Matrine induces apoptosis in acute myeloid leukemia cells by inhibiting the PI3K/Akt/mTOR signaling pathway

Oncology Letters ◽

10.3892/ol.2019.10649 ◽

2019 ◽

Author(s):

Yanmei Hao ◽

Nan Zhang ◽

Nannan Wei ◽

Hongmei Yin ◽

Yingjie Zhang ◽

...

Keyword(s):

Acute Myeloid Leukemia ◽

Signaling Pathway ◽

Myeloid Leukemia ◽

Mtor Signaling ◽

Leukemia Cells ◽

Mtor Signaling Pathway ◽

Acute Myeloid Leukemia Cells ◽

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LukS-PV induces differentiation by activating the ERK signaling pathway and c-JUN/c-FOS in human acute myeloid leukemia cells

The International Journal of Biochemistry & Cell Biology ◽

10.1016/j.biocel.2016.04.005 ◽

2016 ◽

Vol 76 ◽

pp. 107-114 ◽

Author(s):

Chunyang Dai ◽

Chengfang Zhang ◽

Xiaoxi Sun ◽

Qing Pan ◽

Jing Peng ◽

...

Keyword(s):

Acute Myeloid Leukemia ◽

Signaling Pathway ◽

Myeloid Leukemia ◽

Erk Signaling ◽

Leukemia Cells ◽

Human Acute Myeloid Leukemia ◽

Acute Myeloid Leukemia Cells ◽

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mTOR signaling is activated by FLT3 kinase and promotes survival of FLT3-mutated acute myeloid leukemia cells

Molecular Cancer ◽

10.1186/1476-4598-9-292 ◽

2010 ◽

Vol 9 (1) ◽

pp. 292 ◽

Author(s):

Weina Chen ◽

Elias Drakos ◽

Ioannis Grammatikakis ◽

Ellen J Schlette ◽

Jiang Li ◽

...

Keyword(s):

Acute Myeloid Leukemia ◽

Myeloid Leukemia ◽

Mtor Signaling ◽

Leukemia Cells ◽

Acute Myeloid Leukemia Cells ◽

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Induction of Multidrug Resistance of Acute Myeloid Leukemia Cells by Cocultured Stromal Cells via Upregulation of the PI3K/Akt Signaling Pathway

Oncology Research Featuring Preclinical and Clinical Cancer Therapeutics ◽

10.3727/096504016x14634208143021 ◽

2016 ◽

Vol 24 (4) ◽

pp. 215-223 ◽

Author(s):

Ping Chen ◽

Qing Jin ◽

Qiang Fu ◽

Peidong You ◽

Xi Jiang ◽

...

Keyword(s):

Acute Myeloid Leukemia ◽

Multidrug Resistance ◽

Signaling Pathway ◽

Stromal Cells ◽

Myeloid Leukemia ◽

Akt Signaling ◽

Leukemia Cells ◽

Akt Signaling Pathway ◽

Acute Myeloid Leukemia Cells ◽

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Saponins From Paris forrestii (Takht.) H. Li Display Potent Activity Against Acute Myeloid Leukemia by Suppressing the RNF6/AKT/mTOR Signaling Pathway

Frontiers in Pharmacology ◽

10.3389/fphar.2018.00673 ◽

2018 ◽

Vol 9 ◽

Author(s):

Qin Lu ◽

Yuanming He ◽

Yuehu Wang ◽

Li Gao ◽

Yunjing Zheng ◽

...

Keyword(s):

Acute Myeloid Leukemia ◽

Signaling Pathway ◽

Myeloid Leukemia ◽

Mtor Signaling ◽

Mtor Signaling Pathway ◽

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Overexpression of microRNA-125b inhibits human acute myeloid leukemia cells invasion, proliferation and promotes cells apoptosis by targeting NF-κB signaling pathway

Biochemical and Biophysical Research Communications ◽

10.1016/j.bbrc.2017.05.007 ◽

2017 ◽

Vol 488 (1) ◽

pp. 60-66 ◽

Author(s):

Yan Wang ◽

Ping Tang ◽

Yanli Chen ◽

Jingyu Chen ◽

Ruojin Ma ◽

...

