scholarly journals Parotid gland tumors an evaluation at Tertiary Care Hospital.

2020 ◽  
Vol 27 (01) ◽  
pp. 80-83
Author(s):  
Agha Taj Mohammed ◽  
Sajda Khuhawar ◽  
Bibi Gulsama ◽  
Salman Shams
Keyword(s):  
Parotid Gland ◽  
Pleomorphic Adenoma ◽  
Malignant Tumor ◽  
Mucoepidermoid Carcinoma ◽  
Benign Tumor ◽  
Tertiary Care ◽  
Maxillofacial Surgery ◽  
Histopathological Diagnosis ◽  
Care Hospital ◽  
Parotid Gland Tumors

Objectives: To evaluate epidemiological pattern, early diagnostic tool and histological type of parotid gland tumors. Study Design: Prospective cross sectional study. Setting: Department of Oral & Maxillofacial Surgery& General Surgery Liaquat University hospital Hyderabad. Period: From 2013 to 2017. Material & Methods: Study contains 67 patients of parotid tumors after initial diagnosis. These patients were first diagnosed by FNAC (Fine needle aspiration cytology) along with CT scan & MRI where required. Final diagnosis was established after histopathological diagnosis of tumor. Results: Males were predominantly involved in both tumor patterns. Most common age group was 5th decade in both benign and malignant tumors. FNAC has diagnostic sensitivity of almost 90-97%. Out of 67, 51 tumors were benign and 16 were malignant. Pleomorphic adenoma was the most common benign tumor while mucoepidermoid carcinoma was found as most received malignant tumor. Conclusion: Pleomorphic adenoma is most commonly found benign tumor and mucoepidermoid carcinoma is found more in numbers as malignant tumor.

scholarly journals Histopathological spectrum and outcome of surgery for salivary gland tumors presented in tertiary care hospital of Pakistan.

2021 ◽  
Vol 28 (10) ◽  
pp. 1418-1421
Author(s):  
Ahmed Siddique Ammar ◽  
Rizwan Khalid ◽  
Syed Asghar Naqi ◽  
Shehrbano Khattak ◽  
Farwa Inayat ◽  
...  
Keyword(s):  
Salivary Gland ◽  
Parotid Gland ◽  
Pleomorphic Adenoma ◽  
Benign Tumor ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Salivary Gland Tumors ◽  
Care Hospital ◽  
Outcome Of Surgery ◽  
Malignant Salivary Gland Tumors

Objective: This study is aimed to know the histopathological spectrum and outcome of surgery for salivary gland tumors presented in a tertiary care hospital of Pakistan. Study Design: Retrospective study. Setting: Tertiary Care Hospital of Pakistan. Period: July 2018 to June 2020. Material & Methods: After approval from Institutional Review Board. Total 73 patients were selected with preoperative diagnosis of salivary gland tumors with consecutive non probability sampling. All surgical procedures were done by specialist general surgeons who had experience of more than 10 years of head and neck surgery. Results: Male to female ratio was 2:1 with mean age of patients was 46 years. Among males 29 (59.1%) were benign salivary gland tumors while 20 (40.81%) were malignant salivary gland tumors. Among females 13 (54.16%) were benign and 11 (45.83%) were malignant salivary gland tumors Most common benign tumor was pleomorphic adenoma 32 (43.8%) while mucoepidermoid carcinoma was most common malignant tumor 17 (23.28%). Only 9 (12.32%) patients experienced nerve paresis. Conclusion: Male preponderance, a relatively younger age at presentation and single predominant benign tumor (pleomorphic adenoma) were the significant findings. Majority of them were found in parotid gland and found to be benign in nature. Majority of them were found in parotid gland and found to be benign in nature. Although fine needle aspiration cytology and magnetic resonance imaging provide some useful information about the nature of tumor but most of them will acquire a surgical excision in order to find the definitive diagnosis.

scholarly journals Histopathological Analysis of Neoplastic and Non Neoplastic Lesions of Salivary Gland – A Retrospective Study in a Tertiary Care Hospital

2021 ◽  
Vol 8 (05) ◽  
pp. 236-240
Author(s):  
Sheela K.M ◽  
Priya V.S. ◽  
Lali K. Rajan ◽  
Ashida M. Krishnan
Keyword(s):  
Salivary Gland ◽  
Pleomorphic Adenoma ◽  
Mucoepidermoid Carcinoma ◽  
Histopathological Examination ◽  
Tertiary Care ◽  
Malignant Neoplasm ◽  
Histopathological Analysis ◽  
Low Grade ◽  
Care Hospital ◽  
Neoplastic Lesions

