scholarly journals Hereditary protein S deficiency leads to ischemic stroke

2015 ◽  
Vol 12 (3) ◽  
pp. 3279-3284 ◽  
Author(s):  
ZHAO-HUI WANG ◽  
ZHI-JUN ZHAO ◽  
KANG XU ◽  
GUO-BING SUN ◽  
LIN SONG ◽  
...  
1970 ◽  
Vol 13 (1) ◽  
pp. 100-102
Author(s):  
Aparna Das ◽  
AKM Aminul Hoque ◽  
Ratan Dasgupta ◽  
Ahmedul Kabir ◽  
Gobinda Banik ◽  
...  

A 50- year-old female was presented with recurrent venous thrombosis with ischemic stroke due to protein S deficiency. Other causes of recurrent venous thrombosis were excluded by different investigations. We only found low level of protein S. In most of the cases, thrombophilia screening is not usaally done. So, this report will illustrate the importance of thrombophlia screening in patient having recurrent venous thrombosis. DOI: http://dx.doi.org/10.3329/jom.v13i1.10085 JOM 2012; 13(1): 100-102


Stroke ◽  
1993 ◽  
Vol 24 (2) ◽  
pp. 224-227 ◽  
Author(s):  
S A Mayer ◽  
R L Sacco ◽  
A Hurlet-Jensen ◽  
T Shi ◽  
J P Mohr

2016 ◽  
Vol 15 (4) ◽  
pp. 187-191
Author(s):  
Diana Matcau ◽  
◽  
Claudia Barsan ◽  
Traian Flavius Dan ◽  
Camelia Barbusi ◽  
...  

Thrombophilia is characterized by an increased tendency to arterial and venous thrombus formation. Inherited thrombophilia can be secondary to protein S deficiency. Concomitant use of oral contraceptive pills increases the risk of venous thromboembolism and arterial thrombosis. We report a case of a 34-year-old female who used oral contraceptive pills for many years, who developed acute ischemic stroke of right occipital lobe with secondary left superior homonymous quadrantanopia. We have run several tests to establish the ischemic stroke etiology: unenhanced brain and cervical spine computed tomography, brain magnetic resonance imaging and magnetic resonance angiography (including MR venography), computed tomographic angiography, echocardiography, extracranial duplex ultrasound and laboratory data (including thrombophilia testing). The laboratory investigations confirmed that the ischemic stroke of our patient resulted from a severe inherited thrombophilia secondary to protein S deficiency.


2013 ◽  
Vol 28 (1) ◽  
pp. 59-62
Author(s):  
Hasan Zahidur Rahman ◽  
Sharif Uddin Ahmed ◽  
Mohammad Najim Uddin ◽  
Masud Rana ◽  
Anis Ahmed ◽  
...  

Stroke is the third most common cause of mortality in Westernised countries and Accounts for 12% of all deaths in the UK. The economic cost of stroke is enormous. Twelve per cent of first strokes occur in patients under 45 years of age, of which approximately 50% are ischaemic in nature. Stroke in young adult poses a major health problem. The causes of ischaemic stroke in young adults are many and diverse.Such patients usually require more extensive investigations in order to find an underlying cause than more elderly patients. Principal causes are cardioembolism, premature atherosclerosis, haematological and immunological disorders and migraine. Thrombophilic factors have been implicated in 4-8% of the young adult strokes worldwide. Protein S deficiency is a rare cause of ischemic stroke in young population. Only a few sporadic cases have been described in the literature. We are reporting a case of protein S deficiencyrelated ischemic stroke in a 40-year-old man. Early diagnosis and targeted approach can help such patients to prevent recurrent thrombotic episodes.Bangladesh Journal of Neuroscience 2012; Vol. 28 (1): 59-62


Author(s):  
Ikkei Ohashi ◽  
Shinichi Wada ◽  
Fumitaka Yoshino ◽  
Takahiro Kuwashiro ◽  
Shinya Matsumoto ◽  
...  

2009 ◽  
Vol 12 (3) ◽  
pp. 183 ◽  
Author(s):  
Amit Hooda ◽  
PD Khandelwal ◽  
Puneet Saxena

2018 ◽  
Vol 5 (2) ◽  
pp. 345-356
Author(s):  
Juan David Vega Padilla ◽  
Juan David Vivas Suarez ◽  
Jorge Andrés Sánchez Jiménez ◽  
Viviana Carolina Vargas Quintana

A 19-year-old woman with a 6-year history, consisting of frequent falls and weakness due to loss of strength in the lower extremities. During the last 10 hours, she presented a sudden episode of left hemiplegia, deviation of the labial commissure to the right, dysarthria and four emetic episodes. She was diagnosed with an ischemic stroke caused by a deficiency of the S-protein and, in addition, a muscular dystrophy. This case report may indicate a relationship between muscular dystrophy and ischemic stroke caused by a protein S deficiency


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