scholarly journals Hyperpigmented Nodular Dermatofibroma: Two Cases Report and Brief Literature Review

2021 ◽  
Vol 9 (C) ◽  
pp. 198-203
Author(s):  
Andi Hardianty ◽  
Khairuddin Djawad ◽  
Siswanto Wahab ◽  
Airin Nurdin

BACKGROUND: Dermatofibroma (DF) is a common benign skin tumor (Benign Fibrous Histiocytoma) that mostly affects the extremities with a tendency to occur more often in older females than males. It usually presents as a slow growing small brown dome shape papule on the extremities. DF has a chronic nature and can sometimes regresses spontaneously. Dermoscopy is essential in the evaluation of DF to help differentiate it with other skin tumors. The gold standard evaluation for diagnosis of DF is biopsy with histopathologic examination. Removal of DF is often due to cosmetic factors, with surgical excision being the preferred method for removal. DF has an excellent prognosis. CASE REPORT: We present two case reports of women with hyperpigmented nodules on the lower extremity. Dimple sign was positive. From dermoscopic study showed a pigment network and central white patch pattern. On histologic examination revealed proliferation of fibroblast such as spindle cells as a storiform pattern and hyperplastic epidermis with hyperpigmentation of the basal layer. Based on clinical features, dermoscopy and histopathological evaluation, the diagnosis of DF was established. Both patients were perform surgically excision and have a good result. CONCLUSION: Dermatofibroma is benign fibrous histiocytoma that represents one of the most common skin tumours. Nodular hyperpigmented dermatofibroma is a clinical variant of Dermatofibroma which can be treated with surgical excision with good prognosis.

2021 ◽  
pp. 1304-1309
Author(s):  
Mohammad Sharifi ◽  
Bahar Tafaghodi Yousefi

Benign fibrous histiocytoma of the para nasal sinus is a rare tumor of this region which originates from mesenchymal cells. A 9-year-old girl presented with gradually enlarging mass above the medial canthus over 3 months. Orbital computerized tomography scan showed a round well-differentiated homogeneous mass in the anterior ethmoidal sinus. Histology and immunohistochemistry analysis after excision revealed proliferation of spindle-shaped fibroblasts in storiform pattern and histiocytes without mitosis and anaplasia. After 9 months from surgical excision, recurrence occurred which resulted in total excision again. This is the first reported case of benign fibrous histiocytoma involving the ethmoid sinus in Iranian people. Rare sinus tumor should be considered in the differential diagnosis of sinus tumors.


Cases Journal ◽  
2009 ◽  
Vol 2 (1) ◽  
pp. 9343 ◽  
Author(s):  
Dardo Menditti ◽  
Luigi Laino ◽  
Antonio Mezzogiorno ◽  
Sara Sava ◽  
Alexander Bianchi ◽  
...  

2021 ◽  
Vol 9 (3) ◽  
pp. 339-344
Author(s):  
Hicham Abdellaoui ◽  
Mohammed Tazi Charqui ◽  
Fatoumata Binta Balde ◽  
Karima Atarraf ◽  
Afifi My Abderrahmane

BACKGROUND: Benign fibrous histiocytoma is known to be a frequent skin tumor but its occurrence in bone remains very rare especially in pediatric population. This entity is a subject of interest also because histologically it can mimic other fibrohistiocytic lesions of bone such as non-ossifying fibroma. CLINICAL CASE: An 11-year-old patient admitted with swelling of the right thigh and intermittent pain. Radiological evaluation shows cystic lesion of the femur with a soap-bubble and a border of condensation. Histopathological examination of the biopsy sample established the diagnosis of benign fibrous histiocytoma. The patient underwent complete curettage of the lesion with bone graft. There is no recurrence 16 months after surgery. DISCUSSION: Benign fibrous histiocytoma is a rare bone tumor especially in children. Histologically it can mimic non-ossifying fibroma. Thus clinical and radiological features are important to differentiate these tumors in order to choose adequate treatment. CONCLUSIONS: Benign fibrous histiocytoma is probably underestimated in pediatric population. This diagnosis should be considered in any child or teenager who presents with a non-ossifying fibroma accompanied by unexplainable pain or a rapid growing.