BACKGROUND Salivary gland lesions constitute less than 1 % of tumours and about 4 % of all epithelial neoplasms of head and neck region. These comprise of a wide variety of benign, malignant and non-neoplastic lesions which exhibits a difference in histological behaviour. There are no reliable criteria to differentiate on clinical grounds the benign from malignant ones. So morphological evaluation is necessary. We aim to study the frequency of various salivary gland lesions in sialoadenectomy specimens and categorise them into neoplastic and nonneoplastic lesions. METHODS It is a record based retrospective 5-year study carried out in the Government Medical College, Thiruvananthapuram, Kerala, from January 2014 to December 2018. RESULTS In this study a total of 329 histopathologically proven cases of salivary gland lesions were included. Neoplastic lesions and non-neoplastic lesions constituted 78.42 % and 21.58 % respectively. Pleomorphic adenoma was the most common neoplasm (50.54 %) trailed by Warthin’s tumour (9.73 %). Most common malignant neoplasm encountered in our study was mucoepidermoid carcinoma (9.73 %) among which low grade tumours showed predominance. We observed significantly higher incidence of benign and malignant lesions in the 5 th to 6th decade while non neoplastic lesions were seen more in the 4th to 5th decade. Average age of the patients with salivary gland tumours was 46.12  SD 15.57. Majority of cases of salivary gland lesions in our study were from parotid gland (75.68 %) followed by submandibular gland 24.01 %. CONCLUSIONS Pleomorphic adenoma was the most common benign tumour in our study and mucoepidermoid carcinoma the most common malignant tumour. Neoplastic lesions showed a predominance over non neoplastic lesions. Histopathological examination is the mainstay for diagnosis and clinical management. KEYWORDS Histopathology, Pleomorphic Adenoma, Mucoepidermoid Carcinoma

scholarly journals Spectrum of biopsied oral and maxillofacial lesions in a tertiary care hospital of Karachi, Pakistan

2021 ◽  
Vol 15 (2) ◽  
pp. 81-86
Author(s):  
Syeda Hala Raza ◽  
Sufyan Ahmed ◽  
Maryam Zafar
Keyword(s):  
Buccal Mucosa ◽  
Soft Tissues ◽  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Maxillofacial Surgery ◽  
Oral And Maxillofacial Surgery ◽  
Histopathological Diagnosis ◽  
Care Hospital ◽  
Hard Tissue ◽  
Female Ratio

Objectives: The burden of benign and malignant maxillofacial lesions in developing countries has increased rapidly over the years. Objective of this study was to provide a spectrum of oral and maxillofacial lesions biopsied in a tertiary care hospital of Karachi, Pakistan and to contribute in baseline data of target population. Patients and methods: This descriptive cross sectional study was made of biopsies performed in patients presenting to OPD of Oral and Maxillofacial Surgery Department, Abbasi Shaheed Hospital Karachi, Pakistan, between July 2018 till June 2020. A total of 652 patients belonging to either gender, 18-75 years of age, incisional or excisional biopsy were included. Recurrent or previously diagnosed lesions and patients not willing to give informed consent were excluded. Data including age, gender, site and histopathological diagnosis was recorded on a performa. Descriptive statistical analysis was done using SPSS version 26. Result: Out of 652 biopsies performed, (82.9%, n=541) belonged to soft tissues and (17.1%, n=111) were hard tissue lesions. The mean age of patients was 41.82 years, with a male to female ratio of 2.9:1. The most frequent sites biopsied were buccal mucosa (50.9%, n=332) and posterior mandible (10.6%, n=69). Oral squamous cell carcinoma (OSCC) (55.1%, n=359) was the most commonly reported soft tissue lesion with major involved sites buccal mucosa (74.4%, n=267), dentoalveolar mucosa (8%, n=29) and lateral border of tongue (7.2%, n=26) and for hard tissue the most common lesion was ameloblastoma of posterior mandible (3.5%, n=23). Conclusion: This study provides useful information about distribution of oral and maxillofacial lesions and highlights OSCC as the single most frequent diagnosis involving a much younger male population.

scholarly journals Spectrum of primary epithelial tumors of major salivary glands: a 5 year record based descriptive study from a tertiary care centre

2017 ◽  
Vol 4 (2) ◽  
pp. 562
Author(s):  
Jayalakshmy Payippat Leelamma ◽  
Bhavya P. Mohan
Keyword(s):  
Salivary Gland ◽  
Parotid Gland ◽  
Salivary Glands ◽  
Pleomorphic Adenoma ◽  
Mucoepidermoid Carcinoma ◽  
Malignant Tumors ◽  
Tertiary Care ◽  
Benign Tumors ◽  
Care Centre ◽  
Tertiary Care Centre

