scholarly journals A Case of Encapsulating Peritoneal Sclerosis Treated by Intestinal Adhesion Dissection

2021 ◽  
Vol 82 (5) ◽  
pp. 983-987
Author(s):  
Hiroshi HADATSUKI ◽  
Norimitsu YABUSAKI ◽  
Akiharu ISHIYAMA ◽  
Toshiaki MORI ◽  
Masashi HIROTA ◽  
...  
Keyword(s):  
Intestinal Adhesion

The cholinergic nervous system plays an important role in rat postoperative intestinal adhesion

Surgery ◽  
2008 ◽  
Vol 143 (2) ◽  
pp. 226-232 ◽  
Author(s):  
Yohei Tokita ◽  
Mitsutoshi Yuzurihara ◽  
Kazuko Satoh ◽  
Seiichi Iizuka ◽  
Sachiko Imamura ◽  
...  
Keyword(s):  
Nervous System ◽  
Intestinal Adhesion

scholarly journals Danhong Injection Alleviates Postoperative Intra-abdominal Adhesion in a Rat Model

2019 ◽  
Vol 2019 ◽  
pp. 1-11 ◽  
Author(s):  
Yunhua Wu ◽  
Guangbing Wei ◽  
Junhui Yu ◽  
Zilu Chen ◽  
Zhengshui Xu ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Rat Model ◽  
Transforming Growth Factor ◽  
High Dose ◽  
Collagen Deposition ◽  
Abdominal Adhesions ◽  
Abdominal Adhesion ◽  
Danhong Injection ◽  
Intestinal Adhesion ◽  
And Oxidative Stress

Background. Among all the common complications that occur after abdominal surgery, intestinal adhesion is perhaps the most unpleasant one. However, current methods to treat and prevent intestinal adhesion are limited; thus, exploring new methods to prevent and treat intestinal adhesion is greatly needed. In this study, we demonstrated that Danhong injection (DHI) may be used as a promising method to prevent and treat intra-abdominal adhesion in a rat model. Materials and Methods. Forty-eight rats were randomly divided into six groups. Except for the sham-operated group, all rats underwent cecal abrasion to establish an adhesion model. After the operation, the rats in the DHI-treated groups received different doses of DHI via the tail vein daily, while the other group was treated with the same volume of saline solution. Seven days after the operation, all rats were sacrificed, and the degree of adhesion was evaluated by Nair’s scoring system. The extent of inflammation in the adhesion tissue was detected by HE staining and the expression of tumor necrosis factor-α (TNF-α) and transforming growth factor-β (TGF-β). The collagen deposition was assessed by Sirius red staining and α-SMA, MMP9, t-PA, and PAI-1 levels. Oxidative stress was indicated by the level of reactive oxygen species (ROS) in adhesion tissues and by immunohistochemical labeling of Nrf2. Furthermore, rat primary peritoneal mesothelial cells (RPMCs) were treated with H2O2 and DHI, and NF-κB phosphorylation was detected to illustrate the effect of DHI on oxidative stress. Results. The intra-abdominal adhesion scores were significantly decreased in the groups treated with a high dose of DHI compared with the control groups, and the degree of inflammation, fibrosis, and oxidative stress was also significantly decreased. DHI treatment significantly reduced the levels of TNF-α, TGF-β1, and PAI and increased the expression levels of MMP9, Nrf2, and t-PA in the adhesion tissues. ROS levels and NF-κB phosphorylation were significantly reduced in DHI-treated RPMCs compared with the control RPMCs. Conclusion. DHI alleviates the formation of postoperative intra-abdominal adhesions by inhibiting inflammation, collagen deposition, and oxidative stress in a rat model and may serve as a promising drug to prevent intra-abdominal adhesions.

scholarly journals Medical Aspect of Intestinal Adhesion and Ptoses

1912 ◽  
Vol 167 (11) ◽  
pp. 353-358
Author(s):  
JAMES MARSH JACKSON
Keyword(s):  
Medical Aspect ◽  
Intestinal Adhesion

ULTRASOUND DIAGNOSIS: ABDOMINAL WALL INTESTINAL ADHESION IN A HOLSTEIN COW

1996 ◽  
Vol 37 (4) ◽  
pp. 300-301 ◽  
Author(s):  
R.L. Tucker ◽  
A. Fortner ◽  
J.W. Tyler ◽  
S.M. Parish ◽  
C.E. Dunigan
Keyword(s):  
Abdominal Wall ◽  
Ultrasound Diagnosis ◽  
Holstein Cow ◽  
Intestinal Adhesion

scholarly journals Adhesion ofAeromonassp. to cell lines used as models for intestinal adhesion

1995 ◽  
Vol 115 (3) ◽  
pp. 465-473 ◽  
Author(s):  
S. M. Kirov ◽  
L. J. Hayward ◽  
M. A. Nerrie
Keyword(s):  
Cell Lines ◽  
Indirect Evidence ◽  
Intestinal Cell ◽  
Trypsin Treatment ◽  
Aeromonas Veronii ◽  
Intestinal Cell Line ◽  
Intestinal Origin ◽  
Intestinal Adhesion ◽  
Mechanical Shearing ◽  
Intestinal Enterocytes

SummaryAdhesion to HEp-2 cells has been shown to correlate with enteropathogenicity forAeromonasspecies. Such adhesion is thought to reflect the ability of strains to adhere to human intestinal enterocytes, although HEp-2 cells are not of intestinal origin. In this study strains ofAeromonas veroniibiotype sobria isolated from various sources were investigated in parallel assays for their ability to adhere to HEp-2 cells and to an intestinal cell line (Caco-2). Quantitative assays showed identical adhesion values were obtained with both cell lines. Adhesion was best when bacteria were grown at 22 °C compared with 37 °C and 7 °C. Some environmental isolates showed greater adhesion when grown at 7 °C than when grown at 37 °C. Filamentous structures on these strains are also optimally expressed under the above conditions (reported elsewhere). Mechanical shearing or trypsin treatment to remove surface structures from several adhesive strains grown at 22 °C decreased adhesion to cell lines by 50–80% providing further indirect evidence that filamentous adhesins may play a role in cell adhesion for thisAeromonasspecies.

scholarly journals Transcriptional Response and Enhanced Intestinal Adhesion Ability of Lactobacillus rhamnosus GG after Acid Stress

2018 ◽  
Vol 28 (10) ◽  
pp. 1604-1613 ◽  
Author(s):  
Miseon Bang ◽  
Cheng-Chung Yong ◽  
Hyeok-Jin Ko ◽  
In-Geol Choi ◽  
Sejong Oh
Keyword(s):  
Lactobacillus Rhamnosus ◽  
Acid Stress ◽  
Transcriptional Response ◽  
Lactobacillus Rhamnosus Gg ◽  
Adhesion Ability ◽  
Intestinal Adhesion

scholarly journals STUDIES ON DEVELOPMENTAL MECHANISM OF POSTOPERATIVE INTESTINAL ADHESION

1976 ◽  
Vol 9 (6) ◽  
pp. 865-873 ◽  
Author(s):  
Hiromichi YANO ◽  
Hiroyoshi MIZOTE ◽  
Norifumi SHINDO ◽  
Motoki YOSHINARI ◽  
Masanori NOHTOMI ◽  
...  
Keyword(s):  
Developmental Mechanism ◽  
Intestinal Adhesion
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