2016 ◽  
Vol 8 (3) ◽  
pp. 116-118
Author(s):  
Atishkumar B Gujrathi ◽  
Vijayalaxmi Ambulgekar ◽  
Shrinivas Chavan

ABSTRACT Vagal nerve schwannomas are rare neural sheath tumors. Although schwannomas are generally benign lesions, they are known to enlarge at a rate of 2.5 to 3 mm per year according to published reports. Vagal nerve schwannoma usually occurs between the 3rd and 5th decades of life, it does not show sex predilection, with both sexes being equally affected, and it most often presents as a painless, slow-growing, lateral neck mass. The treatment of choice is complete surgical excision with preservation of the neural pathway, when it is possible. These tumors, in fact, are almost always benign, and a conservative surgical approach is emphasized by most of the authors. Here, we are presenting two cases of cervical vagal schwannoma, both were middle aged females and presenting in the ear, nose, and throat (ENT) department as a painless lateral neck swelling and were operated by horizontal skin crease incision. Of the two cases, we succeeded to secure nerve functions in one case. The clinical features, diagnosis, management, and pathological findings of cervical vagal schwannoma are discussed. How to cite this article Gujrathi AB, Ambulgekar V, Chavan S. Vagal Nerve Schwannoma: Presentation of Two Case Reports. Int J Otorhinolaryngol Clin 2016;8(3):116-118.


Author(s):  
J. R. Galagali ◽  
I. D. Singh ◽  
Satish Kumar ◽  
Arvind Kumar Gupta

Glomus tumors, also known as paragangliomas and chemodectomas, of head and neck are slow growing benign tumors with relatively good prognosis. The term Glomus is misnomer as it arises from paraganglions. Due to their critical location at the skull base, these tumors may have significant morbidity and mortality if not identified and managed in time. The common extra adrenal sites in head and neck are carotid body, jugular foramen, middle ear and the vagus nerve. The term glomus jugulotympanicum is used when the tumor crosses the distinction of being confined either to middle ear or the jugular foramen. Management aims at early detection and complete surgical excision preserving surrounding vital neurovascular structures as far as possible. Larger tumors in advanced stage may not be amenable to complete surgical excision.


2020 ◽  
pp. 86-87
Author(s):  
G.konda reddy ◽  
Sowda pavani lakshmi ◽  
Y. Narendra ◽  
Pradeep. K ◽  
C.Mahesh kumar Raju

Benign fibrous histiocytomas are common soft tissue tumours located anywhere in the body but most commonly found in skin. These are slow growing tumours common in all races and all ages but most common age group is 20 to 49 years with female preponderance. In our case a 27-year-old female with complaints of abdominal pain underwent an ultrasound abdomen and pelvis in which a retroperitoneal tumour was diagnosed. Except for abdominal pain no other complaints were noted she was well preserved. we have done an exploratory laparotomy with excision of tumour and specimen sent for Histopathological examination in which it is confirmed as benign fibrous histiocytoma. Post-operative period uneventful and she recovered well. It is rare site for the occurrence of the histiocytoma.


2019 ◽  
Vol 88 (6) ◽  
pp. 320-326 ◽  
Author(s):  
Z. Joostens ◽  
L. Vanslambrouck ◽  
H. De Cock ◽  
T. Mariën

A six-year-old warmblood horse was presented with a longstanding frontlimb lameness with mild digital flexor tenosynovitis and swelling of the distomedial pastern. Ultrasonography and magnetic resonance revealed a dense mass lesion in the distal aspect of the digital flexor tendon sheath, with a partial lamellar architecture, absence of internal vascularization and adjacent smooth pressure osteolysis of the middle phalanx. After surgical excision, histopathology confirmed an epithelial inclusion cyst. Epithelial inclusion cysts, also known as keratinizing or follicular cysts, are expansile benign mass-like lesions of aberrant epidermal tissue. In the horse, they are known to occur in cutaneous and several non-cutaneous tissues. In the digital flexor tendon sheath, they have rarely been described. Given their often chronic presentation in this location, they may appear as an atypical dense mass on imaging, uncommon for cystic lesions. Complete tenoscopic removal, even for larger masses, is achievable and considered curative with good prognosis for return.


