ◽  
Vol 52 (2) ◽  
pp. 145-150 ◽  
Author(s):  
Yutaka Nishioka
Keyword(s):  
Related Species ◽  
Rattus Norvegicus ◽  
Phylogenetic Relationships ◽  
Repetitive Sequence ◽  
Repetitive Sequences ◽  
Closely Related Species ◽  
Specific Hybridization ◽  
Male Specific ◽  
Chromosomal Sequence

SummaryThe extent of accumulation of mouse Y chromosomal repetitive sequences generally correlates with the known phylogenetic relationships in the genus Mus. However, we describe here a M. musculus Y chromosomal repetitive sequence, designated as ACClfl, whose accumulation patterns among eight Mus species do not correspond to their phylogenetic relationships. Although male-specific hybridization bands were present in all the species examined, significant accumulation (> 200 copies) in the Y chromosomes was found in M. minutoides (subgenus Nannomys), M. pahari (subgenus Coelomys) and M. saxicola (subgenus Pyromys) as well as in the three closely related species M. hortulanus, M. musculus and M. spretus that belong to the subgenus Mus. Unexpectedly, the Y chromosomes of M. caroli and M. cookii (both subgenus Mus) had considerably reduced amounts of ACClfl-related sequences. Furthermore, in rats (Rattus norvegicus) the major accumulation sites appear to be autosomal. These observations suggest that caution must be taken in the interpretation of data obtained with repetitive sequences that have evolved quickly.

scholarly journals Complete Genome Sequence of GD1696, a Low-Virulence Strain of Human-Associated ST398 Methicillin-Susceptible Staphylococcus aureus

2019 ◽  
Vol 8 (28) ◽  
Author(s):  
Jo-Ann McClure ◽  
Steven M. Shideler ◽  
Kunyan Zhang
Keyword(s):  
Staphylococcus Aureus ◽  
Genome Sequence ◽  
Complete Genome Sequence ◽  
Complete Genome ◽  
Sequence Type ◽  
Content Type ◽  
Mssa Strain ◽  
Chromosomal Sequence

The emerging livestock-associated Staphylococcus aureus multilocus sequence type 398 (ST398) appears to have augmented virulence in humans. However, it is unclear if all ST398 strains are equally virulent. Here, we present the chromosomal sequence of a low-virulence ST398 methicillin-susceptible S. aureus (MSSA) strain, GD1696, to investigate ST398 sublineage virulence.

scholarly journals Gexplora – user interface that highlights and explores the density of genomic elements along a chromosomal sequence

2020 ◽  
Author(s):  
Thomas Nussbaumer ◽  
Olivia Debnath ◽  
Parviz Heidari
Keyword(s):  
User Interface ◽  
Transposable Elements ◽  
Detailed Analysis ◽  
Candidate Genes ◽  
Graphical User Interface ◽  
Genomic Sequence ◽  
A Genome ◽  
Rest Api ◽  
Protein Datasets ◽  
Chromosomal Sequence

AbstractThe density of genomic elements such as genes or transposable elements along its consecutive sequence can provide an overview of a genomic sequence while in the detailed analysis of candidate genes it may depict enriched chromosomal hotspots harbouring genes that explain a certain trait. The herein presented python-based graphical user interface Gexplora allows to obtain more information about a genome by considering sequence-intrinsic information from external databases such as Ensembl, OMA and STRING database using REST API calls to retrieve sequence-intrinsic information, protein-protein datasets and orthologous groups. Gexplora is available under https://github.com/nthomasCUBE/Gexplora.

Xenopus Hox-2 genes are expressed sequentially after the onset of gastrulation and are differentially inducible by retinoic acid

Development ◽  
1992 ◽  
Vol 116 (Supplement) ◽  
pp. 195-202 ◽  
Author(s):  
Erik-Jan Dekker ◽  
Maria Pannese ◽  
Erwin Houtzager ◽  
Ans Timmermans ◽  
Edoardo Boncinelli ◽  
...  
Keyword(s):  
Retinoic Acid ◽  
Expression Patterns ◽  
Positional Information ◽  
Developmental Expression ◽  
Temporal Expression ◽  
Mammalian Cell Lines ◽  
All Trans Retinoic Acid ◽  
Temporal Expression Pattern ◽  
Six Genes ◽  
Chromosomal Sequence

In this paper, we review experiments to characterise the developmental expression and the responses to all-trans retinoic acid (RA) of six members of the Hox-2 complex of homeobox-containing genes, during the early development of Xenopus laevis. We showed that the six genes are expressed in a spatial sequence which is colinear with their putative 3′ to 5′ chromosomal sequence and that five of them are also expressed rapidly after the beginning of gastrulation, in a 3′ to 5′ colinear temporal sequence. The sixth gene (Xhox2.9) has an exceptional spatial and temporal expression pattern. The six genes all respond to RA by showing altered spatiotemporal expression patterns, and are also RA-inducible, the sequence of the magnitudes of their RA responses being colinear with their 3′ to 5′ chromosomal sequence, and with their spatial and temporal expression sequences. Our data also reveal that there is a pre-existing anteroposterior polarity in the embryo's competence for a response to RA. These results complement and extend previous findings made using murine and avian embryos and mammalian cell lines. They suggest that an endogenous retinoid could contribute to positional information in the early Xenopus embryo.

scholarly journals Inverted duplication-transposition event in mammalian cells at an illegitimate recombination join.

1986 ◽  
Vol 6 (6) ◽  
pp. 2179-2184 ◽  
Author(s):  
T J Williams ◽  
M Fried
Keyword(s):  
Mammalian Cells ◽  
Recombination Event ◽  
Single Copy ◽  
Illegitimate Recombination ◽  
Viral Integration ◽  
Base Pairs ◽  
Viral Dna ◽  
Transformed Cell Line ◽  
Inverted Duplication ◽  
Chromosomal Sequence

Illegitimate recombination events in mammalian cells often contain extraneous nucleotides or filler DNA at the recombinant joins. The polyomavirus-transformed cell line 7axB has previously been found to contain 37 base pairs (bp) of filler DNA at one virus-host join of the single insert of integrated viral DNA (A. Hayday, H. E. Ruley, and M. Fried, J. Virol. 44:67-77, 1982). By using a synthetic oligomer of these 37 bp as a probe, we demonstrated that this filler DNA is an inverted duplication of a single-copy rat sequence found 650 bp upstream from this virus-host join. The other virus-host join appears to be the result of a simple illegitimate recombination event between viral and host sequences. This is the first identification of filler DNA as a transposed copy of a chromosomal sequence. The relevance of the recombination events studied to cellular rearrangements and viral integration is discussed.

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