Background: Salivary gland tumors constitute a highly heterogeneous histopathologic group. There are few epidemiological studies of large series of benign and malignant epithelial tumors of major salivary glands in South India.Methods: This is a retrospective study in a tertiary care centre in Kerala, South India. A total of 180 epithelial neoplasms of major salivary gland were studied over a 5 year period. In each case age, sex, anatomical location and histopathological diagnosis were recorded.Results: Patients with benign and malignant tumors presented with a mean age of 52.3 and 55.9 years respectively. The frequency of benign tumors was 80.6% (n = 145) and of malignant tumors was 19.4% (n = 35). There was a higher prevalence of tumors in males 60.6% (n = 109) than in females 39.4% (n = 71). 91.9% (n = 164) of the tumors were localized in the parotid gland, 8.3% (n = 15) in the submandibular gland and 0.6% (n = 1) in the sublingual gland. The most common benign tumors were Pleomorphic adenoma (48.9%, n = 88) and Warthin’s tumor (28.9%, n = 52). Among malignant tumors, Mucoepidermoid carcinoma was the most common (9.5%, n = 17) followed by Carcinoma ex pleomorphic adenoma (2.8%, n = 5) and adenoid cystic carcinoma (2.2%, n = 4).Conclusions: Parotid gland was the most common site of both benign and malignant tumours. Plemorphic adenoma was the most common benign tumor and mucoepidermoid carcinoma was the most common malignant tumor.

scholarly journals Deep Learning for Differentiating Benign From Malignant Parotid Lesions on MR Images

2021 ◽  
Vol 11 ◽  
Author(s):  
Xianwu Xia ◽  
Bin Feng ◽  
Jiazhou Wang ◽  
Qianjin Hua ◽  
Yide Yang ◽  
...  
Keyword(s):  
Deep Learning ◽  
Parotid Gland ◽  
Pleomorphic Adenoma ◽  
Malignant Tumor ◽  
Training Dataset ◽  
Validation Dataset ◽  
Benign Tumors ◽  
Mr Images ◽  
Warthin Tumor ◽  
Parotid Gland Tumors

Purpose/Objectives(s)Salivary gland tumors are a rare, histologically heterogeneous group of tumors. The distinction between malignant and benign tumors of the parotid gland is clinically important. This study aims to develop and evaluate a deep-learning network for diagnosing parotid gland tumors via the deep learning of MR images.Materials/MethodsTwo hundred thirty-three patients with parotid gland tumors were enrolled in this study. Histology results were available for all tumors. All patients underwent MRI scans, including T1-weighted, CE-T1-weighted and T2-weighted imaging series. The parotid glands and tumors were segmented on all three MR image series by a radiologist with 10 years of clinical experience. A total of 3791 parotid gland region images were cropped from the MR images. A label (pleomorphic adenoma and Warthin tumor, malignant tumor or free of tumor), which was based on histology results, was assigned to each image. To train the deep-learning model, these data were randomly divided into a training dataset (90%, comprising 3035 MR images from 212 patients: 714 pleomorphic adenoma images, 558 Warthin tumor images, 861 malignant tumor images, and 902 images free of tumor) and a validation dataset (10%, comprising 275 images from 21 patients: 57 pleomorphic adenoma images, 36 Warthin tumor images, 93 malignant tumor images, and 89 images free of tumor). A modified ResNet model was developed to classify these images. The input images were resized to 224x224 pixels, including four channels (T1-weighted tumor images only, T2-weighted tumor images only, CE-T1-weighted tumor images only and parotid gland images). Random image flipping and contrast adjustment were used for data enhancement. The model was trained for 1200 epochs with a learning rate of 1e-6, and the Adam optimizer was implemented. It took approximately 2 hours to complete the whole training procedure. The whole program was developed with PyTorch (version 1.2).ResultsThe model accuracy with the training dataset was 92.94% (95% CI [0.91, 0.93]). The micro-AUC was 0.98. The experimental results showed that the accuracy of the final algorithm in the diagnosis and staging of parotid cancer was 82.18% (95% CI [0.77, 0.86]). The micro-AUC was 0.93.ConclusionThe proposed model may be used to assist clinicians in the diagnosis of parotid tumors. However, future larger-scale multicenter studies are required for full validation.

