scholarly journals Expression and clinical implications of P53, P63, and P73 protein in malignant tumor of the parotid gland

2014 ◽  
Vol 44 ◽  
pp. 875-882 ◽  
Author(s):  
Mei YONG ◽  
Ling YANG ◽  
Qimuge SUYILA ◽  
Wenyan HAN ◽  
Hongwei YUAN ◽  
...  
1995 ◽  
Vol 88 (7) ◽  
pp. 899-904
Author(s):  
Koji SHIROTORI ◽  
Nobuhisa TERADA ◽  
Akiyoshi KONNO ◽  
Kiyoshi TOGAWA

2017 ◽  
Vol 5 (2.3) ◽  
pp. 4002-4005
Author(s):  
Manisha Nakhate ◽  
◽  
Rupali Shastrakar ◽  
V G Sawant ◽  
Joy Ghosal ◽  
...  

2012 ◽  
Vol 2 (4) ◽  
pp. 331-334
Author(s):  
S Shrestha ◽  
CB Pun ◽  
R Basyal ◽  
T Pathak ◽  
S Bastola ◽  
...  

Polymorphous low-grade adenocarcinoma is a rare salivary gland malignant tumor of low aggressiveness, commonly occurring in minor salivary glands. Its origin in major salivary glands is considered exceedingly rare. We report a case of polymorphous low grade adenocarcinoma arising from left parotid in a 21-yearold female patient.Journal of Pathology of Nepal (2012) Vol. 2, 331-334DOI: http://dx.doi.org/10.3126/jpn.v2i4.6890


1989 ◽  
Vol 75 (6) ◽  
pp. 537-541 ◽  
Author(s):  
Ante Roguljić ◽  
Tayfour Safwan ◽  
Viktor Šeparović

Creatine kinase (CK EC 2.7.3.2) and CK-BB activity was analyzed in 41 malignant tumors of 6 different sites and different histological structures. The same analyses were done on 150 sera of patients with malignant diseases of various localizations. The rate of CK activity was determined kinetical-ly, whereas tissue and serum CK-BB were separated chromatographically (Mercer). Insofar as malignant tumor tissues are concerned, the highest average rate of CK-BB activity was detected in tumors of the prostate (mean 1450 IU/g), and the lowest in tumors of the parotid gland (mean 5.2 IU/g). CK-BB was detected by the Mercer technique in 56 (37.3 %) of 150 analyzed sera of patients with malignant diseases. The rate of CK activity in sera of patients with malignant diseases was 8 to 74 IU/I. In comparison with the site of the malignant process no significant CK serum activity differences were observed. T2-T3 tumors did not significantly influence the activity of either CK or CK-BB in the case of either tissues or sera (T1-T3). Enzyme activity was found to be much higher - both in tumoral tissue and in sera - with T4 tumors. The highest rate of CK-BB activity was found in sera of patients with malignant tumors of the stomach (mean 8.1 IU/I), and the lowest in malignant tumors of the rectum (mean 1.8 IU/I).


1994 ◽  
Vol 87 (6) ◽  
pp. 783-787
Author(s):  
Yuji Imate ◽  
Hirotaka Hara ◽  
Masahiro Takahashi ◽  
Takeshi Sagara ◽  
Junji Nakano

2020 ◽  
Vol 27 (01) ◽  
pp. 80-83
Author(s):  
Agha Taj Mohammed ◽  
Sajda Khuhawar ◽  
Bibi Gulsama ◽  
Salman Shams

Objectives: To evaluate epidemiological pattern, early diagnostic tool and histological type of parotid gland tumors. Study Design: Prospective cross sectional study. Setting: Department of Oral & Maxillofacial Surgery& General Surgery Liaquat University hospital Hyderabad. Period: From 2013 to 2017. Material & Methods: Study contains 67 patients of parotid tumors after initial diagnosis. These patients were first diagnosed by FNAC (Fine needle aspiration cytology) along with CT scan & MRI where required. Final diagnosis was established after histopathological diagnosis of tumor. Results: Males were predominantly involved in both tumor patterns. Most common age group was 5th decade in both benign and malignant tumors. FNAC has diagnostic sensitivity of almost 90-97%. Out of 67, 51 tumors were benign and 16 were malignant. Pleomorphic adenoma was the most common benign tumor while mucoepidermoid carcinoma was found as most received malignant tumor. Conclusion: Pleomorphic adenoma is most commonly found benign tumor and mucoepidermoid carcinoma is found more in numbers as malignant tumor.


2016 ◽  
pp. 130-130
Author(s):  
Nirmal Soni ◽  
Lokesh Bhama

2014 ◽  
Vol 2014 ◽  
pp. 1-3 ◽  
Author(s):  
Salih Aydın ◽  
Umit Taskin ◽  
Kadir Ozdamar ◽  
Kadir Yücebas ◽  
Mehmet Sar ◽  
...  

Dedifferentiation is defined as high-grade malignant tumor development out of a low-grade malignant tumor. We present an adenocarcinoma tumor of the parotid gland that was dedifferentiated from a low-grade epithelial-myoepithelial carcinoma and was followed up for 3 years. Our patient, a 46-year-old female, presented with a left parotid mass of 20-year duration. Histopathologic results showed that there was only one area of typical epithelial-myoepithelial carcinoma, with foci of poorly differentiated adenocarcinoma (not otherwise specified; NOS) and clear cytoplasm in the parotid gland. Immunohistochemical staining results showed SMA (+), P63 (+), CK8 (+), and S100 (+) on epithelial cells. A review of the literature revealed 22 previously reported cases of dedifferentiated epithelial-myoepithelial carcinoma. In these cases, the malignant tumors that dedifferentiated from epithelial-myoepithelial carcinoma were adenoid cystic carcinoma, actinic cell carcinoma, polymorphous low-grade adenocarcinoma, mucoepidermoid carcinoma, and intraductal carcinoma. In our case, the malignant tumor that dedifferentiated from the epithelial-myoepithelial carcinoma was a poorly differentiated adenocarcinoma. Histopathological results showed that metastases were not seen in the neck-dissection material. As a result, our case will make a contribution to the literature in terms of prognosis, because there are very few reported cases of dedifferentiated adenocarcinoma development arising from epithelial-myoepithelial carcinoma.


Sign in / Sign up

Export Citation Format

Share Document