Construct validity of The Routine Assessment of Patient Index Data 3 (RAPID3) in the evaluation of axial spondyloarthritis

Objective Although there are different tools to evaluate axial spondyloarthritis (axSpA), they are hardly used in clinical routine due to time constraints. The Routine Assessment of Patient Index Data 3 (RAPID3) is a composite measure feasible to be used as a sole metric in busy clinics. We aimed to test its measurement properties in patients with axial SpA in a real clinical setting. Methods Cross-sectional study that included 131 consecutive patients with axial SpA. The convergent (Spearman's rho) and discriminant (ROC curve analysis) validity of RAPID3 were tested against several axSpA-specific measures (BASDAI, ASDAS, BASFI, mSASSS). A multivariate model was built to detect disease factors associated with RAPID3 remission (values ≤3). Results The study included 82 men and 49 women, median age of 55 years (IQR: 46-61), and median disease duration of 11 years (IQR: 6-24). Mean RAPID3 was 9.45 ± 6.7. The BASDAI showed moderate correlation with ASDAS (rho: 0.66, p < 0.0001), but higher with BASFI (rho: 0.78, p < 0.0001) and RAPID3 (rho: 0.75, p < 0.0001). The ASDAS had moderate correlations with BASFI, BASDAI, and RAPID3 (ranges from 0.66 to 0.68, p < 0.0001). Higher correlations were found between BASFI and BASDAI (rho: 0.78, p < 0.0001) and BASFI-RAPID3 (rho: 0.73, p < 0.0001). The m-SASSS did not show any correlation with any of the afore-mentioned composite measures. Kappa agreement between RAPID3 remission and other SpA remission criteria was moderate (k: 0.46-0.56). The RAPID3 thresholds to define remission ranged from values ≤2 to ≤ 6 with areas under the ROC curves between 0.86 and 0.91. Female sex (OR 0.34, 95%CI: 0.12- 0.90, p= 0.031) and NSAIDs intake (OR 0.26, 95%CI: 0.10-0.66, p= 0.005) were independently associated with lower odds of achieving RAPID3 remission. Conclusion RAPID3 demonstrated construct validity in this cross-sectional study. This index can be useful for a more comprehensive assessment of axSpA in busy clinical settings.

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AB0233 Remission according to RAPID3 (routine assessment of patient index data 3) in patients with rheumatoid arthritis: a cross-sectional study from routine care at 3 usa sites

10.1136/annrheumdis-2017-eular.2749 ◽

2017 ◽

Author(s):

I Castrejon ◽

MJ Bergman ◽

KA Gibson ◽

Y Yazici ◽

JA Block ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Routine Care ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Index Data ◽

Routine Assessment

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AB0499 PHYSICAL ACTIVITY ASSESSMENT IN TUNISIAN PATIENTS WITH SPONDYLOARTHRITIS: THE IPAQ EVALUATION

Annals of the Rheumatic Diseases ◽

10.1136/annrheumdis-2021-eular.2053 ◽

2021 ◽

Vol 80 (Suppl 1) ◽

pp. 1277.1-1277

Author(s):

F. Majdoub ◽

M. Sellami ◽

S. Miladi ◽

A. Fazaa ◽

L. Souabni ◽

...

Keyword(s):