Keyword(s):

Acute Myeloid Leukemia ◽

Signaling Pathway ◽

Myeloid Leukemia ◽

Leukemia Cells ◽

Human Acute Myeloid Leukemia ◽

Acute Myeloid Leukemia Cells ◽

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MicroRNA-9 restrains the sharp increase and boost apoptosis of human acute myeloid leukemia cells by adjusting the Hippo/YAP signaling pathway

Bioengineered ◽

10.1080/21655979.2021.1915727 ◽

2021 ◽

Vol 12 (1) ◽

pp. 2906-2914

Author(s):

Guoqing Wang ◽

Xiuwen Yu ◽

Jiajia Xia ◽

Jie Sun ◽

Haiyan Huang ◽

...

Keyword(s):

Acute Myeloid Leukemia ◽

Signaling Pathway ◽

Sharp Increase ◽

Myeloid Leukemia ◽

Leukemia Cells ◽

Human Acute Myeloid Leukemia ◽

Acute Myeloid Leukemia Cells ◽

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Reactive oxygen species activate differentiation gene transcription of acute myeloid leukemia cells via the JNK/c-JUN signaling pathway

Leukemia Research ◽

10.1016/j.leukres.2018.03.012 ◽

2018 ◽

Vol 68 ◽

pp. 112-119 ◽

Author(s):

Chung Fan Lam ◽

Hoi Ting Yeung ◽

Yuk Man Lam ◽

Ray Kit Ng

Keyword(s):

Reactive Oxygen Species ◽

Acute Myeloid Leukemia ◽

Signaling Pathway ◽

Gene Transcription ◽

Myeloid Leukemia ◽

Leukemia Cells ◽

Oxygen Species ◽

Acute Myeloid Leukemia Cells ◽

Differentiation Gene ◽

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CD82 supports survival of childhood acute myeloid leukemia cells via activation of Wnt/β-catenin signaling pathway

Pediatric Research ◽

10.1038/s41390-019-0370-3 ◽

2019 ◽

Vol 85 (7) ◽

pp. 1024-1031 ◽

Author(s):

Hongyan Ji ◽

Li Chen ◽

Yuqian Xing ◽

Shanshan Li ◽

Jianjian Dai ◽

...

Keyword(s):

Acute Myeloid Leukemia ◽

Signaling Pathway ◽

Myeloid Leukemia ◽

Leukemia Cells ◽

Childhood Acute Myeloid Leukemia ◽

Acute Myeloid Leukemia Cells ◽

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DIXDC1 promotes the growth of acute myeloid leukemia cells by upregulating the Wnt/β-catenin signaling pathway

Biomedicine & Pharmacotherapy ◽

10.1016/j.biopha.2018.08.144 ◽

2018 ◽

Vol 107 ◽

pp. 1548-1555 ◽

Author(s):

Hong Xin ◽

Chengliang Li ◽

Minjuan Wang

Keyword(s):

Acute Myeloid Leukemia ◽

Signaling Pathway ◽

Myeloid Leukemia ◽

Leukemia Cells ◽

Acute Myeloid Leukemia Cells ◽

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Vibsanol A induces differentiation of acute myeloid leukemia cells via activation of the PKC signaling pathway and induction of ROS

Leukemia & Lymphoma ◽

10.1080/10428194.2017.1421754 ◽

2018 ◽

Vol 59 (10) ◽

pp. 2414-2422 ◽

Author(s):

Meng Yang ◽

Shuang Xing ◽

Hong-Ling Ou ◽

Lu Zhang ◽

Xing Shen ◽

...

Keyword(s):

Acute Myeloid Leukemia ◽

Signaling Pathway ◽

Myeloid Leukemia ◽

Leukemia Cells ◽

Pkc Signaling ◽

Acute Myeloid Leukemia Cells ◽

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