Clinico-pathological profile of ovarian cysts in a tertiary care hospital

2017 ◽  
Vol 6 (10) ◽  
pp. 4642 ◽  
Author(s):  
Sairem Mangolnganbi Chanu ◽  
Biswajit Dey ◽  
Vandana Raphael ◽  
Subrat Panda ◽  
Yookarin Khonglah
Keyword(s):  
Tertiary Care Hospital ◽  
Tertiary Care ◽  
Lower Abdominal Pain ◽  
Cystic Teratoma ◽  
Serous Cystadenoma ◽  
Mature Cystic Teratoma ◽  
Ovarian Cysts ◽  
Histopathological Diagnosis ◽  
Care Hospital ◽  
North East

Background: Ovarian cystic neoplasms are common in gynaecological practice. These may pose diagnostic difficulty to the pathologists. This study was conducted to analyse the clinical and histological profile of ovarian cystic neoplasms.Methods: This is a retrospective study done from January 2016 to April 2017 in a tertiary care hospital in North East India. All the patients, who were clinically and radiologically diagnosed as ovarian cysts, which had histopathological confirmation were included in the study. Data including the age, parity, clinical symptoms, laterality and histopathological findings were analysed.Results: A total of 101 patients operated for ovarian cysts in the study period were analysed. The most common clinical presentation was lower abdominal pain. There were 11 (10.9%) malignant cases, 4 (4%) were intermediate grade and borderline in nature, and 85 (84.1%) cases were benign in nature. There was 1 (1%) case of metastasis to ovary. Mature cystic teratoma was most common (20.8%) histopathological diagnosis. The second most common cyst was serous cystadenoma (19.8%).Conclusion: Ovarian cysts are commonly encountered in gynaecological practice and equally encountered by the pathologists. Most commonly found ovarian cysts were mature cystic teratoma followed by serous cystadenoma.

scholarly journals Mastoid Bone involved by Pleomorphic Adenoma

2016 ◽  
Vol 8 (3) ◽  
pp. 111-112
Author(s):  
Pradipta K Parida
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Parotid Gland ◽  
Pleomorphic Adenoma ◽  
Surgical Planning ◽  
Benign Tumor ◽  
Review Of Literature ◽  
Resonance Imaging ◽  
Mastoid Bone ◽  
Magnetic Resonance Imaging Mri

ABSTRACT Pleomorphic adenoma is a benign tumor of the salivary glands, most commonly affecting the parotid gland. Pleomorphic adenoma of the ear is rare. The use of imaging modalities, especially magnetic resonance imaging (MRI), is particularly useful in localizing and surgical planning of these tumors. We present a case of pleomorphic adenoma invading the mastoid cortical bone, with review of literature. How to cite this article Vamanshankar H, Parida PK. Mastoid Bone involved by Pleomorphic Adenoma. Int J Otorhinolaryngol Clin 2016;8(3):111-112.

scholarly journals Conjunctival Lesions: A 5-Year Basic Demographic Data and Clinicopathological Review in a Tertiary Eye Care Hospital

2021 ◽  
Author(s):  
Hind M. Alkatan ◽  
Khalid M. Alshomar ◽  
Hala A. Helmi ◽  
Wajda M. Alhothali ◽  
Abdulaziz M. Alshalan
Keyword(s):  
Wide Spectrum ◽  
Care Center ◽  
Demographic Data ◽  
Tertiary Care ◽  
Malignant Lesion ◽  
Histopathological Diagnosis ◽  
Care Hospital ◽  
Adult Males ◽  
Duration Of Symptoms ◽  
Malignant Lesions

Abstract Background Conjunctival lesions are common with a wide spectrum of benign, premalignant, and malignant lesions. Few histopathological studies have been conducted on conjunctival lesions with variable designs and results. Our aim in this study is to provide information on common conjunctival lesions seen in an ophthalmology tertiary care center in Saudi Arabia. Methods A retrospective, observational study of all consecutive conjunctival tissue specimens sent for histopathological assessment to the pathology department from 2015 to 2019 were analyzed. Clinical data were collected from medical records, and the histopathological slides were reviewed by a single pathologist. Results A total of 110 conjunctival specimens from 108 patients were included (mean age: 53 years, 67 males and 43 females). Bilateral involvement was mostly found in inflammatory lesions (40%). Most lesions were benign (91%), with a significantly longer duration of symptoms in malignant lesions (p = 0.036*). The clinical diagnosis matched the final histopathological diagnosis in 75.5% of the total specimens. The most frequent category of benign lesions was fibrodegenerative and proliferative lesions (53.6%), with a significantly higher prevalence among adult males (p < 0.001). Melanocytic lesions were more common in children (33.3%) than adults (9.8%), and the mean age of children was significantly lower (p = 0.013). The most frequent malignant lesion was ocular surface squamous neoplasia (50%), with equal prevalence among males and females. The overall outcome was favorable in 89.4% and unfavorable in 10.6%, mostly due to surgical complications, further progression of the lesion, or recurrence. Conclusion This study shows variability in the frequency of conjunctival lesions based on gender, age, geographical, racial, and environmental factors. There has been a shift in the gender-based prevalence of ocular squamous neoplasia over the last three decades, probably due to a change in lifestyle.

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