Physical Activity ◽

Disease Activity ◽

Axial Spondyloarthritis ◽

Cross Sectional Study ◽

Urban Setting ◽

Tnf Inhibitor ◽

Sectional Study ◽

Cross Sectional ◽

Tunisian Patients ◽

Different Levels

Background:The occurrence of Spondyloarthritis (SpA) often conditions patients’ quality of life and hinders their well-being. Physical activity (PA) is associated with various health-related benefits among adults with chronic inflammatory rheumatism but may be insufficiently performed.Objectives:This study aimed to assess PA in patients with SpA and explore its associated factors.Methods:This is a single-center cross-sectional study, involving patients with SpA, visiting our outpatient hospital over eight weeks. Patients responded to the International Physical Activity Questionnaire-Short form (IPAQ-S).Results:Sixty patients were included (39 M/21 F) with an average age of 45.8 years [25-78]. The mean duration of SpA was 13.2 years [1-25]. About 80% of patients were from an urban setting. Sixty-three percent of patients had a professional activity, while 13.3% were retired. Twenty-nine patients (48.3%) had axial and peripheral form, 18 patients (30%) had SpA with enteropathic arthritis, 8 (13.3%) with psoriatic arthritis, 3 patients (5%) had axial spondyloarthritis, and only 2 patients (3.3%) with SAPHO-Syndrom. About 23% of patients had hip arthritis and only 5% had uveitis. Fifty-eight patients were on TNF-inhibitor (21/58 Adalimumab, 15/58 Infliximab, 14/58 Etanercept, 8/58 Golimumab). The average BASDAI was 2.7/10. The average ASDASCRP was 2.1/10. The average BASFI was 3.3/10. IPAQ results were distributed as follows: 78.3% of patients were in the « low physical activity » category, 21.7% were in the « moderate physical activity » while none of the patients were in the « high physical activity ». Patients without employment had lower levels of physical activity (29.7%) but no association was observed between those two items (p=0.082). Disease activity objectified with BASDAI was related to low physical activity (p=0.045) whereas no association was observed with ASDASCRP (p=0.870) or BASFI (p=0.056). Otherwise, TNF-inhibitor treatment was not related to different levels of PA (p=0.09).Conclusion:Tunisian patients with SpA don’t perform enough physical activity. Except for high disease activity, the different levels of PA did not appear to be explained by other disease-related variables. Thereby, physical activity should be encouraged in SpA.References:[1]Fabre, S., Molto, A., Dadoun, S. et al. Physical activity in patients with axial spondyloarthritis: a cross-sectional study of 203 patients. Rheumatol Int 36, 1711–1718 (2016).Disclosure of Interests:None declared.

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BALANCE AND FALLS IN AXIAL SPONDYLOARTHRITIS: A CROSS SECTIONAL STUDY.

10.5151/sbr2019-349 ◽

2019 ◽

Author(s):

KERILYN BRENDA MEWES ◽

BETANIA LONGO ◽

ANA PAULA BECKHAUSER CAMPOS ◽

JULIANA SIMIONI ◽

THELMA LAROCCA SKARE

Keyword(s):

Axial Spondyloarthritis ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional

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Construct validity of the Levels of Emotional Awareness Scale among women high in eating disorder symptoms: a cross-sectional study

Eating and Weight Disorders - Studies on Anorexia Bulimia and Obesity ◽

10.1007/s40519-020-00945-0 ◽

2020 ◽

Author(s):

Jillon S. Vander Wal ◽

Zachary A. Soulliard ◽

Alicia A. Kauffman

Keyword(s):

Eating Disorder ◽

Construct Validity ◽

Emotional Awareness ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Eating Disorder Symptoms

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Utility and feasibility of integrating pulse oximetry into the routine assessment of young infants at primary care clinics in Karachi, Pakistan: a cross-sectional study

BMC Pediatrics ◽

10.1186/s12887-015-0463-z ◽

2015 ◽

Vol 15 (1) ◽

Cited By ~ 7

Author(s):

Connor A. Emdin ◽

Fatima Mir ◽

Shazia Sultana ◽

AM Kazi ◽

Anita K M Zaidi ◽

...

Keyword(s):

Primary Care ◽

Pulse Oximetry ◽

Cross Sectional Study ◽

Sectional Study ◽

Cross Sectional ◽

Primary Care Clinics ◽

Young Infants ◽

Routine Assessment

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Prevalence of self-reported versus diagnosed dentinal hypersensitivity: a cross-sectional study and ROC curve analysis

Acta Odontologica Scandinavica ◽

10.1080/00016357.2018.1536804 ◽

2019 ◽

Vol 77 (3) ◽

pp. 219-223 ◽

Cited By ~ 2

Author(s):

Nayara Franciele Figueiredo Barroso ◽

Polyana Matos Alcântara ◽

Adriana Maria Botelho ◽

Dhelfeson Willya Douglas-de-Oliveira ◽

Patrícia Furtado Gonçalves ◽

...

Keyword(s):

Roc Curve ◽

Cross Sectional Study ◽

Curve Analysis ◽

Sectional Study ◽

Roc Curve Analysis ◽

Cross Sectional ◽

Dentinal Hypersensitivity

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Neck Circumference as an Anthropometric Indicator of Central Obesity in Patients with Prediabetes: A Cross-Sectional Study

BioMed Research International ◽

10.1155/2019/4808541 ◽

2019 ◽

Vol 2019 ◽

pp. 1-8 ◽

Cited By ~ 4

Author(s):

Thunyarat Anothaisintawee ◽

Nakarin Sansanayudh ◽

Sangsulee Thamakaison ◽

Dumrongrat Lertrattananon ◽

Ammarin Thakkinstian

Keyword(s):