2021 ◽  
Vol 15 (1) ◽  
Author(s):  
Afsaneh Tehranian ◽  
Akram Ghahghaei-Nezamabadi ◽  
Akram Seifollahi ◽  
Sara Kasraei ◽  
Hamideh Dehghani-Nejad ◽  
...  

Abstract Background Mature Cystic Teratoma (MCT) is a benign tumor that can lead to malignant transformation (MT) in 1–3% of cases. Management of MT is a big challenge for gynecologic oncologists due to the lack of specific diagnostic and treatment protocols. Case presentation We reported two Iranian cases of MT of MCT with two different stages and prognosis. Our both cases presented the same symptoms, including chronic abdominal pain and distention, loss of appetite, and weight loss. In case number 1, despite the large size of the tumor, the disease was at stage Ia and had a good prognosis; while, case number 2 was at stage IIIc of the disease with a poor prognosis. Conclusion The stage of the disease is the most important prognostic factor, and early diagnosis and treatment are very critical for better survival.


2021 ◽  
Vol 49 (01) ◽  
pp. 046-055
Author(s):  
Victoria Hernández ◽  
Tania Lena ◽  
Eliana Camacho ◽  
Matías Craviotto

AbstractGlomus tumors are a mostly benign neoplasm that constitutes less than 4% of upper-limb soft-tissue tumors. Its unspecific clinical presentation, added to its low frequency, leads to a late diagnosis.The objective of the present study is to update the clinical-paraclinical approach and the surgical technique used in the treatment.We carried out a literature review from 2014 to 2019 on digital glomus tumor in the hand in adult patients using the PubMed search engine.In most of the publications analyzed, the diagnosis was clinical, with a delay of 1 to 10 years. Plain radiography is the most requested study; of the 16 articles reporting its indication, only half evidenced compatible changes. Magnetic resonance imaging (MRI) was requested in 15 articles, presenting normal results in 3 of them. The treatment of choice was surgical excision using a transungual approach. Only 4 articles report recurrence after excision.Although there is diversity in the approach to these tumors, we conclude that the diagnosis is clinical, and the treatment surgical, and there is no consensus regarding the paraclinical indication. The information available comes mainly from case reports, publications that contribute to the generation of evidence for the clinical practice in rare diseases such as this one.


2021 ◽  
pp. 106689692110011
Author(s):  
Neha Bakshi ◽  
Shashi Dhawan ◽  
Seema Rao ◽  
Kishan Singh Rawat

Introduction. Micronodular thymoma with lymphoid stroma (MNTLS) is a rare thymoma subtype characterized by distinctive histological appearance, unique clinical profile, and indolent course with good prognosis. In addition to its distinctive morphology, MNTLS may be associated with diverse histological features, such as thymic cysts and conventional thymoma, complicating the diagnostic picture further. Materials and methods. We report herein an account of 3 elderly patients (male—02; female—01), who presented with anterior mediastinal mass, and underwent robotic thymectomy. Microscopic examination revealed MNTLS in all 3 cases. In addition, 2 cases showed associated histological features in the form of a multilocular thymic cyst and conventional (type B2) thymoma, respectively. All 3 patients are doing well without recurrence or metastasis at 34, 28, and 19 months postsurgery. Conclusions. Awareness of this rare thymoma subtype is vital among pathologists to avoid misdiagnosis and ensure appropriate patient management. To date, only a few cases of this rare thymoma subtype have been reported in the literature, mostly as single case reports.


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