Waist Circumference ◽

Central Obesity ◽

Cross Sectional Study ◽

Neck Circumference ◽

Youden Index ◽

Sectional Study ◽

Roc Curve Analysis ◽

Cross Sectional ◽

Pairwise Correlation ◽

Glucose Levels

Measurement of waist circumference has substantial variability and some limitations, while neck circumference is a simple and reliable anthropometric measure. This study aimed to assess the association between neck circumference and waist circumference and to identify the best cutoff of neck circumference that could predict central obesity in prediabetic patients. This cross-sectional study included adult patients with prediabetes, defined as having fasting plasma glucose levels ranging from 100 to 125 mg/dL or HbA1c ranging from 5.7 to 6.49%, who visited the outpatient clinic of Family Medicine Department, Ramathibodi Hospital, Thailand, during October 2014 and March 2016. Neck circumference was measured from the level just below the laryngeal prominence perpendicular to the long axis of the neck. Central obesity was defined as having waist circumference measurements greater than 90 and 80 cm for males and females, respectively. The correlation between neck circumference and waist circumference was explored by applying pairwise correlation coefficient. Receiver operating characteristic (ROC) curve analysis was performed and Youden index equal to “sensitivity – (1-specificity)” was calculated. Neck circumference that yielded the maximum Youden index was determined as the optimal cutoff point for prediction of central obesity. There were 1,534 patients eligible for this study. After adjusting for covariables, neck circumference was found to be significantly associated with waist circumference in both females and males, with β-coefficients of 1.01 (95% CI: 0.83, 1.20) and 0.65 (95% CI: 0.46, 0.85), respectively. After applying the ROC analysis, neck circumferences ≥ 32 cm in females and ≥ 38 cm in males were determined as the best cutoff values to predict central obesity. Neck circumference is strongly correlated with waist circumference in prediabetics and should be considered as an alternative to the waist circumference measurement in screening for central obesity.

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Cross-sectional study of patients with axial spondyloarthritis fulfilling imaging arm of ASAS classification criteria: baseline clinical characteristics and subset differences in a single-centre cohort

BMJ Open ◽

10.1136/bmjopen-2018-024713 ◽

2019 ◽

Vol 9 (4) ◽

pp. e024713 ◽

Cited By ~ 2

Author(s):

Kristyna Bubová ◽

Šárka Forejtová ◽

Kateřina Zegzulková ◽

Monika Gregová ◽

Markéta Hušáková ◽

...

Keyword(s):

Disease Activity ◽

Axial Spondyloarthritis ◽

Cross Sectional Study ◽

Classification Criteria ◽

Spinal Mobility ◽

Sectional Study ◽

Single Centre ◽

Peripheral Arthritis ◽

Cross Sectional ◽

Asas Classification Criteria

ObjectiveThis study compared demographic, clinical and laboratory characteristics between patients with radiographic and non-radiographic axial spondyloarthritis (axSpA).MethodsIn this single-centre cross-sectional study, a total of 246 patients with axSpA fulfilling the imaging arm of Assessment of SpondyloArthritis International Society classification criteria were recruited. A total of 140 patients were diagnosed as non-radiographic axial spondyloarthritis (nr-axSpA), and 106 patients had ankylosing spondylitis (AS). Sociodemographic characteristics, disease manifestations, clinical and laboratory disease activity and their differences between subsets were analysed. P values below 0.05 with CI 95% were considered statistically significant.ResultsMore nr-axSpA patients were women (61.4%) compared with 24.7% of AS patients. First symptoms developed earlier in AS patients compared with nr-axSpA (23.0 (IQR 17.5–30.0) vs 27.8 (IQR 21.0–33.7) years, p=0.001). Disease manifestations did not differ, but patients with nr-axSpA experienced peripheral arthritis more frequently (35.7% vs 17.0%, p=0.001) with less hip involvement (8.6% vs 18.9%, p=0.022) compared with patients with AS. Patients with AS exhibited worse spinal mobility and physical function compared with nr-axSpA. AS Disease Activity Scores and CRP levels were significantly higher in patients with AS compared with nr-axSpA (2.4 (IQR 1.7–2.8) vs 2.0 (IQR 1.1–2.3), p=0.022 and 7.1 (IQR 2.6–14.9) vs 2.5 (IQR 0.8–8.2) mg/L, p<0.001, respectively).ConclusionsOur data demonstrated some known and also novel differences between the two imaging arm fulfilling axSpA subgroups. Non-radiographic patients were mostly women who had experienced shorter disease duration, milder disease activity and better functional status with less hip involvement but more peripheral arthritis compared with patients with AS.

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